Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 4424700..4425445 Replicon chromosome
Accession NZ_CP037950
Organism Erwinia sp. QL-Z3

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag E2F51_RS21270 Protein ID WP_134824490.1
Coordinates 4424700..4425191 (-) Length 164 a.a.

Antitoxin (Protein)


Gene name tacA Uniprot ID -
Locus tag E2F51_RS21275 Protein ID WP_134824491.1
Coordinates 4425179..4425445 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E2F51_RS21245 4419954..4420748 - 795 WP_134824486.1 PhzF family phenazine biosynthesis protein -
E2F51_RS21250 4420991..4421611 - 621 WP_134824487.1 LysE family translocator -
E2F51_RS21255 4421790..4422391 - 602 Protein_3998 tyrosine-type recombinase/integrase -
E2F51_RS21260 4422576..4423013 + 438 WP_134824488.1 VOC family protein -
E2F51_RS21265 4423171..4424292 - 1122 WP_134824489.1 serine hydrolase -
E2F51_RS21270 4424700..4425191 - 492 WP_134824490.1 GNAT family N-acetyltransferase Toxin
E2F51_RS21275 4425179..4425445 - 267 WP_134824491.1 DUF1778 domain-containing protein Antitoxin
E2F51_RS21280 4425650..4426720 - 1071 WP_134824492.1 iron-containing alcohol dehydrogenase family protein -
E2F51_RS21285 4426739..4427407 - 669 WP_053142252.1 ABC transporter permease -
E2F51_RS21290 4427395..4428183 - 789 WP_134824493.1 ATP-binding cassette domain-containing protein -
E2F51_RS21295 4428176..4428979 - 804 WP_105759988.1 MetQ/NlpA family ABC transporter substrate-binding protein -
E2F51_RS21300 4428996..4430018 - 1023 WP_134824494.1 isopenicillin N synthase family oxygenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(45-147)

Antitoxin

Vibrio phage ICP1, Orf50

(2-88)


Sequences

Toxin        


Download         Length: 164 a.a.        Molecular weight: 17565.31 Da        Isoelectric Point: 8.3184

>T120541 WP_134824490.1 NZ_CP037950:c4425191-4424700 [Erwinia sp. QL-Z3]
MGKVTAPAPLNTTHILSEFHSGEVALDEWIRLRGLKNQSTGAARTFVVCREDSSQVVGFYSLATGSVTHAIAPGGLRRNM
PDPLPIIILARLAVDSSCQGQGLGADLLHDAVLRICRVAENIGVRAIMVHALSDAAKQFYLHHGFQPSTTLEKTLFLRLP
TAI

Download         Length: 492 bp

>T120541 NZ_CP037950:c4425191-4424700 [Erwinia sp. QL-Z3]
ATGGGAAAAGTAACCGCTCCAGCACCGCTAAATACGACTCACATTCTTTCAGAGTTTCACTCCGGGGAAGTTGCACTGGA
TGAATGGATCAGGCTCAGGGGGTTAAAAAACCAGTCGACCGGCGCCGCCAGAACGTTTGTGGTGTGCCGGGAAGATTCTT
CACAAGTGGTTGGTTTTTACTCTCTGGCCACCGGCAGTGTCACTCATGCCATTGCACCCGGTGGGCTCAGACGAAACATG
CCTGACCCCCTTCCCATCATAATTTTGGCCCGGCTGGCAGTTGATTCGAGTTGCCAGGGCCAGGGTCTTGGTGCGGATTT
ACTGCACGATGCGGTACTCCGTATTTGTCGGGTTGCGGAGAATATTGGCGTCCGGGCCATTATGGTGCATGCCTTATCTG
ATGCGGCAAAACAGTTTTACCTGCATCATGGATTCCAGCCCTCAACGACACTGGAAAAAACACTTTTTCTCCGGTTACCT
ACTGCCATTTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10027.53 Da        Isoelectric Point: 4.7683

>AT120541 WP_134824491.1 NZ_CP037950:c4425445-4425179 [Erwinia sp. QL-Z3]
MKSDVQLNIRAKEAQRVLIDTAAAILHKSRTDFILDIACQAAENVILDRRMFNLDDEQYAEFINMLDAPVTANPALDTLL
ARKPQWEK

Download         Length: 267 bp

>AT120541 NZ_CP037950:c4425445-4425179 [Erwinia sp. QL-Z3]
ATGAAATCTGATGTTCAGCTTAACATTCGGGCTAAAGAAGCCCAGCGCGTGTTGATCGATACCGCTGCCGCTATTCTTCA
TAAATCACGCACCGACTTTATACTAGACATCGCTTGCCAGGCTGCTGAAAACGTTATCCTTGATCGCCGGATGTTTAATC
TTGATGATGAACAGTACGCCGAGTTTATCAATATGCTGGATGCACCCGTTACAGCGAATCCGGCACTGGATACGCTGCTG
GCGAGAAAACCTCAATGGGAAAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References