Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 2510921..2511464 Replicon chromosome
Accession NZ_CP037952
Organism Parashewanella spongiae strain HJ039

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag E2I05_RS09690 Protein ID WP_121855187.1
Coordinates 2511192..2511464 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag E2I05_RS09685 Protein ID WP_121855189.1
Coordinates 2510921..2511190 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E2I05_RS09670 2506647..2507552 - 906 WP_133309604.1 ISAs1 family transposase -
E2I05_RS09675 2507613..2507855 - 243 Protein_1885 group II intron reverse transcriptase/maturase -
E2I05_RS09680 2508397..2510460 + 2064 WP_121855188.1 hypothetical protein -
E2I05_RS09685 2510921..2511190 + 270 WP_121855189.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
E2I05_RS09690 2511192..2511464 + 273 WP_121855187.1 type II toxin-antitoxin system YafQ family toxin Toxin
E2I05_RS09695 2511714..2512316 - 603 WP_133309605.1 IS630 family transposase -
E2I05_RS22015 2512198..2512479 - 282 WP_170179598.1 hypothetical protein -
E2I05_RS09700 2513254..2514534 + 1281 WP_133309606.1 group II intron reverse transcriptase/maturase -
E2I05_RS09705 2514651..2515103 - 453 WP_133309607.1 helix-turn-helix domain-containing protein -
E2I05_RS09710 2515126..2515383 + 258 WP_179952741.1 MarR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(1-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-85)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10320.89 Da        Isoelectric Point: 9.3288

>T120554 WP_121855187.1 NZ_CP037952:2511192-2511464 [Parashewanella spongiae]
MYQLEYSSQFKKDFKKVAKLAIPDVIEVGHVITALQQGQTLAAKYVDHALSGNWANYRDYHVKPDLVLIFKVEDNTLKLA
RIGSHSELFR

Download         Length: 273 bp

>T120554 NZ_CP037952:2511192-2511464 [Parashewanella spongiae]
ATGTATCAACTCGAATACTCGAGCCAATTTAAGAAAGATTTTAAAAAGGTCGCTAAACTTGCAATTCCAGATGTGATTGA
AGTCGGTCATGTCATAACCGCATTGCAGCAAGGGCAAACGCTAGCGGCGAAATATGTAGATCATGCTTTATCAGGTAATT
GGGCTAATTATCGAGACTACCATGTTAAGCCTGATTTAGTTTTGATATTTAAAGTAGAAGATAATACCCTGAAGCTCGCA
AGAATTGGCTCACACAGTGAATTGTTTCGTTAA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9823.31 Da        Isoelectric Point: 5.8554

>AT120554 WP_121855189.1 NZ_CP037952:2510921-2511190 [Parashewanella spongiae]
MKTEMLSTRIDQDTKLAFIHICDEVGLSPSQALKLFAKAVINYGGIPFELRSRTPNAKTLEAIKELEDSKGNKADDVKAL
FKELGVNEA

Download         Length: 270 bp

>AT120554 NZ_CP037952:2510921-2511190 [Parashewanella spongiae]
ATGAAGACAGAAATGCTCAGCACTCGTATCGATCAAGATACCAAATTGGCCTTCATTCACATCTGTGATGAGGTAGGGTT
AAGCCCATCACAAGCGCTCAAATTGTTTGCTAAAGCGGTGATCAATTATGGCGGTATCCCGTTTGAACTGCGCTCAAGAA
CACCTAATGCAAAGACACTGGAAGCTATTAAAGAACTTGAAGATAGTAAAGGCAACAAAGCTGATGATGTCAAAGCGTTA
TTTAAAGAGCTCGGAGTGAATGAGGCATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References