Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2010075..2010220 Replicon chromosome
Accession NZ_CP037742
Organism Klebsiella pneumoniae strain ST23

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2010111..2010213 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2010075..2010220 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E1A84_RS09715 2005206..2007266 + 2061 WP_004151449.1 oligopeptidase B -
E1A84_RS09720 2007270..2007929 - 660 WP_002911407.1 exodeoxyribonuclease X -
E1A84_RS09725 2008008..2008238 - 231 WP_002911406.1 DNA polymerase III subunit theta -
E1A84_RS09730 2008351..2008725 + 375 WP_004151448.1 CopC domain-containing protein YobA -
E1A84_RS09735 2008729..2009598 + 870 WP_014907333.1 copper homeostasis membrane protein CopD -
E1A84_RS09740 2009615..2009953 + 339 WP_002911404.1 YebY family protein -
- 2010075..2010220 - 146 - - Antitoxin
- 2010111..2010213 + 103 - - Toxin
E1A84_RS28500 2010588..2010731 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
E1A84_RS09750 2010836..2011804 - 969 WP_014907334.1 VirK/YbjX family protein -
E1A84_RS09755 2011961..2012614 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
E1A84_RS09760 2012611..2012802 - 192 WP_002911395.1 YebW family protein -
E1A84_RS09765 2012900..2013139 - 240 WP_002911393.1 YebV family protein -
E1A84_RS09770 2013255..2014688 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T119985 NZ_CP037742:2010111-2010213 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT119985 NZ_CP037742:c2010220-2010075 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References