Detailed information of TA system TA120553

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 2285588..2286113
• Replicon: chromosome
• Accession: NZ_CP037952
• Organism: Parashewanella spongiae strain HJ039

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: E2I05_RS08770
• Protein ID: WP_121854454.1
• Coordinates: 2285829..2286113 (+)
• Length: 95 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: E2I05_RS08765
• Protein ID: WP_121854455.1
• Coordinates: 2285588..2285839 (+)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
E2I05_RS08735	2282336..2282668	-	333	WP_121854460.1	VirB3 family type IV secretion system protein	-
E2I05_RS08740	2282680..2282949	-	270	WP_121854469.1	TrbC/VirB2 family protein	-
E2I05_RS21995	2283303..2283464	+	162	WP_165905539.1	hypothetical protein	-
E2I05_RS08745	2283507..2283881	+	375	WP_121854459.1	DUF2750 domain-containing protein	-
E2I05_RS08750	2283955..2284164	+	210	WP_121854458.1	hypothetical protein	-
E2I05_RS08755	2284175..2284585	+	411	WP_121854457.1	GFA family protein	-
E2I05_RS08760	2284647..2285438	+	792	WP_121854456.1	crotonase/enoyl-CoA hydratase family protein	-
E2I05_RS08765	2285588..2285839	+	252	WP_121854455.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
E2I05_RS08770	2285829..2286113	+	285	WP_121854454.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
E2I05_RS08775	2286425..2289961	+	3537	WP_133309573.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-85)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (11-71)

Sequences

Toxin

Protein

• Length: 95 a.a.
• Molecular weight: 10884.95 Da
• Isoelectric Point: 10.4664

>T120553 WP_121854454.1 NZ_CP037952:2285829-2286113 [Parashewanella spongiae]
MTYKLKFLPAAQKEWGKLGAPIQKQFKKKLIERLENPHVPAAKLKGYESVYKIKLRTAGYRLAYEVIDDEIVVYVLAVGK
RDKNQVYKKLASRC

Nucleotide

• Length: 285 bp

>T120553 NZ_CP037952:2285829-2286113 [Parashewanella spongiae]
ATGACTTATAAGTTAAAGTTTCTTCCTGCCGCACAAAAAGAGTGGGGTAAGTTGGGCGCTCCAATACAAAAACAGTTTAA
GAAAAAGCTCATAGAGCGATTAGAAAATCCGCATGTACCAGCAGCAAAACTCAAAGGCTATGAATCAGTTTATAAAATTA
AACTCAGAACCGCAGGTTATCGACTGGCGTATGAAGTCATTGATGACGAAATTGTGGTCTATGTTCTGGCCGTTGGCAAG
CGAGATAAGAATCAAGTTTATAAAAAGCTAGCTTCCCGCTGTTAG

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9131.26 Da
• Isoelectric Point: 3.9248

>AT120553 WP_121854455.1 NZ_CP037952:2285588-2285839 [Parashewanella spongiae]
MRQILADCSASISELKQNPTALLNEADGSAIAILNHNKPTAYLVPAETYEYLMDALDDVELGEIVKERRADLTQAVEVDI
NDL

Nucleotide

• Length: 252 bp

>AT120553 NZ_CP037952:2285588-2285839 [Parashewanella spongiae]
ATGAGACAAATTTTAGCTGATTGTTCAGCAAGTATTTCTGAACTTAAACAAAATCCAACAGCATTGCTAAACGAAGCTGA
TGGTTCAGCAATTGCAATTTTAAATCATAACAAACCTACGGCTTACTTAGTACCTGCTGAAACTTACGAGTATCTTATGG
ATGCTTTGGATGACGTTGAACTTGGTGAAATTGTCAAAGAAAGGCGAGCTGATTTAACCCAGGCAGTAGAAGTAGATATT
AATGACTTATAA