Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/HTH_26(antitoxin)
Location 2512849..2513431 Replicon chromosome
Accession NZ_CP036532
Organism Roseitalea porphyridii strain MA7-20

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag E0E05_RS12275 Protein ID WP_131616975.1
Coordinates 2513183..2513431 (-) Length 83 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag E0E05_RS12270 Protein ID WP_210215706.1
Coordinates 2512849..2513175 (-) Length 109 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E0E05_RS12250 2507965..2509026 + 1062 WP_210215705.1 extracellular solute-binding protein -
E0E05_RS12255 2509542..2511179 - 1638 WP_131618022.1 iron ABC transporter permease -
E0E05_RS12260 2511456..2512622 + 1167 WP_131616972.1 aromatic ring-hydroxylating dioxygenase subunit alpha -
E0E05_RS12265 2512609..2512842 + 234 WP_131616973.1 hypothetical protein -
E0E05_RS12270 2512849..2513175 - 327 WP_210215706.1 helix-turn-helix domain-containing protein Antitoxin
E0E05_RS12275 2513183..2513431 - 249 WP_131616975.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
E0E05_RS12280 2513473..2514180 - 708 WP_131618023.1 DUF1045 domain-containing protein -
E0E05_RS12285 2514658..2514918 + 261 WP_039723052.1 DUF4212 domain-containing protein -
E0E05_RS12290 2514948..2516735 + 1788 WP_131616976.1 cation acetate symporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-79)

Antitoxin

Cro/C1-type helix-turn-helix domain

(56-107)


Sequences

Toxin        


Download         Length: 83 a.a.        Molecular weight: 9172.87 Da        Isoelectric Point: 11.2302

>T119937 WP_131616975.1 NZ_CP036532:c2513431-2513183 [Roseitalea porphyridii]
MKPIVYLPGAEKTLRRLPRNVAMRIIRKVEAYATDPASLANNVKTLKGRDGIRLRVGDWRVIMRDGVVLEVLAVGPRGSV
YD

Download         Length: 249 bp

>T119937 NZ_CP036532:c2513431-2513183 [Roseitalea porphyridii]
ATGAAGCCGATCGTCTATCTTCCCGGTGCCGAGAAGACGTTGCGACGGCTTCCGCGGAACGTTGCCATGCGTATCATCAG
GAAGGTGGAGGCGTACGCCACCGATCCGGCGTCGCTGGCCAACAACGTCAAGACATTGAAGGGCCGGGACGGTATCAGGC
TCAGGGTCGGCGATTGGCGCGTCATCATGAGGGACGGGGTTGTCCTGGAAGTGCTCGCCGTGGGGCCGCGCGGCAGCGTC
TACGATTGA

Antitoxin


Download         Length: 109 a.a.        Molecular weight: 11725.41 Da        Isoelectric Point: 4.3170

>AT119937 WP_210215706.1 NZ_CP036532:c2513175-2512849 [Roseitalea porphyridii]
MKMITIPEAEYEALVAAKEDLEDILAYDKAIEEGGEGIPHPFMVRLIEGDSPVAVYREWRGLTQAALSEASGVNRVQIAE
IEAGRKTGSVKTLRKLADALGVTIDDLV

Download         Length: 327 bp

>AT119937 NZ_CP036532:c2513175-2512849 [Roseitalea porphyridii]
ATGAAGATGATCACCATTCCCGAGGCGGAGTATGAGGCGCTCGTCGCCGCCAAGGAGGATCTCGAGGACATTCTCGCATA
CGACAAGGCGATCGAAGAGGGTGGGGAGGGTATCCCGCACCCATTCATGGTTCGTCTCATCGAGGGTGACAGCCCTGTTG
CGGTCTACCGCGAATGGCGCGGCCTGACGCAGGCGGCGCTGTCGGAGGCTTCCGGCGTCAATCGCGTGCAGATCGCCGAG
ATCGAGGCGGGCCGGAAGACCGGCTCGGTGAAGACGCTCAGGAAGCTCGCCGACGCGCTCGGCGTGACGATCGACGATCT
GGTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References