Detailed information of TA system TA120669

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 2605261..2605897
• Replicon: chromosome
• Accession: NZ_CP038022
• Organism: Acinetobacter radioresistens strain DD78

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: E3H47_RS12195
• Protein ID: WP_005024450.1
• Coordinates: 2605261..2605647 (-)
• Length: 129 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: A0A062C3S7
• Locus tag: E3H47_RS12200
• Protein ID: WP_005018377.1
• Coordinates: 2605640..2605897 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
E3H47_RS12180	2600559..2602838	-	2280	WP_138000887.1	TRAP transporter large permease subunit	-
E3H47_RS12185	2602997..2603590	-	594	WP_005024454.1	rhombosortase	-
E3H47_RS12190	2603668..2604783	-	1116	WP_005024452.1	hypothetical protein	-
E3H47_RS12195	2605261..2605647	-	387	WP_005024450.1	hypothetical protein	Toxin
E3H47_RS12200	2605640..2605897	-	258	WP_005018377.1	succinate dehydrogenase assembly factor 2	Antitoxin
E3H47_RS12205	2606081..2607253	+	1173	WP_138000888.1	acyl-CoA dehydrogenase family protein	-
E3H47_RS12210	2607307..2608797	-	1491	WP_034682835.1	NAD(P)/FAD-dependent oxidoreductase	-
E3H47_RS12215	2608978..2609355	-	378	WP_005018373.1	50S ribosomal protein L17	-
E3H47_RS12220	2609374..2610381	-	1008	WP_005018365.1	DNA-directed RNA polymerase subunit alpha	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (10-82)

Sequences

Toxin

Protein

• Length: 129 a.a.
• Molecular weight: 15190.64 Da
• Isoelectric Point: 10.2575

>T120669 WP_005024450.1 NZ_CP038022:c2605647-2605261 [Acinetobacter radioresistens]
MVKQCFKLKPSRMAIMVQLSLLLGLLILFYSLLPLGLWLLCSVIGLISYSLFLKAPRPVRFEYLDAEEWTLQFCKAKHLD
RVVIRKIIDHQLYIVIYFQKNQVKPLVIWSDQLSLVYWKKLKMLAKLY

Nucleotide

• Length: 387 bp

>T120669 NZ_CP038022:c2605647-2605261 [Acinetobacter radioresistens]
ATGGTTAAGCAGTGTTTTAAGCTGAAACCTAGCCGCATGGCTATTATGGTTCAGCTTTCTTTACTACTCGGTTTGCTGAT
TTTGTTCTATTCACTACTACCGTTGGGGCTATGGCTACTCTGTTCTGTCATTGGTTTGATAAGTTATAGCTTATTTTTAA
AAGCGCCGCGTCCTGTACGCTTTGAATATCTAGATGCTGAAGAATGGACTCTTCAGTTCTGTAAAGCTAAACACTTAGAT
CGTGTTGTGATTCGAAAGATAATTGATCATCAACTTTATATTGTAATTTATTTTCAGAAAAATCAGGTTAAACCCTTGGT
TATCTGGAGTGATCAATTGTCTCTTGTATACTGGAAAAAATTAAAAATGTTAGCCAAGCTGTATTAG

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 10209.70 Da
• Isoelectric Point: 4.5925

>AT120669 WP_005018377.1 NZ_CP038022:c2605897-2605640 [Acinetobacter radioresistens]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKQYYLQADAEEKATFAELVAQEDPDLLDWFMEVSEPPRPEMKQLIIKLK
HYVHG

Nucleotide

• Length: 258 bp

>AT120669 NZ_CP038022:c2605897-2605640 [Acinetobacter radioresistens]
ATGTCTGAAGAAATGACTTTGGAAGAACGTAAAGTAATTTACCGTGCACGCCGGGGATTAAAAGAAATTGATGTATATTT
TGACCCTTATGTAAAACAATATTATTTACAAGCTGATGCGGAAGAAAAAGCCACCTTCGCCGAGCTCGTCGCACAGGAAG
ATCCTGATCTTCTAGACTGGTTTATGGAGGTTTCTGAACCTCCACGTCCGGAGATGAAACAGCTAATCATTAAACTTAAA
CATTATGTCCATGGTTAA

Structures

Antitoxin

• AlphaFold DB: A0A062C3S7