Detailed information of TA system TA120639

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 454373..455012
• Replicon: chromosome
• Accession: NZ_CP038009
• Organism: Acinetobacter haemolyticus strain TJR01

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: N9FC12
• Locus tag: AHTJR_RS02185
• Protein ID: WP_005086824.1
• Coordinates: 454617..455012 (+)
• Length: 132 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: N9FB90
• Locus tag: AHTJR_RS02180
• Protein ID: WP_004641025.1
• Coordinates: 454373..454630 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AHTJR_RS02155	449447..449812	+	366	WP_004641032.1	50S ribosomal protein L17	-
AHTJR_RS02160	449977..450474	+	498	WP_134251440.1	GNAT family N-acetyltransferase	-
AHTJR_RS02165	450852..452342	+	1491	WP_005086827.1	NAD(P)/FAD-dependent oxidoreductase	-
AHTJR_RS02170	452465..452962	+	498	WP_134251442.1	DUF2059 domain-containing protein	-
AHTJR_RS02175	453014..454186	-	1173	WP_005086825.1	acyl-CoA dehydrogenase family protein	-
AHTJR_RS02180	454373..454630	+	258	WP_004641025.1	succinate dehydrogenase assembly factor 2	Antitoxin
AHTJR_RS02185	454617..455012	+	396	WP_005086824.1	hypothetical protein	Toxin
AHTJR_RS02190	455223..455429	+	207	WP_026056364.1	hypothetical protein	-
AHTJR_RS02195	455789..456832	+	1044	WP_004641019.1	hypothetical protein	-
AHTJR_RS02200	456960..457541	+	582	WP_004641018.1	rhombosortase	-
AHTJR_RS02205	457719..459929	+	2211	WP_004641016.1	TRAP transporter large permease subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (10-82)

Sequences

Toxin

Protein

• Length: 132 a.a.
• Molecular weight: 16125.42 Da
• Isoelectric Point: 9.1887

>T120639 WP_005086824.1 NZ_CP038009:454617-455012 [Acinetobacter haemolyticus]
MSTADRVFVLKRSRFAFAFQLFIFIVLISLLYYLLPWFLWLVSFPLMLIAWVLLLKQPQLKHFEYLDDQLCSLCFSDEMQ
RIEQRKIRKMIDHQCYIVIYFYDSQCRPCVIWWDQLSILQWKKLKTWVKLA

Nucleotide

• Length: 396 bp

>T120639 NZ_CP038009:454617-455012 [Acinetobacter haemolyticus]
ATGTCCACGGCTGATCGTGTTTTTGTGTTGAAACGCAGTCGTTTTGCATTTGCGTTTCAACTTTTTATTTTTATCGTACT
GATCAGTTTATTGTATTACTTACTTCCTTGGTTTTTATGGCTTGTTAGCTTTCCTTTGATGCTAATTGCTTGGGTATTAT
TACTCAAACAACCTCAGCTTAAACACTTTGAATATTTAGATGATCAGCTTTGCTCCTTGTGTTTTAGTGATGAGATGCAG
AGGATCGAGCAAAGGAAAATTCGAAAAATGATCGATCATCAATGTTATATCGTCATCTATTTTTATGACTCTCAATGTCG
ACCTTGTGTGATTTGGTGGGATCAATTGTCGATTTTACAGTGGAAAAAGCTCAAAACATGGGTCAAACTTGCATAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9982.42 Da
• Isoelectric Point: 4.4558

>AT120639 WP_004641025.1 NZ_CP038009:454373-454630 [Acinetobacter haemolyticus]
MSEELTLEERKVIYRARRGLKEIDVYFDPYVKNCYLTADAAEKALFAELVDQEDPDLLDWFMEVGEPPRPELKAFISKLK
QYVHG

Nucleotide

• Length: 258 bp

>AT120639 NZ_CP038009:454373-454630 [Acinetobacter haemolyticus]
ATGTCTGAAGAATTGACACTAGAAGAACGTAAAGTGATTTATCGTGCGCGTCGTGGTTTGAAAGAAATCGATGTGTATTT
TGATCCTTATGTCAAAAATTGTTATCTCACAGCAGATGCGGCTGAGAAAGCATTGTTTGCAGAGTTGGTAGATCAAGAAG
ATCCTGATTTACTGGATTGGTTCATGGAGGTGGGTGAACCTCCTCGTCCAGAGTTAAAAGCGTTTATTTCAAAATTAAAA
CAGTATGTCCACGGCTGA

Structures

Toxin

• AlphaFold DB: N9FC12

Antitoxin

• AlphaFold DB: N9FB90