Detailed information of TA system TA120269

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-VagC
• Location: 7965..8590
• Replicon: plasmid PNCS015054 strain 4[5]12:i:-
• Accession: NZ_CP037876
• Organism: Salmonella enterica subsp. enterica serovar 4[5]12:i:- strain PNCS015054

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: E1966_RS01370
• Protein ID: WP_000911322.1
• Coordinates: 8192..8590 (+)
• Length: 133 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: E1966_RS01365
• Protein ID: WP_000450265.1
• Coordinates: 7965..8192 (+)
• Length: 76 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
E1966_RS01365	7965..8192	+	228	WP_000450265.1	toxin-antitoxin system antitoxin VapB	Antitoxin
E1966_RS01370	8192..8590	+	399	WP_000911322.1	tRNA(fMet)-specific endonuclease VapC	Toxin
E1966_RS01375	8599..10761	-	2163	WP_000009318.1	type IV conjugative transfer system coupling protein TraD	-
E1966_RS01380	11138..11869	-	732	WP_000782438.1	complement resistance protein TraT	-
E1966_RS01385	11905..12399	-	495	WP_010999946.1	entry exclusion protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..96545	96545

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Cro/C1-type helix-turn-helix domain (46-89)

Antitoxin

• Toxin HigB-like (13-88)

Sequences

Toxin

Protein

• Length: 133 a.a.
• Molecular weight: 17065.17 Da
• Isoelectric Point: 12.9205

>T120269 WP_000911322.1 NZ_CP037876:8192-8590 [Salmonella enterica subsp. enterica serovar 4,[5],12:i:-]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK

Nucleotide

• Length: 399 bp

>T120269 NZ_CP037876:8192-8590 [Salmonella enterica subsp. enterica serovar 4,[5],12:i:-]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Antitoxin

Protein

• Length: 76 a.a.
• Molecular weight: 9759.25 Da
• Isoelectric Point: 12.6750

>AT120269 WP_000450265.1 NZ_CP037876:7965-8192 [Salmonella enterica subsp. enterica serovar 4,[5],12:i:-]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK

Nucleotide

• Length: 228 bp

>AT120269 NZ_CP037876:7965-8192 [Salmonella enterica subsp. enterica serovar 4,[5],12:i:-]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA