Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1997788..1997933 Replicon chromosome
Accession NZ_CP037928
Organism Klebsiella pneumoniae subsp. pneumoniae strain KP-8788

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1997824..1997926 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1997788..1997933 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E2E32_RS09790 1992918..1994978 + 2061 WP_004151449.1 oligopeptidase B -
E2E32_RS09795 1994982..1995641 - 660 WP_002911407.1 exodeoxyribonuclease X -
E2E32_RS09800 1995720..1995950 - 231 WP_002911406.1 DNA polymerase III subunit theta -
E2E32_RS09805 1996063..1996437 + 375 WP_004151448.1 CopC domain-containing protein YobA -
E2E32_RS09810 1996441..1997310 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
E2E32_RS09815 1997327..1997665 + 339 WP_002911404.1 YebY family protein -
- 1997788..1997933 - 146 - - Antitoxin
- 1997824..1997926 + 103 - - Toxin
E2E32_RS09820 1998301..1998444 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
E2E32_RS09825 1998549..1999517 - 969 WP_004151446.1 VirK/YbjX family protein -
E2E32_RS09830 1999674..2000327 + 654 WP_002911396.1 protein-serine/threonine phosphatase -
E2E32_RS09835 2000324..2000515 - 192 WP_002911395.1 YebW family protein -
E2E32_RS09840 2000613..2000852 - 240 WP_002911393.1 YebV family protein -
E2E32_RS09845 2000968..2002401 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T120402 NZ_CP037928:1997824-1997926 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT120402 NZ_CP037928:c1997933-1997788 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References