Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/HTH_26(antitoxin) |
Location | 2512849..2513431 | Replicon | chromosome |
Accession | NZ_CP036532 | ||
Organism | Roseitalea porphyridii strain MA7-20 |
Toxin (Protein)
Gene name | relE | Uniprot ID | - |
Locus tag | E0E05_RS12275 | Protein ID | WP_131616975.1 |
Coordinates | 2513183..2513431 (-) | Length | 83 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | - |
Locus tag | E0E05_RS12270 | Protein ID | WP_210215706.1 |
Coordinates | 2512849..2513175 (-) | Length | 109 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
E0E05_RS12250 | 2507965..2509026 | + | 1062 | WP_210215705.1 | extracellular solute-binding protein | - |
E0E05_RS12255 | 2509542..2511179 | - | 1638 | WP_131618022.1 | iron ABC transporter permease | - |
E0E05_RS12260 | 2511456..2512622 | + | 1167 | WP_131616972.1 | aromatic ring-hydroxylating dioxygenase subunit alpha | - |
E0E05_RS12265 | 2512609..2512842 | + | 234 | WP_131616973.1 | hypothetical protein | - |
E0E05_RS12270 | 2512849..2513175 | - | 327 | WP_210215706.1 | helix-turn-helix domain-containing protein | Antitoxin |
E0E05_RS12275 | 2513183..2513431 | - | 249 | WP_131616975.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
E0E05_RS12280 | 2513473..2514180 | - | 708 | WP_131618023.1 | DUF1045 domain-containing protein | - |
E0E05_RS12285 | 2514658..2514918 | + | 261 | WP_039723052.1 | DUF4212 domain-containing protein | - |
E0E05_RS12290 | 2514948..2516735 | + | 1788 | WP_131616976.1 | cation acetate symporter | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 83 a.a. Molecular weight: 9172.87 Da Isoelectric Point: 11.2302
>T119937 WP_131616975.1 NZ_CP036532:c2513431-2513183 [Roseitalea porphyridii]
MKPIVYLPGAEKTLRRLPRNVAMRIIRKVEAYATDPASLANNVKTLKGRDGIRLRVGDWRVIMRDGVVLEVLAVGPRGSV
YD
MKPIVYLPGAEKTLRRLPRNVAMRIIRKVEAYATDPASLANNVKTLKGRDGIRLRVGDWRVIMRDGVVLEVLAVGPRGSV
YD
Download Length: 249 bp
>T119937 NZ_CP036532:c2513431-2513183 [Roseitalea porphyridii]
ATGAAGCCGATCGTCTATCTTCCCGGTGCCGAGAAGACGTTGCGACGGCTTCCGCGGAACGTTGCCATGCGTATCATCAG
GAAGGTGGAGGCGTACGCCACCGATCCGGCGTCGCTGGCCAACAACGTCAAGACATTGAAGGGCCGGGACGGTATCAGGC
TCAGGGTCGGCGATTGGCGCGTCATCATGAGGGACGGGGTTGTCCTGGAAGTGCTCGCCGTGGGGCCGCGCGGCAGCGTC
TACGATTGA
ATGAAGCCGATCGTCTATCTTCCCGGTGCCGAGAAGACGTTGCGACGGCTTCCGCGGAACGTTGCCATGCGTATCATCAG
GAAGGTGGAGGCGTACGCCACCGATCCGGCGTCGCTGGCCAACAACGTCAAGACATTGAAGGGCCGGGACGGTATCAGGC
TCAGGGTCGGCGATTGGCGCGTCATCATGAGGGACGGGGTTGTCCTGGAAGTGCTCGCCGTGGGGCCGCGCGGCAGCGTC
TACGATTGA
Antitoxin
Download Length: 109 a.a. Molecular weight: 11725.41 Da Isoelectric Point: 4.3170
>AT119937 WP_210215706.1 NZ_CP036532:c2513175-2512849 [Roseitalea porphyridii]
MKMITIPEAEYEALVAAKEDLEDILAYDKAIEEGGEGIPHPFMVRLIEGDSPVAVYREWRGLTQAALSEASGVNRVQIAE
IEAGRKTGSVKTLRKLADALGVTIDDLV
MKMITIPEAEYEALVAAKEDLEDILAYDKAIEEGGEGIPHPFMVRLIEGDSPVAVYREWRGLTQAALSEASGVNRVQIAE
IEAGRKTGSVKTLRKLADALGVTIDDLV
Download Length: 327 bp
>AT119937 NZ_CP036532:c2513175-2512849 [Roseitalea porphyridii]
ATGAAGATGATCACCATTCCCGAGGCGGAGTATGAGGCGCTCGTCGCCGCCAAGGAGGATCTCGAGGACATTCTCGCATA
CGACAAGGCGATCGAAGAGGGTGGGGAGGGTATCCCGCACCCATTCATGGTTCGTCTCATCGAGGGTGACAGCCCTGTTG
CGGTCTACCGCGAATGGCGCGGCCTGACGCAGGCGGCGCTGTCGGAGGCTTCCGGCGTCAATCGCGTGCAGATCGCCGAG
ATCGAGGCGGGCCGGAAGACCGGCTCGGTGAAGACGCTCAGGAAGCTCGCCGACGCGCTCGGCGTGACGATCGACGATCT
GGTCTGA
ATGAAGATGATCACCATTCCCGAGGCGGAGTATGAGGCGCTCGTCGCCGCCAAGGAGGATCTCGAGGACATTCTCGCATA
CGACAAGGCGATCGAAGAGGGTGGGGAGGGTATCCCGCACCCATTCATGGTTCGTCTCATCGAGGGTGACAGCCCTGTTG
CGGTCTACCGCGAATGGCGCGGCCTGACGCAGGCGGCGCTGTCGGAGGCTTCCGGCGTCAATCGCGTGCAGATCGCCGAG
ATCGAGGCGGGCCGGAAGACCGGCTCGGTGAAGACGCTCAGGAAGCTCGCCGACGCGCTCGGCGTGACGATCGACGATCT
GGTCTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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