Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 3262535..3262769 | Replicon | chromosome |
| Accession | NZ_CP037996 | ||
| Organism | Shigella flexneri strain FC906 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 3262536..3262639 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 3262535..3262769 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| CBL25_RS16625 | 3257980..3258447 | - | 468 | Protein_3196 | DNA-binding transcriptional regulator PgrR | - |
| CBL25_RS16630 | 3258511..3258821 | + | 311 | Protein_3197 | transposase | - |
| CBL25_RS16635 | 3258864..3260061 | - | 1198 | Protein_3198 | IS3 family transposase | - |
| CBL25_RS16640 | 3260116..3260964 | + | 849 | Protein_3199 | IS3-like element IS600 family transposase | - |
| CBL25_RS16645 | 3261081..3261362 | + | 282 | WP_005127484.1 | excisionase | - |
| CBL25_RS16650 | 3261328..3262404 | + | 1077 | Protein_3201 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 3262535..3262769 | + | 235 | - | - | Antitoxin |
| - | 3262536..3262639 | - | 104 | - | - | Toxin |
| CBL25_RS16655 | 3262797..3263138 | - | 342 | WP_000976476.1 | YebY family protein | - |
| CBL25_RS16660 | 3263151..3264023 | - | 873 | Protein_3203 | copper homeostasis membrane protein CopD | - |
| CBL25_RS16665 | 3264027..3264401 | - | 375 | WP_000168747.1 | CopC domain-containing protein YobA | - |
| CBL25_RS16670 | 3264540..3264770 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| CBL25_RS16675 | 3264872..3265528 | + | 657 | Protein_3206 | carbon-nitrogen hydrolase family protein | - |
| CBL25_RS16680 | 3265552..3266214 | + | 663 | WP_000944268.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 3257980..3288121 | 30141 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T120616 NZ_CP037996:c3262639-3262536 [Shigella flexneri]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT120616 NZ_CP037996:3262535-3262769 [Shigella flexneri]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
