Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 488541..489084 Replicon chromosome
Accession NZ_CP037755
Organism Pseudocnuella soli strain 17J28-1

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag EPD17_RS02050 Protein ID WP_132051337.1
Coordinates 488541..488840 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag EPD17_RS02055 Protein ID WP_132051339.1
Coordinates 488830..489084 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EPD17_RS02025 484303..484875 - 573 WP_132051330.1 YkgB family protein -
EPD17_RS02030 484921..485382 - 462 WP_132051331.1 DUF983 domain-containing protein -
EPD17_RS02035 485389..486276 - 888 WP_132051333.1 helix-turn-helix transcriptional regulator -
EPD17_RS02040 486577..487110 + 534 WP_132051335.1 DinB family protein -
EPD17_RS02045 487297..488406 - 1110 WP_132056180.1 amidohydrolase -
EPD17_RS02050 488541..488840 - 300 WP_132051337.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EPD17_RS02055 488830..489084 - 255 WP_132051339.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
EPD17_RS02060 489285..492098 - 2814 WP_132051341.1 DNA polymerase I -
EPD17_RS02065 492483..492671 - 189 WP_132051343.1 hypothetical protein -
EPD17_RS02070 492763..493521 - 759 WP_132051345.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-92)

Antitoxin

Antitoxin ParD

(1-81)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 12014.53 Da        Isoelectric Point: 5.6716

>T120010 WP_132051337.1 NZ_CP037755:c488840-488541 [Pseudocnuella soli]
MRYKISAKAAEDIETIWLYTFENWSLEQADRYVDLIFDEIEYLAANPTSGKDFSQVRKNYRRSKVKSHIVFYRHLENQNE
IEVIRVLHQRMDIETRLDD

Download         Length: 300 bp

>T120010 NZ_CP037755:c488840-488541 [Pseudocnuella soli]
ATGAGATATAAGATTAGTGCTAAAGCGGCAGAAGACATTGAAACCATCTGGCTGTACACTTTTGAGAACTGGTCTCTGGA
ACAGGCAGACAGGTATGTAGACCTGATCTTTGATGAAATCGAATACTTGGCTGCTAATCCAACTTCAGGAAAAGATTTCA
GCCAGGTTCGAAAGAACTACCGTCGCTCCAAGGTAAAATCACACATTGTATTCTATCGACACCTCGAAAACCAAAACGAA
ATCGAAGTCATCAGGGTATTGCACCAGCGCATGGACATAGAAACCAGGCTCGATGATTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9658.02 Da        Isoelectric Point: 9.5407

>AT120010 WP_132051339.1 NZ_CP037755:c489084-488830 [Pseudocnuella soli]
MAKNTSILLGEYFDKFINDQVQSGRYNSASEVVRAALRLFEEEERKKGELVKELVKGEKSGFVHGFDRKAFVKSLHTKHV
KDEI

Download         Length: 255 bp

>AT120010 NZ_CP037755:c489084-488830 [Pseudocnuella soli]
ATGGCAAAGAATACATCAATTCTTTTGGGCGAGTATTTCGATAAGTTCATCAATGACCAAGTGCAAAGTGGACGTTACAA
TTCGGCCAGCGAGGTAGTGCGGGCAGCACTGCGCCTCTTTGAAGAAGAGGAGCGGAAAAAAGGTGAGCTGGTAAAAGAGT
TGGTGAAAGGCGAAAAGTCTGGATTTGTCCATGGCTTCGACAGAAAAGCGTTTGTCAAATCCCTTCACACCAAACATGTG
AAGGATGAGATATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References