Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PRK09907-MazE
Location 1137596..1138170 Replicon chromosome
Accession NZ_CP037948
Organism Qipengyuania sediminis strain CGMCC 1.12928

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag E2O00_RS05545 Protein ID WP_133365570.1
Coordinates 1137835..1138170 (+) Length 112 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag E2O00_RS05540 Protein ID WP_133365569.1
Coordinates 1137596..1137835 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E2O00_RS05515 1132869..1133255 - 387 WP_133365566.1 hypothetical protein -
E2O00_RS05520 1133267..1134706 - 1440 WP_133366773.1 DUF2779 domain-containing protein -
E2O00_RS05525 1134766..1135515 - 750 WP_133365567.1 hypothetical protein -
E2O00_RS05530 1135512..1136546 - 1035 WP_133365568.1 WYL domain-containing protein -
E2O00_RS05535 1136631..1137422 - 792 WP_205958416.1 DUF3883 domain-containing protein -
E2O00_RS05540 1137596..1137835 + 240 WP_133365569.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
E2O00_RS05545 1137835..1138170 + 336 WP_133365570.1 endoribonuclease MazF Toxin
E2O00_RS05550 1138211..1139092 - 882 WP_133365571.1 hypothetical protein -
E2O00_RS05555 1139178..1139723 - 546 WP_133365572.1 hypothetical protein -
E2O00_RS05560 1139836..1140720 - 885 WP_133365573.1 DNA polymerase III subunit epsilon -
E2O00_RS05565 1140800..1142850 - 2051 Protein_1099 integrase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(5-111)

Antitoxin

Antitoxin PemI-like

(1-79)


Sequences

Toxin        


Download         Length: 112 a.a.        Molecular weight: 12180.06 Da        Isoelectric Point: 8.5131

>T120537 WP_133365570.1 NZ_CP037948:1137835-1138170 [Qipengyuania sediminis]
MKPGYVPDTGDVVWLHFDPQAGHEQAGHRPALVLSPARYNGVRGMMLCCPMTSRIKGYPFEVVDGDDPPSVVLADQVKSL
DWRAGRAERKGRVSPATLAEVRAKVRALLEL

Download         Length: 336 bp

>T120537 NZ_CP037948:1137835-1138170 [Qipengyuania sediminis]
ATGAAGCCGGGCTATGTCCCGGATACCGGCGACGTCGTCTGGCTCCACTTCGATCCGCAGGCGGGGCACGAGCAGGCGGG
GCACCGCCCGGCGCTGGTGCTGTCCCCCGCGCGCTACAACGGGGTGCGCGGCATGATGCTCTGTTGCCCGATGACCTCGC
GGATCAAGGGCTACCCGTTCGAGGTGGTCGACGGCGACGATCCGCCGAGCGTGGTGTTGGCCGATCAGGTGAAGAGCCTC
GACTGGCGCGCCGGGCGAGCCGAGAGGAAGGGTCGGGTGTCGCCGGCCACGCTAGCGGAAGTGCGCGCGAAGGTCCGCGC
GCTGCTCGAGCTGTAG

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8608.77 Da        Isoelectric Point: 4.2412

>AT120537 WP_133365569.1 NZ_CP037948:1137596-1137835 [Qipengyuania sediminis]
MRVQVKRWGNSASVRIPASVMAAAALRIDQEVNVREDEGRIVIEPVIAPSYDLDSLLAGMAPETFPDEVDFGRPVGQEA

Download         Length: 240 bp

>AT120537 NZ_CP037948:1137596-1137835 [Qipengyuania sediminis]
ATGCGTGTCCAGGTCAAGCGGTGGGGCAACAGCGCCTCGGTGCGCATTCCCGCATCGGTGATGGCGGCGGCGGCCTTGCG
GATCGATCAGGAGGTCAATGTCCGCGAGGACGAGGGAAGGATCGTGATCGAGCCCGTCATCGCGCCGTCCTATGATCTCG
ACTCGTTGCTCGCCGGGATGGCGCCGGAAACCTTCCCCGACGAGGTCGATTTCGGACGCCCGGTCGGACAGGAGGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References