Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 2285588..2286113 Replicon chromosome
Accession NZ_CP037952
Organism Parashewanella spongiae strain HJ039

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag E2I05_RS08770 Protein ID WP_121854454.1
Coordinates 2285829..2286113 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag E2I05_RS08765 Protein ID WP_121854455.1
Coordinates 2285588..2285839 (+) Length 84 a.a.

Genomic Context

E2I05_RS21995E2I05_RS08745E2I05_RS08750E2I05_RS08755E2I05_RS08760E2I05_RS08765E2I05_RS08770E2I05_RS08775E2I05_RS08735E2I05_RS08740
Location: 2283303..2283464 (162 bp)
Type: Others
Protein ID: WP_165905539.1
Location: 2283507..2283881 (375 bp)
Type: Others
Protein ID: WP_121854459.1
Location: 2283955..2284164 (210 bp)
Type: Others
Protein ID: WP_121854458.1
Location: 2284175..2284585 (411 bp)
Type: Others
Protein ID: WP_121854457.1
Location: 2284647..2285438 (792 bp)
Type: Others
Protein ID: WP_121854456.1
Location: 2285588..2285839 (252 bp)
Type: Antitoxin
Protein ID: WP_121854455.1
Location: 2285829..2286113 (285 bp)
Type: Toxin
Protein ID: WP_121854454.1
Location: 2286425..2289961 (3537 bp)
Type: Others
Protein ID: WP_133309573.1
Location: 2282336..2282668 (333 bp)
Type: Others
Protein ID: WP_121854460.1
Location: 2282680..2282949 (270 bp)
Type: Others
Protein ID: WP_121854469.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
E2I05_RS087352282336..2282668-333WP_121854460.1VirB3 family type IV secretion system protein-
E2I05_RS087402282680..2282949-270WP_121854469.1TrbC/VirB2 family protein-
E2I05_RS219952283303..2283464+162WP_165905539.1hypothetical protein-
E2I05_RS087452283507..2283881+375WP_121854459.1DUF2750 domain-containing protein-
E2I05_RS087502283955..2284164+210WP_121854458.1hypothetical protein-
E2I05_RS087552284175..2284585+411WP_121854457.1GFA family protein-
E2I05_RS087602284647..2285438+792WP_121854456.1crotonase/enoyl-CoA hydratase family protein-
E2I05_RS087652285588..2285839+252WP_121854455.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
E2I05_RS087702285829..2286113+285WP_121854454.1type II toxin-antitoxin system RelE/ParE family toxinToxin
E2I05_RS087752286425..2289961+3537WP_133309573.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-85)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(11-71)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10884.95 Da        Isoelectric Point: 10.4664

>T120553 WP_121854454.1 NZ_CP037952:2285829-2286113 [Parashewanella spongiae]
MTYKLKFLPAAQKEWGKLGAPIQKQFKKKLIERLENPHVPAAKLKGYESVYKIKLRTAGYRLAYEVIDDEIVVYVLAVGK
RDKNQVYKKLASRC

Download         Length: 285 bp

>T120553 NZ_CP037952:2285829-2286113 [Parashewanella spongiae]
ATGACTTATAAGTTAAAGTTTCTTCCTGCCGCACAAAAAGAGTGGGGTAAGTTGGGCGCTCCAATACAAAAACAGTTTAA
GAAAAAGCTCATAGAGCGATTAGAAAATCCGCATGTACCAGCAGCAAAACTCAAAGGCTATGAATCAGTTTATAAAATTA
AACTCAGAACCGCAGGTTATCGACTGGCGTATGAAGTCATTGATGACGAAATTGTGGTCTATGTTCTGGCCGTTGGCAAG
CGAGATAAGAATCAAGTTTATAAAAAGCTAGCTTCCCGCTGTTAG

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9131.26 Da        Isoelectric Point: 3.9248

>AT120553 WP_121854455.1 NZ_CP037952:2285588-2285839 [Parashewanella spongiae]
MRQILADCSASISELKQNPTALLNEADGSAIAILNHNKPTAYLVPAETYEYLMDALDDVELGEIVKERRADLTQAVEVDI
NDL

Download         Length: 252 bp

>AT120553 NZ_CP037952:2285588-2285839 [Parashewanella spongiae]
ATGAGACAAATTTTAGCTGATTGTTCAGCAAGTATTTCTGAACTTAAACAAAATCCAACAGCATTGCTAAACGAAGCTGA
TGGTTCAGCAATTGCAATTTTAAATCATAACAAACCTACGGCTTACTTAGTACCTGCTGAAACTTACGAGTATCTTATGG
ATGCTTTGGATGACGTTGAACTTGGTGAAATTGTCAAAGAAAGGCGAGCTGATTTAACCCAGGCAGTAGAAGTAGATATT
AATGACTTATAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References