Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | PumAB/upstrm_HI1419-dnstrm_HI1420 |
Location | 2821394..2822015 | Replicon | chromosome |
Accession | NZ_CP036532 | ||
Organism | Roseitalea porphyridii strain MA7-20 |
Toxin (Protein)
Gene name | PumA | Uniprot ID | - |
Locus tag | E0E05_RS13730 | Protein ID | WP_131617232.1 |
Coordinates | 2821394..2821690 (+) | Length | 99 a.a. |
Antitoxin (Protein)
Gene name | PumB | Uniprot ID | - |
Locus tag | E0E05_RS13735 | Protein ID | WP_131617233.1 |
Coordinates | 2821704..2822015 (+) | Length | 104 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
E0E05_RS13710 | 2817512..2818138 | + | 627 | WP_131617228.1 | hypothetical protein | - |
E0E05_RS13715 | 2818256..2819194 | + | 939 | WP_131617229.1 | ribose-phosphate pyrophosphokinase | - |
E0E05_RS13720 | 2819383..2819895 | + | 513 | WP_131617230.1 | pseudoazurin | - |
E0E05_RS13725 | 2819914..2821251 | - | 1338 | WP_131617231.1 | chromate efflux transporter | - |
E0E05_RS13730 | 2821394..2821690 | + | 297 | WP_131617232.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
E0E05_RS13735 | 2821704..2822015 | + | 312 | WP_131617233.1 | putative addiction module antidote protein | Antitoxin |
E0E05_RS13740 | 2822037..2822726 | - | 690 | WP_131617234.1 | SDR family NAD(P)-dependent oxidoreductase | - |
E0E05_RS13745 | 2823012..2823698 | + | 687 | WP_131617235.1 | 50S ribosomal protein L25/general stress protein Ctc | - |
E0E05_RS13750 | 2823726..2824481 | + | 756 | WP_131617236.1 | aminoacyl-tRNA hydrolase | - |
E0E05_RS13755 | 2824525..2825061 | - | 537 | WP_210215716.1 | LuxR family transcriptional regulator | - |
E0E05_RS13760 | 2825078..2825671 | - | 594 | WP_131617237.1 | cytochrome b/b6 domain-containing protein | - |
E0E05_RS13765 | 2825671..2826129 | - | 459 | WP_131617238.1 | PepSY domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 99 a.a. Molecular weight: 11618.45 Da Isoelectric Point: 10.4178
>T119940 WP_131617232.1 NZ_CP036532:2821394-2821690 [Roseitalea porphyridii]
MIEVRQTREFARWLHTLRDRRAREKIAIRLARIEATGNLGDYKRIDEIAELRIAYGPGYRLYFTFRGDVLIILLCGGDKK
SQQRDIRRARQIAEELDL
MIEVRQTREFARWLHTLRDRRAREKIAIRLARIEATGNLGDYKRIDEIAELRIAYGPGYRLYFTFRGDVLIILLCGGDKK
SQQRDIRRARQIAEELDL
Download Length: 297 bp
>T119940 NZ_CP036532:2821394-2821690 [Roseitalea porphyridii]
ATGATCGAGGTGCGCCAGACGCGCGAGTTCGCCCGATGGCTGCACACACTTAGGGATCGCCGCGCGCGGGAGAAGATCGC
CATCCGTCTGGCCCGGATCGAGGCCACCGGCAATCTCGGCGACTACAAGCGGATCGACGAGATCGCCGAACTGCGCATCG
CCTACGGACCGGGCTACAGGCTGTATTTCACGTTTCGGGGCGATGTCCTGATCATCCTGCTGTGCGGCGGCGACAAGAAG
AGCCAGCAGCGCGACATACGCCGCGCAAGACAGATCGCGGAAGAACTGGACCTGTAG
ATGATCGAGGTGCGCCAGACGCGCGAGTTCGCCCGATGGCTGCACACACTTAGGGATCGCCGCGCGCGGGAGAAGATCGC
CATCCGTCTGGCCCGGATCGAGGCCACCGGCAATCTCGGCGACTACAAGCGGATCGACGAGATCGCCGAACTGCGCATCG
CCTACGGACCGGGCTACAGGCTGTATTTCACGTTTCGGGGCGATGTCCTGATCATCCTGCTGTGCGGCGGCGACAAGAAG
AGCCAGCAGCGCGACATACGCCGCGCAAGACAGATCGCGGAAGAACTGGACCTGTAG
Antitoxin
Download Length: 104 a.a. Molecular weight: 11090.43 Da Isoelectric Point: 5.1457
>AT119940 WP_131617233.1 NZ_CP036532:2821704-2822015 [Roseitalea porphyridii]
MTKTEPFDAARYLESEEGQRDLIADALESGDPAYLKHALNIVARARGMTAVARDAGVAREALYRALSENGDPRLSTLMGV
FKALDVQLTARTADHVAGARTSD
MTKTEPFDAARYLESEEGQRDLIADALESGDPAYLKHALNIVARARGMTAVARDAGVAREALYRALSENGDPRLSTLMGV
FKALDVQLTARTADHVAGARTSD
Download Length: 312 bp
>AT119940 NZ_CP036532:2821704-2822015 [Roseitalea porphyridii]
ATGACGAAGACGGAGCCGTTCGACGCTGCCCGCTATCTGGAAAGCGAGGAAGGCCAGCGTGACCTGATCGCCGATGCGCT
GGAAAGCGGCGATCCGGCATATCTCAAGCACGCGCTCAACATCGTGGCCCGGGCGCGCGGAATGACCGCCGTCGCCCGGG
ACGCCGGCGTCGCCCGGGAAGCCCTTTACCGGGCACTGAGCGAGAACGGCGATCCCCGCCTGTCCACGCTGATGGGCGTC
TTCAAGGCGCTCGACGTGCAACTGACGGCCCGCACGGCCGATCATGTCGCGGGCGCGCGCACTTCCGATTGA
ATGACGAAGACGGAGCCGTTCGACGCTGCCCGCTATCTGGAAAGCGAGGAAGGCCAGCGTGACCTGATCGCCGATGCGCT
GGAAAGCGGCGATCCGGCATATCTCAAGCACGCGCTCAACATCGTGGCCCGGGCGCGCGGAATGACCGCCGTCGCCCGGG
ACGCCGGCGTCGCCCGGGAAGCCCTTTACCGGGCACTGAGCGAGAACGGCGATCCCCGCCTGTCCACGCTGATGGGCGTC
TTCAAGGCGCTCGACGTGCAACTGACGGCCCGCACGGCCGATCATGTCGCGGGCGCGCGCACTTCCGATTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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