Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 2821394..2822015 Replicon chromosome
Accession NZ_CP036532
Organism Roseitalea porphyridii strain MA7-20

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag E0E05_RS13730 Protein ID WP_131617232.1
Coordinates 2821394..2821690 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag E0E05_RS13735 Protein ID WP_131617233.1
Coordinates 2821704..2822015 (+) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E0E05_RS13710 2817512..2818138 + 627 WP_131617228.1 hypothetical protein -
E0E05_RS13715 2818256..2819194 + 939 WP_131617229.1 ribose-phosphate pyrophosphokinase -
E0E05_RS13720 2819383..2819895 + 513 WP_131617230.1 pseudoazurin -
E0E05_RS13725 2819914..2821251 - 1338 WP_131617231.1 chromate efflux transporter -
E0E05_RS13730 2821394..2821690 + 297 WP_131617232.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
E0E05_RS13735 2821704..2822015 + 312 WP_131617233.1 putative addiction module antidote protein Antitoxin
E0E05_RS13740 2822037..2822726 - 690 WP_131617234.1 SDR family NAD(P)-dependent oxidoreductase -
E0E05_RS13745 2823012..2823698 + 687 WP_131617235.1 50S ribosomal protein L25/general stress protein Ctc -
E0E05_RS13750 2823726..2824481 + 756 WP_131617236.1 aminoacyl-tRNA hydrolase -
E0E05_RS13755 2824525..2825061 - 537 WP_210215716.1 LuxR family transcriptional regulator -
E0E05_RS13760 2825078..2825671 - 594 WP_131617237.1 cytochrome b/b6 domain-containing protein -
E0E05_RS13765 2825671..2826129 - 459 WP_131617238.1 PepSY domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(13-91)

Antitoxin

Uncharacterized protein HI1420

(2-93)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11618.45 Da        Isoelectric Point: 10.4178

>T119940 WP_131617232.1 NZ_CP036532:2821394-2821690 [Roseitalea porphyridii]
MIEVRQTREFARWLHTLRDRRAREKIAIRLARIEATGNLGDYKRIDEIAELRIAYGPGYRLYFTFRGDVLIILLCGGDKK
SQQRDIRRARQIAEELDL

Download         Length: 297 bp

>T119940 NZ_CP036532:2821394-2821690 [Roseitalea porphyridii]
ATGATCGAGGTGCGCCAGACGCGCGAGTTCGCCCGATGGCTGCACACACTTAGGGATCGCCGCGCGCGGGAGAAGATCGC
CATCCGTCTGGCCCGGATCGAGGCCACCGGCAATCTCGGCGACTACAAGCGGATCGACGAGATCGCCGAACTGCGCATCG
CCTACGGACCGGGCTACAGGCTGTATTTCACGTTTCGGGGCGATGTCCTGATCATCCTGCTGTGCGGCGGCGACAAGAAG
AGCCAGCAGCGCGACATACGCCGCGCAAGACAGATCGCGGAAGAACTGGACCTGTAG

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 11090.43 Da        Isoelectric Point: 5.1457

>AT119940 WP_131617233.1 NZ_CP036532:2821704-2822015 [Roseitalea porphyridii]
MTKTEPFDAARYLESEEGQRDLIADALESGDPAYLKHALNIVARARGMTAVARDAGVAREALYRALSENGDPRLSTLMGV
FKALDVQLTARTADHVAGARTSD

Download         Length: 312 bp

>AT119940 NZ_CP036532:2821704-2822015 [Roseitalea porphyridii]
ATGACGAAGACGGAGCCGTTCGACGCTGCCCGCTATCTGGAAAGCGAGGAAGGCCAGCGTGACCTGATCGCCGATGCGCT
GGAAAGCGGCGATCCGGCATATCTCAAGCACGCGCTCAACATCGTGGCCCGGGCGCGCGGAATGACCGCCGTCGCCCGGG
ACGCCGGCGTCGCCCGGGAAGCCCTTTACCGGGCACTGAGCGAGAACGGCGATCCCCGCCTGTCCACGCTGATGGGCGTC
TTCAAGGCGCTCGACGTGCAACTGACGGCCCGCACGGCCGATCATGTCGCGGGCGCGCGCACTTCCGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References