Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 1949776..1950416 Replicon chromosome
Accession NZ_CP038101
Organism Saccharomonospora xinjiangensis strain 31sw

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag EYD13_RS09215 Protein ID WP_134714309.1
Coordinates 1949776..1950192 (-) Length 139 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag EYD13_RS09220 Protein ID WP_134714311.1
Coordinates 1950189..1950416 (-) Length 76 a.a.

Genomic Context

EYD13_RS09200EYD13_RS09205EYD13_RS09210EYD13_RS09225EYD13_RS09230EYD13_RS09235EYD13_RS09215EYD13_RS09220EYD13_RS09240
Location: 1946233..1947480 (1248 bp)
Type: Others
Protein ID: WP_134714303.1
Location: 1947477..1948136 (660 bp)
Type: Others
Protein ID: WP_134714305.1
Location: 1948177..1949751 (1575 bp)
Type: Others
Protein ID: WP_134714307.1
Location: 1950467..1951135 (669 bp)
Type: Others
Protein ID: WP_134714313.1
Location: 1951273..1952901 (1629 bp)
Type: Others
Protein ID: WP_134714315.1
Location: 1953272..1953481 (210 bp)
Type: Others
Protein ID: WP_005437638.1
Location: 1949776..1950192 (417 bp)
Type: Toxin
Protein ID: WP_134714309.1
Location: 1950189..1950416 (228 bp)
Type: Antitoxin
Protein ID: WP_134714311.1
Location: 1953468..1954823 (1356 bp)
Type: Others
Protein ID: WP_134714317.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
EYD13_RS092001946233..1947480+1248WP_134714303.1sensor histidine kinase-
EYD13_RS092051947477..1948136+660WP_134714305.1response regulator transcription factor-
EYD13_RS092101948177..1949751+1575WP_134714307.1dNTP triphosphohydrolase-
EYD13_RS092151949776..1950192-417WP_134714309.1PIN domain-containing proteinToxin
EYD13_RS092201950189..1950416-228WP_134714311.1antitoxinAntitoxin
EYD13_RS092251950467..1951135+669WP_134714313.1hypothetical protein-
EYD13_RS092301951273..1952901+1629WP_134714315.1ATP-binding cassette domain-containing protein-
EYD13_RS092351953272..1953481+210WP_005437638.1hypothetical protein-
EYD13_RS092401953468..1954823-1356WP_134714317.1DUF2029 domain-containing protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-121)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 15115.97 Da        Isoelectric Point: 4.6219

>T120692 WP_134714309.1 NZ_CP038101:c1950192-1949776 [Saccharomonospora xinjiangensis]
VTTLLDANVLIALVVADHVHHDVAEEWFARADGGFATCPVTEGSLLRLLIREGQTAENARCVLDSVKEDDRHEFWPDTVS
YSDVPLNGVLGHRQVTDAYLAQLARSRGCRIATFDQGFAELHADVAELVPVVPAQPTR

Download         Length: 417 bp

>T120692 NZ_CP038101:c1950192-1949776 [Saccharomonospora xinjiangensis]
GTGACAACGCTGCTCGACGCCAACGTATTGATCGCCCTCGTGGTCGCCGATCACGTCCACCACGACGTTGCCGAAGAGTG
GTTTGCCCGTGCCGACGGTGGATTCGCCACGTGCCCCGTCACCGAGGGGAGTCTCCTGCGGCTGTTGATCCGCGAAGGGC
AGACGGCGGAGAACGCGCGATGCGTTCTCGACTCGGTCAAAGAGGACGACCGACACGAATTCTGGCCGGACACGGTCAGC
TATAGCGACGTGCCGCTGAACGGAGTGCTCGGGCACCGGCAGGTGACCGACGCCTACCTCGCGCAACTCGCACGGTCGCG
GGGCTGCCGGATCGCCACCTTCGACCAAGGGTTCGCCGAGCTGCACGCGGACGTCGCCGAACTCGTCCCTGTCGTCCCAG
CGCAGCCCACCCGCTGA

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8402.47 Da        Isoelectric Point: 9.1238

>AT120692 WP_134714311.1 NZ_CP038101:c1950416-1950189 [Saccharomonospora xinjiangensis]
MRTTIDLPDDLHRQAQSIARDSSRTLSEIVAELMRRGLGQGKPAETTRSSRTGLPVVRLGRVITTEDVRSLEDER

Download         Length: 228 bp

>AT120692 NZ_CP038101:c1950416-1950189 [Saccharomonospora xinjiangensis]
ATGCGTACGACGATCGATCTGCCCGACGACCTTCATCGGCAGGCTCAGTCCATCGCACGTGACTCTTCCCGCACCTTGAG
CGAGATCGTCGCGGAGCTGATGCGGCGGGGACTGGGGCAGGGCAAACCAGCCGAAACGACACGCAGCTCCCGCACTGGGC
TCCCGGTGGTCAGGCTCGGACGGGTCATCACGACGGAGGACGTCCGTTCACTGGAGGACGAGCGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References