Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 5223975..5224209 | Replicon | chromosome |
| Accession | NZ_CP037945 | ||
| Organism | Escherichia coli strain CFSAN027346 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 5224105..5224208 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 5223975..5224209 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EKI52_RS26860 | 5220530..5221192 | - | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
| EKI52_RS26865 | 5221216..5221872 | - | 657 | WP_000011658.1 | carbon-nitrogen hydrolase family protein | - |
| EKI52_RS26870 | 5221974..5222204 | - | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| EKI52_RS26875 | 5222343..5222717 | + | 375 | WP_000204699.1 | CopC domain-containing protein YobA | - |
| EKI52_RS26880 | 5222721..5223593 | + | 873 | WP_000879280.1 | copper homeostasis membrane protein CopD | - |
| EKI52_RS26885 | 5223606..5223947 | + | 342 | WP_000976492.1 | YebY family protein | - |
| - | 5223975..5224209 | - | 235 | - | - | Antitoxin |
| - | 5224105..5224208 | + | 104 | - | - | Toxin |
| EKI52_RS26890 | 5224300..5225415 | - | 1116 | WP_001189092.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| EKI52_RS26895 | 5225381..5225662 | - | 282 | WP_001443927.1 | excisionase | - |
| EKI52_RS26900 | 5225769..5225957 | - | 189 | WP_001356607.1 | DUF1187 family protein | - |
| - | 5225773..5225951 | + | 179 | NuclAT_1 | - | - |
| - | 5225773..5225951 | + | 179 | NuclAT_1 | - | - |
| - | 5225773..5225951 | + | 179 | NuclAT_1 | - | - |
| - | 5225773..5225951 | + | 179 | NuclAT_1 | - | - |
| EKI52_RS26905 | 5225950..5226144 | - | 195 | WP_042853000.1 | type I toxin-antitoxin system endodeoxyribonuclease toxin RalR | - |
| EKI52_RS26910 | 5226201..5227010 | - | 810 | WP_000166317.1 | recombination protein RecT | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | nleG7' | 5216565..5289464 | 72899 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T120517 NZ_CP037945:5224105-5224208 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT120517 NZ_CP037945:c5224209-5223975 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
