Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4861685..4861953 Replicon chromosome
Accession NZ_CP037449
Organism Escherichia coli strain ATCC 25922

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4861723..4861825 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4861685..4861953 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E0708_RS23130 4858842..4860281 + 1440 WP_001704100.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
E0708_RS23135 4860399..4860635 + 237 WP_001295499.1 DUF1480 family protein -
E0708_RS23140 4860740..4860931 + 192 WP_001317886.1 YebW family protein -
E0708_RS23145 4860932..4861588 - 657 WP_000812743.1 protein-serine/threonine phosphatase -
- 4861685..4861953 + 269 - - Antitoxin
- 4861723..4861825 - 103 - - Toxin
E0708_RS23150 4861983..4862324 - 342 WP_000984819.1 YebY family protein -
E0708_RS23155 4862337..4863209 - 873 WP_000879311.1 copper homeostasis membrane protein CopD -
E0708_RS23160 4863213..4863587 - 375 WP_000168747.1 CopC domain-containing protein YobA -
E0708_RS23165 4863726..4863956 + 231 WP_000916763.1 DNA polymerase III subunit theta -
E0708_RS23170 4864059..4864715 + 657 WP_000011644.1 carbon-nitrogen hydrolase family protein -
E0708_RS23175 4864739..4865401 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T119974 NZ_CP037449:c4861825-4861723 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT119974 NZ_CP037449:4861685-4861953 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References