Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 983974..984208 | Replicon | chromosome |
| Accession | NZ_CP037943 | ||
| Organism | Escherichia coli strain CFSAN027343 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 983975..984078 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 983974..984208 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EKI57_RS05480 | 981172..981981 | + | 810 | WP_000166317.1 | recombination protein RecT | - |
| EKI57_RS05485 | 982038..982232 | + | 195 | WP_042853000.1 | type I toxin-antitoxin system endodeoxyribonuclease toxin RalR | - |
| EKI57_RS05490 | 982225..982413 | + | 189 | WP_001356607.1 | DUF1187 family protein | - |
| - | 982231..982409 | - | 179 | NuclAT_1 | - | - |
| - | 982231..982409 | - | 179 | NuclAT_1 | - | - |
| - | 982231..982409 | - | 179 | NuclAT_1 | - | - |
| - | 982231..982409 | - | 179 | NuclAT_1 | - | - |
| EKI57_RS05495 | 982520..982801 | + | 282 | WP_001443927.1 | excisionase | - |
| EKI57_RS05500 | 982767..983843 | + | 1077 | WP_133394882.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 983974..984208 | + | 235 | - | - | Antitoxin |
| - | 983975..984078 | - | 104 | - | - | Toxin |
| EKI57_RS05505 | 984236..984577 | - | 342 | WP_000976492.1 | YebY family protein | - |
| EKI57_RS05510 | 984590..985462 | - | 873 | WP_000879280.1 | copper homeostasis membrane protein CopD | - |
| EKI57_RS05515 | 985466..985840 | - | 375 | WP_000204699.1 | CopC domain-containing protein YobA | - |
| EKI57_RS05520 | 985979..986209 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| EKI57_RS05525 | 986311..986967 | + | 657 | WP_000011658.1 | carbon-nitrogen hydrolase family protein | - |
| EKI57_RS05530 | 986991..987653 | + | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | nleG7' | 921297..991618 | 70321 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T120472 NZ_CP037943:c984078-983975 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT120472 NZ_CP037943:983974-984208 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
