Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mosAT/AbiEii-AbiEi
Location 3804618..3806316 Replicon chromosome
Accession NZ_CP037951
Organism Parashewanella tropica strain MEBiC05444

Toxin (Protein)


Gene name mosT Uniprot ID -
Locus tag E2H97_RS16790 Protein ID WP_133408201.1
Coordinates 3804618..3805541 (-) Length 308 a.a.

Antitoxin (Protein)


Gene name mosA Uniprot ID -
Locus tag E2H97_RS16795 Protein ID WP_133408202.1
Coordinates 3805534..3806316 (-) Length 261 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E2H97_RS16760 3799646..3800821 - 1176 WP_133408195.1 cysteine desulfurase -
E2H97_RS16765 3800823..3801191 - 369 WP_133408196.1 iron-sulfur cluster assembly scaffold protein -
E2H97_RS16770 3801337..3802512 - 1176 WP_133408197.1 LuxE family acyl-protein synthetase -
E2H97_RS16775 3802589..3803356 - 768 WP_133408198.1 helix-turn-helix domain-containing protein -
E2H97_RS16780 3804088..3804291 + 204 WP_133408199.1 helix-turn-helix domain-containing protein -
E2H97_RS16785 3804353..3804589 + 237 WP_133408200.1 AlpA family phage regulatory protein -
E2H97_RS16790 3804618..3805541 - 924 WP_133408201.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
E2H97_RS16795 3805534..3806316 - 783 WP_133408202.1 type IV toxin-antitoxin system AbiEi family antitoxin Antitoxin
E2H97_RS16800 3807039..3808520 + 1482 WP_133408203.1 citrate/2-methylcitrate synthase -
E2H97_RS16805 3808534..3810036 + 1503 WP_133408204.1 acyl--CoA ligase -
E2H97_RS16810 3810042..3811238 + 1197 WP_170308343.1 MFS transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(13-259)

Antitoxin

Transcriptional regulator AbiEi antitoxin, N-terminal domain

(1-97)


Sequences

Toxin        


Download         Length: 308 a.a.        Molecular weight: 34776.24 Da        Isoelectric Point: 6.6577

>T120546 WP_133408201.1 NZ_CP037951:c3805541-3804618 [Parashewanella tropica]
MDKQSVYYRQVTLLMRVLPVVAKESIFALKGGTAINLFVRDFPRLSVDIDLSYLPLEPRDVALSNAKNALSRITTTINEV
RDLTATLQDNRADELRIIVNGNQAQIKIEVSPVARGTLHQPKVMPVSELVEDEFGYAEIAVVSLADLYGGKLCAAMDRQH
PRDLYDVNLLLKNEGISRGTFVGFLTYVLGHPRPINEVMAPNWKDIKDVYDKEFSGMTVDAITIEELKVTRTKMLAALKV
NFTETDRDFLLSFKLGEPKWELFDEPEIQHLPAVKWKLLNLIGLKKRNSEKHQEQLNKLNTALGSWL

