Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 3090773..3091812 Replicon chromosome
Accession NZ_CP037993
Organism Herbaspirillum huttiense strain NFYY 53159

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag E2K99_RS13935 Protein ID WP_134222601.1
Coordinates 3091237..3091812 (+) Length 192 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID -
Locus tag E2K99_RS13930 Protein ID WP_134222600.1
Coordinates 3090773..3091240 (+) Length 156 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E2K99_RS13905 3085783..3087078 + 1296 WP_134222595.1 extracellular solute-binding protein -
E2K99_RS13910 3087087..3087971 + 885 WP_134222596.1 sugar ABC transporter permease -
E2K99_RS13915 3087965..3088861 + 897 WP_134222597.1 ABC transporter permease subunit -
E2K99_RS13920 3088913..3089611 - 699 WP_134222598.1 type 1 glutamine amidotransferase domain-containing protein -
E2K99_RS13925 3089746..3090657 + 912 WP_205703676.1 LysR family transcriptional regulator -
E2K99_RS13930 3090773..3091240 + 468 WP_134222600.1 helix-turn-helix domain-containing protein Antitoxin
E2K99_RS13935 3091237..3091812 + 576 WP_134222601.1 PIN domain-containing protein Toxin
E2K99_RS13940 3091961..3093286 - 1326 WP_121041495.1 dicarboxylate/amino acid:cation symporter -
E2K99_RS13945 3093597..3095183 + 1587 WP_134222602.1 Tar ligand binding domain-containing protein -
E2K99_RS13950 3095193..3095624 - 432 WP_134222603.1 GNAT family N-acetyltransferase -
E2K99_RS13955 3095662..3096096 - 435 WP_039787905.1 PaaI family thioesterase -
E2K99_RS13960 3096104..3096406 - 303 WP_134222604.1 Dabb family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(9-114)

Antitoxin

Helix-turn-helix domain, group 17

(84-133)


Sequences

Toxin        


Download         Length: 192 a.a.        Molecular weight: 21407.67 Da        Isoelectric Point: 6.3292

>T120601 WP_134222601.1 NZ_CP037993:3091237-3091812 [Herbaspirillum huttiense]
MRHSPFTALYDACVLYPAALRDFLMCLGLSGCFRARWSRAIHDEWKRNLLINRPDLAKAQLDRTSDLMDRAIPDSLVEGY
EDLIPGLSLPDADDRHVLAAAIRCGASVIVTFNARDFPPKALAPYGIEPQHPDEFVHNLMDLDAAAVTTAAQQQRARLKN
PPIEVETYLDILLRQGLVQTVKALWAYRAVL

Download         Length: 576 bp

>T120601 NZ_CP037993:3091237-3091812 [Herbaspirillum huttiense]
ATGAGGCATTCCCCCTTTACAGCCCTCTACGATGCATGCGTTCTCTATCCTGCCGCCTTGCGGGACTTCCTCATGTGCCT
CGGGCTCTCGGGGTGCTTTCGCGCGCGCTGGAGCAGGGCCATTCACGACGAATGGAAACGAAATCTGCTGATCAATCGTC
CCGACCTGGCAAAAGCCCAGTTGGACCGGACGTCCGACCTGATGGACCGCGCTATTCCAGACAGCCTGGTGGAAGGATAT
GAAGACTTGATACCGGGCCTGTCCCTCCCCGATGCCGATGACCGACACGTACTGGCGGCAGCCATCCGATGCGGAGCAAG
CGTGATCGTGACGTTCAACGCGCGCGACTTTCCGCCCAAGGCACTCGCCCCCTACGGCATCGAACCGCAACATCCCGACG
AATTCGTCCATAACCTCATGGACCTGGATGCCGCAGCAGTCACGACAGCCGCGCAACAACAGCGAGCCAGATTGAAAAAT
CCACCGATCGAAGTGGAGACCTATCTCGATATCCTGTTGCGCCAAGGGCTGGTGCAGACCGTCAAGGCGCTCTGGGCCTA
TCGCGCCGTCCTCTGA

Antitoxin


Download         Length: 156 a.a.        Molecular weight: 17379.98 Da        Isoelectric Point: 7.0759

>AT120601 WP_134222600.1 NZ_CP037993:3090773-3091240 [Herbaspirillum huttiense]
MTMSATSNMSLPAAKEVEIAVKGQRALAAYLSTKLDTQRIQIFDEHNRPHAIELPTSALRLLVQILAELADGNAVNVVPV
HAELTTQEAADLLNVSRPHFVKLLEEGLIPFHRAGKHRRVKFADLMRYKQERRRISTEALDELAQQAQELGMGYE

Download         Length: 468 bp

>AT120601 NZ_CP037993:3090773-3091240 [Herbaspirillum huttiense]
ATGACCATGTCTGCTACCTCCAACATGTCCCTCCCCGCCGCCAAGGAAGTCGAGATCGCCGTCAAAGGCCAGCGCGCACT
GGCCGCCTATCTGAGCACCAAGCTCGATACCCAGCGCATCCAGATCTTCGATGAACACAACCGCCCGCACGCCATCGAAC
TGCCCACGTCGGCCTTGCGCCTGCTGGTGCAGATCCTTGCCGAGCTGGCTGACGGAAATGCGGTCAACGTGGTCCCGGTA
CACGCCGAGCTGACCACACAAGAAGCGGCGGACCTGCTCAACGTCTCGCGCCCACATTTCGTCAAGCTGCTGGAAGAGGG
CCTGATCCCATTCCATCGCGCAGGCAAGCATCGGCGCGTGAAATTTGCCGACCTGATGCGCTACAAGCAAGAGCGCCGAC
GAATCAGCACAGAAGCCCTGGACGAACTCGCGCAACAGGCCCAGGAATTGGGAATGGGATACGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References