Detailed information of TA system TA120552

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 1891979..1892507
• Replicon: chromosome
• Accession: NZ_CP037952
• Organism: Parashewanella spongiae strain HJ039

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: E2I05_RS07290
• Protein ID: WP_121855082.1
• Coordinates: 1892223..1892507 (+)
• Length: 95 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: E2I05_RS07285
• Protein ID: WP_121855083.1
• Coordinates: 1891979..1892233 (+)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
E2I05_RS07270	1888667..1889035	+	369	WP_121854932.1	hypothetical protein	-
E2I05_RS07275	1889574..1890026	+	453	WP_133309547.1	IS110 family transposase	-
E2I05_RS07280	1890081..1891150	+	1070	Protein_1421	transposase	-
E2I05_RS07285	1891979..1892233	+	255	WP_121855083.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
E2I05_RS07290	1892223..1892507	+	285	WP_121855082.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
E2I05_RS07295	1892814..1893686	-	873	WP_121855081.1	SWIM zinc finger family protein	-
E2I05_RS07300	1893686..1896724	-	3039	WP_121855085.1	DEAD/DEAH box helicase	-
E2I05_RS07305	1896737..1897267	-	531	WP_121855080.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-81)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (11-76)

Sequences

Toxin

Protein

• Length: 95 a.a.
• Molecular weight: 11223.20 Da
• Isoelectric Point: 10.6046

>T120552 WP_121855082.1 NZ_CP037952:1892223-1892507 [Parashewanella spongiae]
MTYKLVFKQDAEKEWRKLDSTIKQQFKKRLIERLENPRVEPARLSGVKDCYKIKLRSAGYRLVYQVRDEEIVVSVVAVGK
RERHEVYKAAIKRI

Nucleotide

• Length: 285 bp

>T120552 NZ_CP037952:1892223-1892507 [Parashewanella spongiae]
ATGACTTATAAACTTGTATTCAAACAAGATGCTGAAAAAGAATGGCGAAAATTGGATTCAACAATCAAGCAACAATTCAA
AAAGCGACTTATTGAACGACTAGAAAATCCAAGAGTAGAACCTGCACGACTTAGTGGTGTGAAGGACTGCTATAAAATTA
AATTAAGAAGTGCTGGTTATCGACTCGTATACCAAGTTAGAGATGAAGAAATCGTTGTTTCTGTTGTCGCAGTTGGTAAA
CGTGAGCGGCATGAAGTTTATAAGGCAGCTATAAAGCGAATATAG

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9459.86 Da
• Isoelectric Point: 4.0183

>AT120552 WP_121855083.1 NZ_CP037952:1891979-1892233 [Parashewanella spongiae]
MLSIRPILAENSTSISELKKNPMAVVEQADGFPVAVLNRNQPAFYCVPAEAYELLMDKLEDVELAKLVEERKEQPEIEIS
IDDL

Nucleotide

• Length: 255 bp

>AT120552 NZ_CP037952:1891979-1892233 [Parashewanella spongiae]
ATGTTATCAATTAGACCCATATTGGCTGAAAATTCAACAAGTATTTCTGAGCTAAAAAAAAATCCGATGGCCGTTGTAGA
GCAGGCCGATGGTTTTCCTGTTGCTGTCCTTAACCGAAATCAACCTGCATTTTACTGTGTACCTGCTGAAGCCTATGAGT
TGCTTATGGACAAGCTTGAGGATGTTGAACTCGCTAAGTTGGTTGAAGAACGAAAAGAGCAACCAGAAATAGAGATTAGC
ATAGATGACTTATAA