Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /DUF1778(antitoxin)
Location 1649081..1649842 Replicon chromosome
Accession NZ_CP037745
Organism Rheinheimera sp. D18

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag E0Z06_RS07790 Protein ID WP_132583462.1
Coordinates 1649081..1649596 (-) Length 172 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag E0Z06_RS07795 Protein ID WP_207903190.1
Coordinates 1649597..1649842 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E0Z06_RS07770 1644904..1645608 + 705 WP_132583456.1 orotidine-5'-phosphate decarboxylase -
E0Z06_RS07775 1645626..1647365 + 1740 WP_132583458.1 potassium/proton antiporter -
E0Z06_RS07780 1647716..1648018 - 303 WP_132583460.1 hypothetical protein -
E0Z06_RS07785 1648075..1649056 - 982 Protein_1507 site-specific integrase -
E0Z06_RS07790 1649081..1649596 - 516 WP_132583462.1 GNAT family N-acetyltransferase Toxin
E0Z06_RS07795 1649597..1649842 - 246 WP_207903190.1 DUF1778 domain-containing protein Antitoxin
E0Z06_RS07800 1650142..1651317 + 1176 WP_132586739.1 DNA-binding protein -
E0Z06_RS07805 1651464..1652000 + 537 WP_132583464.1 hypothetical protein -
E0Z06_RS07810 1652595..1653119 - 525 WP_132583466.1 NUDIX domain-containing protein -
E0Z06_RS07815 1653196..1654050 - 855 WP_132583468.1 universal stress protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1641436..1664588 23152


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Vibrio phage ICP1, Orf50

(1-74)


Sequences

Toxin        


Download         Length: 172 a.a.        Molecular weight: 18455.58 Da        Isoelectric Point: 9.5019

>T120005 WP_132583462.1 NZ_CP037745:c1649596-1649081 [Rheinheimera sp. D18]
MSLSSAFVLIDAAAHDLKGFDCGKPSLNDYLSRFAVRNSSLGLSRTWVLTELVAQGKAPVAAYFTLASSTVTRELLPSQP
KSLPAYPVPVVLLARLGVSLTQQGRQLGAKTLVQALRTALELTDTGLPALGVVLDVLDEAALKFYQHMGLFTPLTDQPMR
LFVPMSTLRQL

Download         Length: 516 bp

>T120005 NZ_CP037745:c1649596-1649081 [Rheinheimera sp. D18]
TTGTCTCTCTCTTCAGCTTTTGTTCTGATTGACGCTGCAGCGCATGATTTGAAAGGCTTTGACTGCGGTAAACCCAGCCT
CAATGACTACCTGAGCCGGTTTGCTGTTCGTAACAGCTCCCTGGGGTTAAGTCGTACCTGGGTTTTGACGGAGCTCGTTG
CTCAAGGCAAGGCTCCGGTTGCAGCTTATTTTACGTTAGCAAGCAGTACTGTCACTCGTGAATTATTGCCTTCTCAGCCC
AAATCGCTGCCAGCCTATCCGGTGCCTGTTGTACTTCTTGCCAGGCTCGGTGTTTCTCTCACTCAGCAAGGACGTCAACT
GGGGGCTAAAACCCTGGTTCAGGCGCTTCGTACCGCTCTTGAATTGACAGACACGGGGCTACCAGCGCTTGGTGTGGTAC
TGGACGTTCTGGATGAAGCAGCGCTGAAGTTTTACCAGCATATGGGCCTATTTACTCCATTGACGGATCAGCCGATGCGT
CTTTTTGTGCCGATGAGCACGTTACGTCAGCTTTAA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8828.03 Da        Isoelectric Point: 5.0050

>AT120005 WP_207903190.1 NZ_CP037745:c1649842-1649597 [Rheinheimera sp. D18]
MRVDAETKQLAERAAAALGCASLTEFMVRLIRDNAPQILQSQSAIELTSAQFDHFQQVCEAAAAPHQRLKDAAALLDKEG
F

Download         Length: 246 bp

>AT120005 NZ_CP037745:c1649842-1649597 [Rheinheimera sp. D18]
ATGCGGGTCGATGCAGAAACCAAGCAGCTGGCAGAGCGAGCTGCTGCAGCGCTTGGCTGTGCGTCGTTGACTGAATTTAT
GGTTCGCCTTATCCGGGATAATGCGCCTCAGATTTTGCAGTCTCAATCAGCCATTGAACTTACATCAGCCCAGTTTGATC
ACTTCCAGCAGGTATGTGAAGCGGCGGCGGCCCCCCATCAGCGGCTTAAAGACGCTGCGGCTCTACTGGATAAAGAGGGA
TTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References