Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 287656..288686 Replicon plasmid pBEN
Accession NZ_CP038196
Organism Paracoccus versutus strain DSM 17099

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag E3U25_RS01450 Protein ID WP_116221565.1
Coordinates 287656..288225 (-) Length 190 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID -
Locus tag E3U25_RS01455 Protein ID WP_116221566.1
Coordinates 288222..288686 (-) Length 155 a.a.

Genomic Context

E3U25_RS01430E3U25_RS01435E3U25_RS01465E3U25_RS01440E3U25_RS01445E3U25_RS01450E3U25_RS01455E3U25_RS01460
Location: 282747..284099 (1353 bp)
Type: Others
Protein ID: WP_166435464.1
Location: 284092..284958 (867 bp)
Type: Others
Protein ID: WP_116221564.1
Location: 291244..291543 (300 bp)
Type: Others
Protein ID: WP_116221568.1
Location: 285038..285793 (756 bp)
Type: Others
Protein ID: WP_116220987.1
Location: 285790..287244 (1455 bp)
Type: Others
Protein ID: WP_244295116.1
Location: 287656..288225 (570 bp)
Type: Toxin
Protein ID: WP_116221565.1
Location: 288222..288686 (465 bp)
Type: Antitoxin
Protein ID: WP_116221566.1
Location: 288946..290700 (1755 bp)
Type: Others
Protein ID: WP_116221567.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
E3U25_RS01430 (E3U25_01415)282747..284099+1353WP_166435464.1ATP-binding protein-
E3U25_RS01435 (E3U25_01420)284092..284958+867WP_116221564.1hypothetical protein-
E3U25_RS01440 (E3U25_01425)285038..285793-756WP_116220987.1IS21-like element ISPve1 family helper ATPase IstB-
E3U25_RS01445 (E3U25_01430)285790..287244-1455WP_244295116.1IS21-like element ISPve1 family transposase-
E3U25_RS01450 (E3U25_01435)287656..288225-570WP_116221565.1PIN domain-containing proteinToxin
E3U25_RS01455 (E3U25_01440)288222..288686-465WP_116221566.1excisionase family DNA-binding proteinAntitoxin
E3U25_RS01460 (E3U25_01445)288946..290700-1755WP_116221567.1recombinase family protein-
E3U25_RS01465 (E3U25_01450)291244..291543+300WP_116221568.1hypothetical protein-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideNon-Mobilizable plasmid-gmd1..22384392238439


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(7-113)

Antitoxin

Helix-turn-helix domain, group 17

(81-127)


Sequences

Toxin        


Download         Length: 190 a.a.        Molecular weight: 21031.10 Da        Isoelectric Point: 5.0484

>T120796 WP_116221565.1 NZ_CP038196:c288225-287656 [Paracoccus versutus]
MSRYTALLDANVLYPAPLRDLLLQLAVTDLFRARWTADIHREWIEALLRNEPGRDRAALERTRDLMDRATRDSLVEGYHA
LIPALELPDADDRHVLAAAIIGRCDVIVTQNLADFPAEALASFGIDVQHPDEFLVNHLHLAPGLFCASIRKVRARLRNPP
YSVEDYLGTLTQIGLVATAAELGGFAELL

Download         Length: 570 bp

>T120796 NZ_CP038196:c288225-287656 [Paracoccus versutus]
ATGAGCCGTTACACCGCTCTGCTGGATGCGAATGTCCTCTATCCCGCGCCGCTGCGGGATCTGTTGTTGCAACTGGCCGT
CACCGATCTGTTCAGGGCGCGCTGGACGGCCGACATCCATCGCGAATGGATCGAGGCGCTGCTGCGCAACGAACCGGGGC
GGGACCGCGCCGCGCTGGAACGCACCCGCGACCTGATGGACCGGGCTACGCGCGACAGCCTGGTCGAGGGCTACCACGCA
CTGATCCCGGCGCTGGAACTACCGGATGCCGATGACCGGCATGTGCTGGCTGCCGCCATCATCGGGCGTTGCGACGTGAT
CGTGACCCAGAATCTGGCCGACTTCCCGGCCGAGGCGCTGGCGTCGTTTGGCATCGACGTGCAGCACCCGGACGAATTCC
TGGTCAACCACCTGCACCTCGCGCCCGGCCTGTTCTGTGCTTCCATCCGCAAGGTGCGCGCCCGGCTGAGGAACCCGCCT
TATAGCGTCGAGGATTATCTCGGCACCCTGACGCAGATCGGGCTAGTCGCCACAGCGGCCGAGCTCGGCGGGTTTGCCGA
GCTACTTTGA

Antitoxin


Download         Length: 155 a.a.        Molecular weight: 17121.84 Da        Isoelectric Point: 7.3206

>AT120796 WP_116221566.1 NZ_CP038196:c288686-288222 [Paracoccus versutus]
MTMLAHRQLPPSAQDAAIARVSGQLLSRYARQKRPLTLRVTDAEQERPLELPAGAVALLMDILEAMAAGRGVTLMPENAE
LTTVQAAEVLNVSRPFLIKLLDESAIPHRKVGKHRRIRMEDVMAYKAAIDREREAVLDQLVSEAQEQDMGYGRP

Download         Length: 465 bp

>AT120796 NZ_CP038196:c288686-288222 [Paracoccus versutus]
ATGACCATGCTAGCCCATCGACAGCTTCCGCCCTCGGCGCAGGATGCCGCGATTGCGCGCGTGTCCGGCCAGCTTCTGTC
CCGCTATGCCCGTCAGAAGCGGCCACTGACCCTGCGCGTCACCGATGCCGAACAGGAACGCCCGCTGGAACTCCCTGCCG
GGGCGGTCGCCCTGCTGATGGACATCCTGGAGGCAATGGCCGCCGGGCGCGGCGTCACCCTCATGCCCGAGAACGCGGAA
CTGACCACAGTGCAGGCCGCCGAGGTGCTGAACGTCTCGCGCCCATTCCTCATCAAGCTGCTGGACGAAAGCGCGATCCC
GCACCGCAAGGTCGGCAAGCATCGCCGCATCCGCATGGAAGACGTGATGGCCTACAAGGCCGCCATCGACCGCGAACGCG
AGGCCGTGCTCGACCAGCTTGTCAGCGAGGCGCAGGAACAGGATATGGGCTACGGCCGCCCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
No matching records found

Antitoxin

Loading, please wait
Source
ID
Structure
No matching records found

References