Download         Length: 924 bp

>T120546 NZ_CP037951:c3805541-3804618 [Parashewanella tropica]
ATGGATAAGCAATCTGTTTATTATCGACAAGTTACACTGCTCATGAGAGTTCTACCTGTTGTTGCAAAAGAATCTATTTT
TGCGCTCAAGGGAGGAACTGCGATAAATCTCTTTGTTAGAGATTTCCCTCGATTATCTGTAGATATCGATTTGTCCTACT
TACCGCTTGAACCAAGAGATGTGGCATTATCGAACGCTAAAAATGCTCTTTCTAGGATCACAACAACCATTAATGAAGTA
CGAGATTTAACAGCAACTTTGCAAGATAACCGTGCTGATGAATTAAGGATTATTGTGAATGGTAATCAAGCACAGATCAA
AATTGAGGTGTCACCCGTTGCAAGAGGGACATTACATCAACCAAAAGTAATGCCTGTTTCAGAGTTAGTTGAAGATGAAT
TTGGTTATGCTGAAATTGCAGTCGTTAGCCTTGCTGATTTATACGGTGGTAAACTTTGCGCTGCTATGGACAGGCAACAC
CCAAGGGATCTTTATGATGTGAATTTGCTGCTAAAAAATGAAGGTATATCAAGAGGTACTTTTGTTGGCTTTTTAACTTA
TGTGCTTGGACATCCAAGACCTATCAATGAAGTCATGGCACCGAACTGGAAAGACATCAAAGACGTTTATGATAAAGAAT
TCTCAGGTATGACGGTTGATGCAATAACCATCGAAGAGTTAAAAGTAACCAGAACTAAAATGCTTGCAGCGTTGAAAGTC
AACTTCACAGAGACAGATCGAGATTTCTTGCTCTCATTCAAGCTGGGTGAGCCTAAGTGGGAATTATTTGATGAACCAGA
AATACAACACTTACCTGCAGTTAAGTGGAAACTGCTAAACCTAATTGGACTGAAAAAAAGAAACTCTGAGAAACATCAAG
AGCAATTAAATAAGCTCAATACAGCATTAGGGTCATGGTTATAA

Antitoxin


Download         Length: 261 a.a.        Molecular weight: 29508.56 Da        Isoelectric Point: 9.8004

>AT120546 WP_133408202.1 NZ_CP037951:c3806316-3805534 [Parashewanella tropica]
MSSKINWLIQNTIPGSVVLQMWLTQNGINHSLTQRYVASGWLKKISSGVYFRPLSNPDQLPEWTNALQALQKQTNVHVHL
AGLSSLNYQGLSHYLQLSEQKIWLGGASKSSVPKWLAQYPNQTWLYCTNSKLMELSERDFIKVTVNGVDLNASNTELAAY
EVVEAIGKHITFQHAAELFQGLTNLSPRKVQSLLERSNAVQTNRIFLYLSHYYAHQWAVRLNESKINLGTGKRQVVAKGK
FDEHYQITVPETLFHRGENG

Download         Length: 783 bp

>AT120546 NZ_CP037951:c3806316-3805534 [Parashewanella tropica]
ATGTCATCAAAAATAAACTGGCTAATACAAAATACCATCCCCGGTAGTGTTGTTCTTCAAATGTGGCTCACTCAGAATGG
GATCAATCACTCTCTGACACAACGCTATGTGGCGAGCGGTTGGCTGAAAAAAATCAGTTCAGGGGTGTACTTTAGACCCT
TGAGTAACCCTGATCAGTTACCTGAATGGACTAATGCTTTACAGGCGTTGCAAAAGCAGACAAATGTTCATGTGCATCTT
GCTGGATTATCGAGCTTGAACTATCAGGGGTTGAGTCACTATCTACAACTCAGTGAACAGAAAATATGGTTAGGCGGTGC
TTCTAAAAGTTCAGTACCTAAATGGCTTGCACAATACCCTAATCAAACTTGGCTCTACTGCACTAACAGTAAACTAATGG
AACTCTCAGAGAGAGATTTTATCAAAGTGACAGTTAATGGTGTGGACTTGAATGCCAGCAATACTGAGCTTGCTGCCTAT
GAAGTCGTAGAGGCAATAGGGAAGCATATAACCTTTCAGCATGCCGCAGAATTATTTCAAGGTCTAACCAATCTAAGTCC
ACGGAAAGTTCAATCATTACTAGAGCGAAGCAATGCTGTTCAAACCAATCGAATATTTTTGTATTTGAGCCATTACTACG
CCCATCAGTGGGCTGTTCGGTTAAATGAATCAAAGATCAATTTAGGCACAGGGAAGCGTCAGGTCGTAGCAAAAGGGAAG
TTTGATGAACACTATCAAATAACGGTACCAGAAACATTATTCCATCGAGGTGAGAATGGATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References