Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 610610..611283 Replicon chromosome
Accession NZ_CP037913
Organism Sphingomonas sp. AAP5

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag E2E30_RS02800 Protein ID WP_133187039.1
Coordinates 610846..611283 (+) Length 146 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag E2E30_RS02795 Protein ID WP_133187037.1
Coordinates 610610..610849 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E2E30_RS02770 605690..606337 + 648 WP_133187031.1 pseudouridine synthase -
E2E30_RS02775 606404..606709 - 306 Protein_551 NAD(P)H-dependent oxidoreductase -
E2E30_RS02780 606888..608342 - 1455 WP_165954438.1 peptidase S41 -
E2E30_RS02785 608556..609977 - 1422 WP_133187035.1 type I glutamate--ammonia ligase -
E2E30_RS02790 610074..610412 - 339 WP_010183375.1 P-II family nitrogen regulator -
E2E30_RS02795 610610..610849 + 240 WP_133187037.1 CopG family transcriptional regulator Antitoxin
E2E30_RS02800 610846..611283 + 438 WP_133187039.1 PIN domain-containing protein Toxin
E2E30_RS02805 611295..612119 - 825 WP_133187041.1 type I methionyl aminopeptidase -
E2E30_RS02810 612186..612941 + 756 WP_133187043.1 competence/damage-inducible protein A -
E2E30_RS02815 612959..613300 + 342 WP_133187045.1 hypothetical protein -
E2E30_RS02825 613843..615342 + 1500 WP_133187049.1 MFS transporter -
E2E30_RS02830 615430..615843 - 414 WP_165954439.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-126)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 146 a.a.        Molecular weight: 15485.79 Da        Isoelectric Point: 8.0040

>T120344 WP_133187039.1 NZ_CP037913:610846-611283 [Sphingomonas sp. AAP5]
MTYLLDVNVLIALIDRRHVNHDVAHRWFSETGHAAWATCPLTENGVLRIVGHPRYANTPGSPAAVVPVLASLCALPGHVF
WPDAISLLDERHVTGAKLFTSAQLTDTYLLALAASRHGKLATLDSRVGGQAVPGGKASLHVIATQ

Download         Length: 438 bp

>T120344 NZ_CP037913:610846-611283 [Sphingomonas sp. AAP5]
ATGACCTATCTGCTGGACGTCAATGTCCTGATCGCGCTGATCGACCGCCGCCACGTCAACCACGACGTGGCGCATCGCTG
GTTTTCGGAGACCGGGCATGCCGCATGGGCAACGTGTCCGCTGACCGAAAACGGCGTGCTGCGGATCGTCGGTCATCCGC
GCTACGCGAATACGCCGGGCTCGCCTGCAGCGGTCGTGCCGGTGCTGGCGAGTCTGTGTGCGCTACCCGGCCATGTGTTC
TGGCCGGATGCTATTTCCCTGCTGGACGAGCGGCACGTCACCGGCGCGAAGCTTTTCACCTCGGCGCAGCTGACCGACAC
CTATCTCCTTGCCTTGGCTGCGAGCCGACATGGGAAGCTCGCAACGCTGGACAGTCGGGTCGGGGGGCAGGCCGTGCCGG
GGGGCAAGGCCTCGCTCCACGTGATTGCGACCCAATAG

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8801.94 Da        Isoelectric Point: 4.5258

>AT120344 WP_133187037.1 NZ_CP037913:610610-610849 [Sphingomonas sp. AAP5]
MRTTLAIDDDVLLVARDLARQQRRSIGEVVSDLARRSLRSEGSDGSSQTMRNGFVLLPVNNPDAVITMEMVNSLRDELE

Download         Length: 240 bp

>AT120344 NZ_CP037913:610610-610849 [Sphingomonas sp. AAP5]
ATGCGCACGACCCTGGCTATCGATGACGACGTTCTCTTGGTTGCGCGCGATCTCGCGCGGCAGCAGCGGCGGAGCATCGG
GGAGGTCGTGTCGGATTTAGCGCGGCGGTCGTTGCGCTCCGAGGGCTCGGACGGATCGTCGCAGACGATGCGCAACGGAT
TTGTCTTGCTGCCGGTGAACAATCCCGACGCGGTCATCACGATGGAGATGGTCAATTCGCTCCGCGACGAGCTCGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References