Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1936492..1936637 Replicon chromosome
Accession NZ_CP037963
Organism Klebsiella pneumoniae strain SCKP020135

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1936528..1936630 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1936492..1936637 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CLQ43_RS09690 1931622..1933682 + 2061 WP_004151449.1 oligopeptidase B -
CLQ43_RS09695 1933686..1934345 - 660 WP_021440386.1 exodeoxyribonuclease X -
CLQ43_RS09700 1934424..1934654 - 231 WP_002911406.1 DNA polymerase III subunit theta -
CLQ43_RS09705 1934767..1935141 + 375 WP_004151448.1 CopC domain-containing protein YobA -
CLQ43_RS09710 1935145..1936014 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
CLQ43_RS09715 1936031..1936369 + 339 WP_002911404.1 YebY family protein -
- 1936492..1936637 - 146 - - Antitoxin
- 1936528..1936630 + 103 - - Toxin
CLQ43_RS28425 1937006..1937149 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
CLQ43_RS09725 1937254..1938222 - 969 WP_004151446.1 VirK/YbjX family protein -
CLQ43_RS09730 1938379..1939032 + 654 WP_009484457.1 protein-serine/threonine phosphatase -
CLQ43_RS09735 1939029..1939220 - 192 WP_002911395.1 YebW family protein -
CLQ43_RS09740 1939318..1939557 - 240 WP_002911393.1 YebV family protein -
CLQ43_RS09745 1939673..1941106 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1871691..1949707 78016


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T120569 NZ_CP037963:1936528-1936630 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT120569 NZ_CP037963:c1936637-1936492 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References