Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 3820989..3821545 Replicon chromosome
Accession NZ_CP037952
Organism Parashewanella spongiae strain HJ039

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag E2I05_RS15200 Protein ID WP_121854768.1
Coordinates 3821264..3821545 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag E2I05_RS15195 Protein ID WP_121854767.1
Coordinates 3820989..3821267 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E2I05_RS15165 3817103..3817381 - 279 WP_121855061.1 GNAT family N-acetyltransferase -
E2I05_RS15170 3817523..3817717 - 195 Protein_2964 GNAT family N-acetyltransferase -
E2I05_RS15175 3817920..3819527 - 1608 WP_133309504.1 transposase -
E2I05_RS15180 3819618..3819950 - 333 WP_133309503.1 IS66 family insertion sequence element accessory protein TnpB -
E2I05_RS15185 3819947..3820318 - 372 WP_133309722.1 hypothetical protein -
E2I05_RS15190 3820714..3820920 + 207 WP_121854766.1 helix-turn-helix domain-containing protein -
E2I05_RS15195 3820989..3821267 + 279 WP_121854767.1 damage-inducible protein J Antitoxin
E2I05_RS15200 3821264..3821545 + 282 WP_121854768.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
E2I05_RS15205 3821565..3822881 - 1317 WP_121854769.1 site-specific integrase -
E2I05_RS15210 3823680..3824900 - 1221 WP_121854770.1 J domain-containing protein -
E2I05_RS15215 3825188..3825769 - 582 WP_121854771.1 ATP-dependent RecD-like DNA helicase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 3812004..3855315 43311


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-89)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 11109.72 Da        Isoelectric Point: 4.2900

>T120559 WP_121854768.1 NZ_CP037952:3821264-3821545 [Parashewanella spongiae]
MIYWEEESLNDREAIFEFLYEVNPFAAEKTDEIIEKKVENLIEQPLMGVQRDSIQGRLLIIPEVSMIVSYDIQNDDIRIL
RVLHQKQKFPRTE

Download         Length: 282 bp

>T120559 NZ_CP037952:3821264-3821545 [Parashewanella spongiae]
ATGATTTATTGGGAAGAAGAGTCGCTCAATGATCGTGAAGCTATTTTTGAGTTTCTGTATGAAGTAAACCCGTTTGCCGC
AGAGAAGACCGATGAGATCATCGAGAAGAAAGTTGAGAACCTTATAGAGCAACCACTTATGGGCGTTCAACGTGACAGTA
TACAAGGTCGATTACTTATTATTCCTGAAGTGTCGATGATTGTCTCTTATGATATTCAAAATGATGATATTCGGATTCTG
AGGGTATTGCACCAAAAGCAAAAGTTTCCTAGAACTGAATAA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10620.96 Da        Isoelectric Point: 7.1687

>AT120559 WP_121854767.1 NZ_CP037952:3820989-3821267 [Parashewanella spongiae]
MDTRIQFRVDEETKRLAQLMAESQGRTLSDACRELTEQLAEQQRKAMSHDDWLTEQVNEAFDKMDSGQAVFVSHDKAKSS
MAMRKAKIRNKS

Download         Length: 279 bp

>AT120559 NZ_CP037952:3820989-3821267 [Parashewanella spongiae]
ATGGATACAAGAATTCAATTTCGTGTTGATGAAGAAACAAAACGCTTAGCTCAGTTGATGGCTGAAAGCCAGGGTCGTAC
TTTAAGTGACGCTTGCCGTGAGCTTACTGAACAACTCGCTGAACAACAAAGAAAAGCGATGTCTCATGATGACTGGCTAA
CTGAGCAGGTAAATGAAGCCTTTGATAAAATGGATTCAGGCCAAGCTGTATTTGTTTCTCATGATAAAGCGAAGAGTAGT
ATGGCTATGCGTAAAGCCAAGATACGGAATAAATCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References