Detailed information of TA system TA120268

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-VagC
• Location: 80857..81482
• Replicon: plasmid PNCS014854 strain 4[5]12:i:-
• Accession: NZ_CP037873
• Organism: Salmonella enterica subsp. enterica serovar 4[5]12:i:- strain PNCS014854

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: E1965_RS00500
• Protein ID: WP_000911322.1
• Coordinates: 80857..81255 (-)
• Length: 133 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: E1965_RS00505
• Protein ID: WP_000450265.1
• Coordinates: 81255..81482 (-)
• Length: 76 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
E1965_RS00485	77048..77542	+	495	WP_010999946.1	entry exclusion protein	-
E1965_RS00490	77578..78309	+	732	WP_000782438.1	complement resistance protein TraT	-
E1965_RS00495	78686..80848	+	2163	WP_000009318.1	type IV conjugative transfer system coupling protein TraD	-
E1965_RS00500	80857..81255	-	399	WP_000911322.1	tRNA(fMet)-specific endonuclease VapC	Toxin
E1965_RS00505	81255..81482	-	228	WP_000450265.1	toxin-antitoxin system antitoxin VapB	Antitoxin

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..93844	93844

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin HigB-like (13-88)

Antitoxin

• Cro/C1-type helix-turn-helix domain (46-89)

Sequences

Toxin

Protein

• Length: 133 a.a.
• Molecular weight: 19592.50 Da
• Isoelectric Point: 5.5500

>T120268 WP_000911322.1 NZ_CP037873:c81255-80857 [Salmonella enterica subsp. enterica serovar 4,[5],12:i:-]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Nucleotide

• Length: 399 bp

>T120268 NZ_CP037873:c81255-80857 [Salmonella enterica subsp. enterica serovar 4,[5],12:i:-]
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Antitoxin

Protein

• Length: 76 a.a.
• Molecular weight: 11203.44 Da
• Isoelectric Point: 5.5500

>AT120268 WP_000450265.1 NZ_CP037873:c81482-81255 [Salmonella enterica subsp. enterica serovar 4,[5],12:i:-]
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Nucleotide

• Length: 228 bp

>AT120268 NZ_CP037873:c81482-81255 [Salmonella enterica subsp. enterica serovar 4,[5],12:i:-]
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