Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 5374055..5374608 Replicon chromosome
Accession NZ_CP037952
Organism Parashewanella spongiae strain HJ039

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag E2I05_RS21405 Protein ID WP_121855205.1
Coordinates 5374055..5374363 (-) Length 103 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag E2I05_RS21410 Protein ID WP_121855204.1
Coordinates 5374351..5374608 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E2I05_RS21385 5370136..5371158 + 1023 WP_121855143.1 hypothetical protein -
E2I05_RS21390 5371508..5371699 + 192 WP_133309841.1 helix-turn-helix domain-containing protein -
E2I05_RS21395 5371936..5373405 + 1470 WP_133309842.1 ISKra4 family transposase -
E2I05_RS21400 5373566..5373874 + 309 WP_133309843.1 transposase -
E2I05_RS21405 5374055..5374363 - 309 WP_121855205.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
E2I05_RS21410 5374351..5374608 - 258 WP_121855204.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
E2I05_RS21415 5374881..5375132 + 252 WP_121855203.1 hypothetical protein -
E2I05_RS21420 5375921..5376979 + 1059 WP_121855201.1 hypothetical protein -
E2I05_RS21425 5377097..5378362 - 1266 Protein_4180 group II intron reverse transcriptase/maturase -
E2I05_RS22200 5378615..5378755 - 141 WP_170179663.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-66)


Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 11887.74 Da        Isoelectric Point: 5.8552

>T120560 WP_121855205.1 NZ_CP037952:c5374363-5374055 [Parashewanella spongiae]
MAKIVWTEPALSDLNDIAEYIALNNITAAKTLVQNVFKSVERLEDFPSSGRIPPELQHLSYREVIVPPCRIFYKQDNSSI
YILFVMREERDLRKFILDRSLS

Download         Length: 309 bp

>T120560 NZ_CP037952:c5374363-5374055 [Parashewanella spongiae]
ATGGCTAAAATAGTTTGGACTGAACCAGCCTTATCAGACTTAAATGATATCGCCGAATATATTGCTTTAAACAATATCAC
AGCAGCCAAAACACTAGTTCAAAACGTTTTTAAAAGTGTCGAACGTTTAGAAGACTTTCCTAGCTCTGGACGAATTCCAC
CTGAGTTACAGCATTTAAGTTACCGAGAAGTAATCGTACCTCCATGTCGCATTTTCTATAAACAAGATAACAGTAGCATC
TACATACTTTTTGTTATGCGTGAAGAGCGTGATTTACGGAAATTTATTTTAGATAGATCGCTTTCTTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9740.31 Da        Isoelectric Point: 6.4730

>AT120560 WP_121855204.1 NZ_CP037952:c5374608-5374351 [Parashewanella spongiae]
MKVELVTALKRQATKILADLHLTKEPVLITEHGKPSAYLVDVEDYEFMQNRLTILEGIARGERAIIENRTSTLEEAKESM
SKWLK

Download         Length: 258 bp

>AT120560 NZ_CP037952:c5374608-5374351 [Parashewanella spongiae]
ATGAAAGTAGAACTTGTGACAGCACTTAAGCGCCAAGCTACAAAAATACTGGCAGATCTTCACTTGACCAAAGAGCCTGT
ACTTATCACCGAACATGGTAAGCCCTCTGCCTACTTAGTAGATGTGGAAGATTATGAATTCATGCAGAATCGACTTACGA
TTCTAGAAGGTATAGCTCGTGGTGAACGAGCAATTATTGAGAATAGAACTTCAACTCTTGAAGAAGCTAAGGAATCGATG
TCTAAATGGCTAAAATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References