Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) chpSB/PRK09812-ChpS
Location 4232706..4233301 Replicon chromosome
Accession NZ_CP037903
Organism Escherichia coli strain LHM10-1

Toxin (Protein)


Gene name chpB Uniprot ID -
Locus tag E1J55_RS20580 Protein ID WP_089601988.1
Coordinates 4232706..4233056 (-) Length 117 a.a.

Antitoxin (Protein)


Gene name chpS Uniprot ID -
Locus tag E1J55_RS20585 Protein ID WP_136698564.1
Coordinates 4233050..4233301 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E1J55_RS20560 4228155..4229177 - 1023 WP_122992735.1 ABC transporter permease -
E1J55_RS20565 4229191..4230693 - 1503 WP_136698562.1 sugar ABC transporter ATP-binding protein -
E1J55_RS20570 4230833..4231789 - 957 WP_000265933.1 galactofuranose ABC transporter substrate-binding protein YtfQ -
E1J55_RS20575 4232099..4232629 + 531 WP_000055072.1 inorganic diphosphatase -
E1J55_RS20580 4232706..4233056 - 351 WP_089601988.1 endoribonuclease toxin ChpB Toxin
E1J55_RS20585 4233050..4233301 - 252 WP_136698564.1 type II toxin-antitoxin system antitoxin ChpS Antitoxin
E1J55_RS20590 4233513..4233854 - 342 WP_001219160.1 gamma-glutamylcyclotransferase -
E1J55_RS20595 4233857..4237636 - 3780 WP_136698565.1 autotransporter assembly complex protein TamB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(8-114)

Antitoxin

SpoVT-AbrB domain

(6-49)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12493.41 Da        Isoelectric Point: 5.6219

>T120295 WP_089601988.1 NZ_CP037903:c4233056-4232706 [Escherichia coli]
MVKKSEFERGDIVLVGFDPASGHEQQGAGRPALVLSVQAFNQLGITLVAPITQGGNFARYAGFSVPLHCEEGDVHGVVLV
NQVRMMDLRARLAKRIGLAADEVVEEALLRLQAVVE

Download         Length: 351 bp

>T120295 NZ_CP037903:c4233056-4232706 [Escherichia coli]
ATGGTAAAGAAAAGTGAATTTGAACGGGGAGACATTGTGCTGGTTGGCTTTGATCCAGCAAGCGGCCATGAACAGCAAGG
TGCTGGTCGACCTGCGCTTGTGCTCTCCGTTCAAGCCTTTAATCAACTGGGAATAACGCTGGTGGCCCCCATTACGCAGG
GTGGAAATTTTGCCCGTTATGCCGGATTTAGCGTTCCTTTACATTGCGAAGAAGGCGATGTGCACGGCGTGGTGCTGGTT
AATCAGGTGCGGATGATGGATCTACGCGCCCGGCTGGCAAAGCGTATTGGTCTGGCTGCGGATGAGGTGGTGGAAGAGGC
GTTATTACGCTTGCAGGCGGTGGTGGAATAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9327.69 Da        Isoelectric Point: 4.4201

>AT120295 WP_136698564.1 NZ_CP037903:c4233301-4233050 [Escherichia coli]
MRITIKRWGNSAGMVIPNIVMKELNLQPGQSVEVQVSNNQLILTPISRRYSLDELLAQCDMNAAELSEQDVWGKSTPVGD
EIW

Download         Length: 252 bp

>AT120295 NZ_CP037903:c4233301-4233050 [Escherichia coli]
ATGCGTATTACCATAAAAAGATGGGGGAACAGTGCAGGTATGGTCATTCCCAATATCGTAATGAAAGAACTTAACTTACA
GCCGGGGCAGAGCGTGGAAGTGCAGGTGAGCAACAACCAACTGATTCTGACACCCATCTCCAGGCGCTACTCGCTTGATG
AACTGCTGGCACAGTGTGACATGAACGCCGCGGAACTTAGCGAGCAGGATGTCTGGGGTAAATCCACCCCTGTGGGTGAC
GAAATATGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References