Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-virA/YafQ(toxin)
Location 335584..336142 Replicon chromosome
Accession NZ_CP037747
Organism Campylobacter helveticus strain 2013D-9613

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag A0073_RS01920 Protein ID WP_115588761.1
Coordinates 335912..336142 (+) Length 77 a.a.

Antitoxin (Protein)


Gene name virA Uniprot ID -
Locus tag A0073_RS01915 Protein ID WP_082199810.1
Coordinates 335584..335874 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A0073_RS01890 331593..332186 - 594 WP_131936407.1 C39 family peptidase -
A0073_RS01895 332171..333025 - 855 WP_131936409.1 HmcD domain-containing protein -
A0073_RS01900 333158..334006 - 849 WP_131937829.1 hypothetical protein -
A0073_RS01905 334081..334305 - 225 WP_131936411.1 mobilization protein -
A0073_RS01910 334520..335488 + 969 Protein_377 recombinase XerC -
A0073_RS01915 335584..335874 + 291 WP_082199810.1 hypothetical protein Antitoxin
A0073_RS01920 335912..336142 + 231 WP_115588761.1 type II toxin-antitoxin system YafQ family toxin Toxin
A0073_RS01925 336249..336359 - 111 Protein_380 polymerase -
A0073_RS01930 336910..337431 - 522 WP_131936413.1 inorganic diphosphatase -
A0073_RS01935 337441..337716 - 276 WP_131936415.1 DUF4410 domain-containing protein -
A0073_RS01940 337924..338499 - 576 WP_082199807.1 adenylate kinase -
A0073_RS01945 338496..340247 - 1752 WP_082199806.1 aspartate--tRNA ligase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 254977..336504 81527


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(3-74)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 77 a.a.        Molecular weight: 9241.75 Da        Isoelectric Point: 9.4069

>T120008 WP_115588761.1 NZ_CP037747:335912-336142 [Campylobacter helveticus]
MVRKQNWDIKAIKKCVEDLAILDILPQSYKDHALKGDLKNFRECHIFGDLVIIYKRDDREVNYYRIGRHQDLFKKY

Download         Length: 231 bp

>T120008 NZ_CP037747:335912-336142 [Campylobacter helveticus]
TTGGTTAGAAAACAAAATTGGGATATTAAGGCAATTAAAAAGTGTGTTGAAGATTTAGCAATATTAGATATTTTACCACA
AAGTTACAAAGACCACGCCCTAAAAGGTGATTTGAAAAATTTTAGAGAGTGCCATATTTTTGGCGATTTAGTTATAATCT
ACAAGAGAGATGATAGGGAAGTTAATTATTACCGCATAGGCAGACACCAAGATTTATTTAAAAAATATTAA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 11295.94 Da        Isoelectric Point: 8.3162

>AT120008 WP_082199810.1 NZ_CP037747:335584-335874 [Campylobacter helveticus]
MYDYAKYENATPKQLVYALSLAEKRAEKLSLQLKENEEFFKFLQKKLRNSFSTKKIKKEELTKETKAILAKDEPTPYTNF
DRLLEAVDKEIEAENA

Download         Length: 291 bp

>AT120008 NZ_CP037747:335584-335874 [Campylobacter helveticus]
ATGTATGATTATGCAAAATACGAAAATGCAACTCCAAAACAATTGGTTTATGCACTTTCTTTAGCAGAAAAAAGGGCGGA
AAAACTAAGTTTGCAATTAAAAGAAAATGAAGAGTTTTTTAAATTTTTGCAAAAAAAACTAAGAAATTCTTTTAGCACTA
AAAAAATAAAAAAAGAAGAACTAACAAAGGAAACTAAAGCAATTTTAGCAAAAGATGAACCAACACCTTATACTAACTTT
GATAGACTATTAGAAGCTGTTGATAAAGAGATTGAAGCTGAAAATGCGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References