Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 1219920..1220935 Replicon chromosome
Accession NZ_CP037952
Organism Parashewanella spongiae strain HJ039

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag E2I05_RS04520 Protein ID WP_121853057.1
Coordinates 1220366..1220935 (+) Length 190 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID -
Locus tag E2I05_RS04515 Protein ID WP_121853056.1
Coordinates 1219920..1220366 (+) Length 149 a.a.

Genomic Context

E2I05_RS04505E2I05_RS04515E2I05_RS04520E2I05_RS04530E2I05_RS04535E2I05_RS04540E2I05_RS04545E2I05_RS04550E2I05_RS04490E2I05_RS04495E2I05_RS04500E2I05_RS04525
Location: 1218210..1219355 (1146 bp)
Type: Others
Protein ID: WP_133309417.1
Location: 1219920..1220366 (447 bp)
Type: Antitoxin
Protein ID: WP_121853056.1
Location: 1220366..1220935 (570 bp)
Type: Toxin
Protein ID: WP_121853057.1
Location: 1221890..1222090 (201 bp)
Type: Others
Protein ID: WP_121853059.1
Location: 1222157..1222675 (519 bp)
Type: Others
Protein ID: WP_165905462.1
Location: 1222690..1223064 (375 bp)
Type: Others
Protein ID: WP_121853061.1
Location: 1223121..1223381 (261 bp)
Type: Others
Protein ID: WP_121853062.1
Location: 1223409..1225406 (1998 bp)
Type: Others
Protein ID: WP_121853063.1
Location: 1215211..1215837 (627 bp)
Type: Others
Protein ID: WP_121854903.1
Location: 1215834..1217000 (1167 bp)
Type: Others
Protein ID: WP_121854904.1
Location: 1217352..1218122 (771 bp)
Type: Others
Protein ID: WP_121854905.1
Location: 1221110..1221832 (723 bp)
Type: Others
Protein ID: WP_121853058.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
E2I05_RS044901215211..1215837-627WP_121854903.1peptide chain release factor H-
E2I05_RS044951215834..1217000-1167WP_121854904.1RNA ligase RtcB family protein-
E2I05_RS045001217352..1218122-771WP_121854905.1tyrosine-type recombinase/integrase-
E2I05_RS045051218210..1219355+1146WP_133309417.1ISAs1 family transposase-
E2I05_RS045151219920..1220366+447WP_121853056.1helix-turn-helix domain-containing proteinAntitoxin
E2I05_RS045201220366..1220935+570WP_121853057.1PIN domain-containing proteinToxin
E2I05_RS045251221110..1221832-723WP_121853058.1helix-turn-helix domain-containing protein-
E2I05_RS045301221890..1222090+201WP_121853059.1DNA-binding protein-
E2I05_RS045351222157..1222675+519WP_165905462.1phage regulatory CII family protein-
E2I05_RS045401222690..1223064+375WP_121853061.1hypothetical protein-
E2I05_RS045451223121..1223381+261WP_121853062.1hypothetical protein-
E2I05_RS045501223409..1225406+1998WP_121853063.1replication endonuclease-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideProphage--1215834..12254069572


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(6-113)

Antitoxin

Helix-turn-helix domain, group 17

(78-125)


Sequences

Toxin        


Download         Length: 190 a.a.        Molecular weight: 21462.64 Da        Isoelectric Point: 5.2635

>T120550 WP_121853057.1 NZ_CP037952:1220366-1220935 [Parashewanella spongiae]
MATYTVIFDACVMYPAPLRSLLMYLANTDLFRARWTDQIHDEWIRNLLNNNPSVTEAGLDKVRKLMNSHIPDCLIEGYET
LIDGITLPDVDDRHVVAAAIKGQAESIITFNLKDFPSSALDVYDIYAVHPDEFLSDMFELDASKVIDAARKHRASLRKPA
LTANEYLDCLQRQKLPNFVSKLRSFAITI

Download         Length: 570 bp

>T120550 NZ_CP037952:1220366-1220935 [Parashewanella spongiae]
ATGGCTACCTACACCGTAATCTTTGATGCATGCGTAATGTACCCAGCACCTTTACGCAGTCTATTGATGTATTTAGCAAA
CACTGACTTATTCAGGGCTCGCTGGACTGATCAAATTCACGATGAATGGATTAGAAATCTTCTAAATAATAACCCCTCAG
TAACTGAAGCTGGATTAGATAAAGTACGGAAGCTAATGAACTCTCATATTCCTGATTGTTTGATTGAAGGCTACGAAACC
CTAATAGACGGGATCACTCTGCCAGATGTAGATGATAGACATGTAGTAGCAGCTGCAATCAAAGGGCAAGCTGAGTCAAT
CATTACATTCAACCTCAAAGACTTTCCTTCTTCAGCACTTGATGTATACGATATTTATGCTGTTCATCCAGATGAATTCT
TAAGTGATATGTTTGAACTTGATGCAAGTAAAGTTATTGACGCAGCTCGAAAGCATAGAGCTAGTCTAAGAAAACCAGCT
TTAACAGCCAATGAATACCTTGATTGTTTGCAACGGCAGAAGCTACCAAACTTTGTTTCGAAGCTGAGAAGCTTTGCTAT
TACGATTTGA

Antitoxin


Download         Length: 149 a.a.        Molecular weight: 16102.55 Da        Isoelectric Point: 5.2305

>AT120550 WP_121853056.1 NZ_CP037952:1219920-1220366 [Parashewanella spongiae]
MAITIPSAEEVALAKLGSQELSAFIDVDGSPQKISVLDKAGQKHEVSLPASALKLMVDILTELGQGNSVNITPIHAELTT
QEGADMLNMSRPTFIKLLDNLAIPFHRKGNRRKVAFSDVLAYKQSLKDKRLEALDELSALDQELGMGY

Download         Length: 447 bp

>AT120550 NZ_CP037952:1219920-1220366 [Parashewanella spongiae]
ATGGCAATTACAATACCGAGTGCGGAAGAAGTTGCTTTAGCAAAACTTGGTAGTCAGGAGCTTTCAGCATTTATTGATGT
TGATGGTAGCCCACAAAAAATTAGTGTTCTTGATAAAGCAGGGCAAAAGCATGAAGTGAGTTTACCAGCGAGTGCATTAA
AACTGATGGTTGATATATTAACTGAACTAGGTCAGGGTAATTCTGTGAATATCACACCAATTCATGCTGAACTTACGACT
CAAGAAGGTGCTGACATGCTCAATATGTCACGTCCTACGTTTATTAAATTATTGGATAACTTGGCAATTCCTTTTCACCG
TAAGGGTAATAGGAGAAAAGTCGCTTTCTCTGATGTGTTAGCTTACAAGCAGTCTCTTAAAGATAAAAGACTTGAAGCTT
TAGACGAACTTTCAGCGCTAGATCAGGAATTAGGTATGGGTTACTAA

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
No matching records found

Antitoxin

Loading, please wait
Source
ID
Structure
No matching records found

References