Detailed information of TA system TA120536

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/YafQ-RelB
• Location: 1107803..1108376
• Replicon: chromosome
• Accession: NZ_CP037948
• Organism: Qipengyuania sediminis strain CGMCC 1.12928

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: E2O00_RS05435
• Protein ID: WP_133365552.1
• Coordinates: 1107803..1108132 (-)
• Length: 110 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: E2O00_RS05440
• Protein ID: WP_133366771.1
• Coordinates: 1108125..1108376 (-)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
E2O00_RS05425	1103515..1107000	+	3486	WP_133365550.1	TonB-dependent receptor	-
E2O00_RS05430	1107096..1107416	-	321	WP_133365551.1	hypothetical protein	-
E2O00_RS05435	1107803..1108132	-	330	WP_133365552.1	type II toxin-antitoxin system YafQ family toxin	Toxin
E2O00_RS05440	1108125..1108376	-	252	WP_133366771.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
E2O00_RS05445	1108582..1110753	-	2172	WP_205958414.1	MobA/MobL family protein	-
E2O00_RS05450	1111164..1112033	-	870	WP_133365554.1	hypothetical protein	-
E2O00_RS05455	1112044..1112472	-	429	WP_133365555.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, YafQ-like toxin (15-108)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (1-81)

Sequences

Toxin

Protein

• Length: 110 a.a.
• Molecular weight: 12191.89 Da
• Isoelectric Point: 9.5814

>T120536 WP_133365552.1 NZ_CP037948:c1108132-1107803 [Qipengyuania sediminis]
MAKGAQGKRAPHPRTCDYAKQFSKDWARLSGSGRFDMNRLKSVMLQLIANDVPLGPEWKDHPLKGEWASYRECHIGGDFL
LIYRVDDAARKGGTIVFARAGTHSDLFGE

Nucleotide

• Length: 330 bp

>T120536 NZ_CP037948:c1108132-1107803 [Qipengyuania sediminis]
ATGGCTAAAGGCGCGCAGGGTAAACGCGCGCCGCACCCGCGCACGTGCGACTACGCCAAGCAATTCAGCAAGGACTGGGC
ACGCCTGTCCGGCTCGGGACGGTTCGATATGAACCGCCTGAAGTCGGTGATGCTTCAGTTGATCGCCAATGACGTGCCGC
TCGGCCCGGAATGGAAGGACCACCCGCTCAAAGGCGAATGGGCCAGTTACCGCGAATGCCACATCGGCGGCGATTTCCTC
CTGATCTACCGCGTCGATGACGCTGCCAGGAAGGGCGGCACGATCGTGTTCGCCCGTGCAGGCACGCACAGCGACCTGTT
CGGTGAGTGA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 8804.14 Da
• Isoelectric Point: 5.0334

>AT120536 WP_133366771.1 NZ_CP037948:c1108376-1108125 [Qipengyuania sediminis]
MLHVRLDDEIKAKGNAALAAMGLSAADAVRLLYHRIVAEQAFPLELKVPNADTRAAMAEADAILADRSARFADGKAMIAD
LDG

Nucleotide

• Length: 252 bp

>AT120536 NZ_CP037948:c1108376-1108125 [Qipengyuania sediminis]
ATGCTTCATGTCCGGCTGGACGACGAGATCAAGGCGAAGGGCAATGCCGCGCTGGCGGCAATGGGGCTGTCGGCCGCGGA
TGCGGTGCGGCTGCTCTATCATCGCATCGTGGCGGAGCAGGCATTCCCGCTCGAGCTCAAGGTGCCCAACGCCGATACCC
GCGCGGCGATGGCCGAGGCCGATGCCATCCTTGCGGATCGTTCCGCGCGGTTCGCCGATGGCAAGGCGATGATCGCCGAC
CTGGATGGCTAA