Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 3706920..3707154 | Replicon | chromosome |
| Accession | NZ_CP037941 | ||
| Organism | Escherichia coli strain CFSAN027350 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 3706921..3707024 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 3706920..3707154 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EKI55_RS18910 | 3704118..3704927 | + | 810 | WP_000166317.1 | recombination protein RecT | - |
| EKI55_RS18915 | 3704984..3705178 | + | 195 | WP_050439817.1 | type I toxin-antitoxin system endodeoxyribonuclease toxin RalR | - |
| EKI55_RS18920 | 3705171..3705359 | + | 189 | WP_001356607.1 | DUF1187 family protein | - |
| - | 3705177..3705355 | - | 179 | NuclAT_1 | - | - |
| - | 3705177..3705355 | - | 179 | NuclAT_1 | - | - |
| - | 3705177..3705355 | - | 179 | NuclAT_1 | - | - |
| - | 3705177..3705355 | - | 179 | NuclAT_1 | - | - |
| EKI55_RS18925 | 3705466..3705747 | + | 282 | WP_001443927.1 | excisionase | - |
| EKI55_RS18930 | 3705713..3706789 | + | 1077 | WP_001189091.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 3706920..3707154 | + | 235 | - | - | Antitoxin |
| - | 3706921..3707024 | - | 104 | - | - | Toxin |
| EKI55_RS18935 | 3707182..3707523 | - | 342 | WP_000976492.1 | YebY family protein | - |
| EKI55_RS18940 | 3707536..3708408 | - | 873 | WP_000879280.1 | copper homeostasis membrane protein CopD | - |
| EKI55_RS18945 | 3708412..3708786 | - | 375 | WP_000204699.1 | CopC domain-containing protein YobA | - |
| EKI55_RS18950 | 3708925..3709155 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| EKI55_RS18955 | 3709257..3709913 | + | 657 | WP_000011658.1 | carbon-nitrogen hydrolase family protein | - |
| EKI55_RS18960 | 3709937..3710599 | + | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | nleG7' / espFu/tccP | 3641187..3748118 | 106931 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T120439 NZ_CP037941:c3707024-3706921 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT120439 NZ_CP037941:3706920-3707154 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
