Detailed information of TA system TA120011

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): parDE/ParE-RHH
• Location: 554702..555245
• Replicon: chromosome
• Accession: NZ_CP037755
• Organism: Pseudocnuella soli strain 17J28-1

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: EPD17_RS02340
• Protein ID: WP_132051439.1
• Coordinates: 554946..555245 (+)
• Length: 100 a.a.

Antitoxin (Protein)

• Gene name: parD
• Uniprot ID: -
• Locus tag: EPD17_RS02335
• Protein ID: WP_132051436.1
• Coordinates: 554702..554953 (+)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EPD17_RS02315	550495..551085	+	591	WP_132051428.1	ATP-binding protein	-
EPD17_RS02320	551082..552746	+	1665	WP_132051430.1	glycosyltransferase family 39 protein	-
EPD17_RS02325	552796..553512	-	717	WP_132051432.1	monofunctional biosynthetic peptidoglycan transglycosylase	-
EPD17_RS02330	553766..554572	+	807	WP_132051434.1	hypothetical protein	-
EPD17_RS02335	554702..554953	+	252	WP_132051436.1	type II toxin-antitoxin system ParD family antitoxin	Antitoxin
EPD17_RS02340	554946..555245	+	300	WP_132051439.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
EPD17_RS02345	555391..556080	-	690	WP_132051441.1	LysE family transporter	-
EPD17_RS02350	556209..557762	-	1554	WP_132051443.1	GH3 auxin-responsive promoter family protein	-
EPD17_RS02355	557923..559095	-	1173	WP_132051445.1	glycosyltransferase family 2 protein	-
EPD17_RS02360	559231..560013	+	783	WP_132051447.1	inositol monophosphatase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-92)

Antitoxin

• Antitoxin ParD (1-79)

Sequences

Toxin

Protein

• Length: 100 a.a.
• Molecular weight: 11733.55 Da
• Isoelectric Point: 5.1718

>T120011 WP_132051439.1 NZ_CP037755:554946-555245 [Pseudocnuella soli]
MPKYFLTQKAVEDLTAIWEYTFETWSERQADKYYAMLAASFEQILEHPEMGKRYPEVDAGLVGLRVGKHIVFYRMMPAND
IEVIRILHQSMDLKSRMEE

Nucleotide

• Length: 300 bp

>T120011 NZ_CP037755:554946-555245 [Pseudocnuella soli]
ATGCCTAAGTATTTTCTTACCCAAAAAGCCGTTGAAGACCTTACTGCAATTTGGGAATATACCTTCGAAACCTGGTCGGA
GCGGCAAGCGGATAAGTATTACGCAATGCTGGCCGCAAGTTTTGAGCAAATCCTGGAGCATCCGGAGATGGGAAAAAGGT
ACCCAGAGGTTGATGCCGGGTTGGTGGGCCTTCGCGTAGGAAAGCACATTGTATTCTACAGAATGATGCCTGCCAATGAC
ATTGAAGTGATCAGGATTCTGCATCAAAGCATGGACCTAAAAAGCCGGATGGAGGAATAG

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9243.30 Da
• Isoelectric Point: 5.6939

>AT120011 WP_132051436.1 NZ_CP037755:554702-554953 [Pseudocnuella soli]
MGRNTSVSLGDYFEDFVENRIAEGRYKNASEVIRAGLRLLEAEENRVAALKHAIIEGINSGIAQDFDADQHLQQLKAAKQ
RNA

Nucleotide

• Length: 252 bp

>AT120011 NZ_CP037755:554702-554953 [Pseudocnuella soli]
ATGGGACGCAATACATCTGTTTCGCTGGGCGACTATTTCGAAGACTTTGTAGAAAATCGAATTGCCGAGGGCAGGTATAA
AAATGCCAGTGAGGTGATCAGGGCGGGATTACGACTTTTGGAAGCAGAGGAAAACCGGGTTGCTGCTTTGAAGCATGCAA
TTATTGAAGGAATAAACAGCGGCATTGCGCAAGACTTTGATGCAGATCAGCACTTGCAACAATTAAAAGCAGCAAAGCAG
CGGAATGCCTAA