Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 4319056..4319710 Replicon chromosome
Accession NZ_CP037864
Organism Citrobacter sp. LY-1

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag E1B03_RS21735 Protein ID WP_103769062.1
Coordinates 4319056..4319463 (-) Length 136 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag E1B03_RS21740 Protein ID WP_103769061.1
Coordinates 4319444..4319710 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E1B03_RS21715 4314950..4316683 - 1734 WP_133086908.1 single-stranded-DNA-specific exonuclease RecJ -
E1B03_RS21720 4316689..4317402 - 714 WP_103769064.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
E1B03_RS21725 4317426..4318322 - 897 WP_133086909.1 site-specific tyrosine recombinase XerD -
E1B03_RS21730 4318436..4318957 + 522 WP_103769063.1 flavodoxin FldB -
E1B03_RS21735 4319056..4319463 - 408 WP_103769062.1 protein YgfX Toxin
E1B03_RS21740 4319444..4319710 - 267 WP_103769061.1 FAD assembly factor SdhE Antitoxin
E1B03_RS21750 4319967..4320950 + 984 WP_133086910.1 tRNA-modifying protein YgfZ -
E1B03_RS21755 4321081..4321743 - 663 WP_063940912.1 hemolysin III family protein -
E1B03_RS21760 4321907..4322218 - 312 WP_043017509.1 N(4)-acetylcytidine aminohydrolase -
E1B03_RS21765 4322271..4322999 + 729 WP_003838265.1 MurR/RpiR family transcriptional regulator -
E1B03_RS21770 4323120..4324553 + 1434 WP_103769058.1 6-phospho-beta-glucosidase BglA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15863.70 Da        Isoelectric Point: 11.5692

>T120262 WP_103769062.1 NZ_CP037864:c4319463-4319056 [Citrobacter sp. LY-1]
VVQWQSDLRVSWRAQWLSLLIHGLVAVFILLMPWPLSYTPLWLVLLSLVVFDSVRSQRRINACQGEIRLLMNGRLRWQGQ
EWSIVSAPWMVKTGMMLRLRSDAGKRQHLWLAADSMDDAEWRDLRRLILQQAKQG

Download         Length: 408 bp

>T120262 NZ_CP037864:c4319463-4319056 [Citrobacter sp. LY-1]
GTGGTCCAGTGGCAATCTGATTTACGCGTTTCATGGCGCGCGCAGTGGCTATCGCTGCTCATTCATGGGCTGGTCGCGGT
ATTTATTTTATTGATGCCCTGGCCATTGAGCTACACCCCATTATGGCTGGTGCTGCTCTCTCTGGTGGTATTCGATAGCG
TACGTAGCCAGCGTCGAATTAACGCCTGTCAGGGCGAGATTCGACTGTTGATGAACGGTCGTCTGCGTTGGCAAGGGCAG
GAGTGGTCTATCGTTAGCGCACCCTGGATGGTCAAAACGGGCATGATGCTGCGTTTACGTTCCGATGCCGGAAAGCGTCA
GCATTTGTGGCTGGCGGCAGACAGTATGGATGACGCAGAGTGGCGAGATTTGCGACGGTTAATACTGCAGCAGGCGAAGC
AGGGATAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10528.06 Da        Isoelectric Point: 5.1700

>AT120262 WP_103769061.1 NZ_CP037864:c4319710-4319444 [Citrobacter sp. LY-1]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDGLSDEEKRIFIRLLECDDPDLFNWLMNHGKPADAELEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp

>AT120262 NZ_CP037864:c4319710-4319444 [Citrobacter sp. LY-1]
ATGGATATTAACAACAAAGCACGTATTCATTGGGCATGCCGCCGCGGTATGCGCGAGCTGGACATCTCTATCATGCCGTT
TTTCGAACATGAATATGACGGCTTAAGTGACGAAGAAAAACGCATCTTTATCCGTCTGCTAGAATGTGATGATCCAGACT
TATTTAACTGGTTGATGAATCATGGGAAACCAGCTGATGCTGAGCTGGAGCAGATGGTGCGACTTATCCAGACACGGAAT
CGGGAACGTGGTCCAGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References