Detailed information of TA system TA120674

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): ParST/RES-Xre
• Location: 2094438..2095207
• Replicon: chromosome
• Accession: NZ_CP038026
• Organism: Massilia plicata strain DSM 17505

Toxin (Protein)

• Gene name: ParT
• Uniprot ID: -
• Locus tag: E1742_RS09235
• Protein ID: WP_134384606.1
• Coordinates: 2094438..2094908 (-)
• Length: 157 a.a.

Antitoxin (Protein)

• Gene name: ParS
• Uniprot ID: -
• Locus tag: E1742_RS09240
• Protein ID: WP_134388101.1
• Coordinates: 2094905..2095207 (-)
• Length: 101 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
E1742_RS09220	2089761..2092154	+	2394	WP_134384603.1	TonB-dependent receptor plug domain-containing protein	-
E1742_RS09225	2092154..2093269	+	1116	WP_134384604.1	glycerophosphodiester phosphodiesterase	-
E1742_RS09230	2093343..2094410	+	1068	WP_134384605.1	SDR family oxidoreductase	-
E1742_RS09235	2094438..2094908	-	471	WP_134384606.1	RES family NAD+ phosphorylase	Toxin
E1742_RS09240	2094905..2095207	-	303	WP_134388101.1	DUF2384 domain-containing protein	Antitoxin
E1742_RS09245	2095477..2096640	-	1164	WP_134384607.1	hemin-degrading factor	-
E1742_RS09250	2096648..2098909	-	2262	WP_134384608.1	TonB-dependent receptor	-
E1742_RS09255	2099084..2099431	-	348	WP_134384609.1	cell division protein FtsB	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (5-144)

Antitoxin

• Antitoxin Xre/MbcA/ParS-like, toxin-binding domain (53-97)

Sequences

Toxin

Protein

• Length: 157 a.a.
• Molecular weight: 17087.52 Da
• Isoelectric Point: 6.4633

>T120674 WP_134384606.1 NZ_CP038026:c2094908-2094438 [Massilia plicata]
MTCALWRIAAVTPAYSADDLSGKGAETTGGRWNLRGTPVVYTSANIALASLETLAHLAVERLPWNRYLVRIDVPDDVYAA
RTVLDPVPAGWDADPYGLPSVQAGEAWCREGRTALLDVPSALVPEERNVLINPRHADAARIGAVMQRKWLVDPRMR

Nucleotide

• Length: 471 bp

>T120674 NZ_CP038026:c2094908-2094438 [Massilia plicata]
ATGACCTGCGCGCTGTGGCGCATTGCCGCGGTCACGCCTGCGTATTCGGCCGATGACCTGAGCGGCAAGGGTGCCGAGAC
CACGGGCGGGCGCTGGAACCTGCGCGGCACGCCGGTCGTCTACACATCGGCCAATATCGCGCTGGCTTCACTGGAGACGC
TGGCGCACCTGGCGGTGGAACGGCTTCCGTGGAACCGGTACCTGGTGCGGATCGACGTGCCGGACGACGTGTATGCCGCG
CGCACCGTGCTCGACCCGGTGCCGGCCGGCTGGGATGCCGATCCGTATGGACTGCCCAGCGTACAGGCCGGCGAAGCATG
GTGCAGGGAAGGGCGGACGGCGCTGCTGGACGTGCCATCCGCGCTGGTGCCGGAGGAGCGCAATGTGCTGATCAATCCGC
GCCATGCGGATGCTGCGCGGATCGGCGCGGTCATGCAGCGCAAGTGGCTGGTCGATCCTCGCATGCGCTGA

Antitoxin

Protein

• Length: 101 a.a.
• Molecular weight: 10860.33 Da
• Isoelectric Point: 5.0338

>AT120674 WP_134388101.1 NZ_CP038026:c2095207-2094905 [Massilia plicata]
MDALGIPRATLNRKVRENRPLPPDESERVLGVKALIGQVQTMVEQSGNAEGFDTLAWLSRWLNTSVPALGGKTPASYLDT
VEGQKYIANLLDMTQSGAYA

Nucleotide

• Length: 303 bp

>AT120674 NZ_CP038026:c2095207-2094905 [Massilia plicata]
ATGGACGCGCTGGGTATTCCGCGCGCCACGCTGAACCGCAAGGTACGCGAGAACCGCCCGCTGCCGCCGGACGAATCGGA
GCGTGTGCTGGGCGTGAAAGCACTGATCGGCCAGGTGCAGACGATGGTCGAACAGTCCGGCAACGCGGAAGGCTTCGATA
CGCTCGCCTGGCTGTCGCGCTGGCTCAACACCTCCGTTCCCGCCCTGGGCGGCAAGACGCCCGCCAGCTACCTCGACACC
GTCGAGGGCCAGAAATACATCGCCAACCTGCTCGACATGACGCAGAGCGGAGCCTATGCATGA