Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/HTH_26(antitoxin)
Location 2512849..2513431 Replicon chromosome
Accession NZ_CP036532
Organism Roseitalea porphyridii strain MA7-20

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag E0E05_RS12275 Protein ID WP_131616975.1
Coordinates 2513183..2513431 (-) Length 83 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag E0E05_RS12270 Protein ID WP_210215706.1
Coordinates 2512849..2513175 (-) Length 109 a.a.

Genomic Context

E0E05_RS12250E0E05_RS12260E0E05_RS12265E0E05_RS12285E0E05_RS12290E0E05_RS12255E0E05_RS12270E0E05_RS12275E0E05_RS12280
Location: 2507965..2509026 (1062 bp)
Type: Others
Protein ID: WP_210215705.1
Location: 2511456..2512622 (1167 bp)
Type: Others
Protein ID: WP_131616972.1
Location: 2512609..2512842 (234 bp)
Type: Others
Protein ID: WP_131616973.1
Location: 2514658..2514918 (261 bp)
Type: Others
Protein ID: WP_039723052.1
Location: 2514948..2516735 (1788 bp)
Type: Others
Protein ID: WP_131616976.1
Location: 2509542..2511179 (1638 bp)
Type: Others
Protein ID: WP_131618022.1
Location: 2512849..2513175 (327 bp)
Type: Antitoxin
Protein ID: WP_210215706.1
Location: 2513183..2513431 (249 bp)
Type: Toxin
Protein ID: WP_131616975.1
Location: 2513473..2514180 (708 bp)
Type: Others
Protein ID: WP_131618023.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
E0E05_RS122502507965..2509026+1062WP_210215705.1extracellular solute-binding protein-
E0E05_RS122552509542..2511179-1638WP_131618022.1iron ABC transporter permease-
E0E05_RS122602511456..2512622+1167WP_131616972.1aromatic ring-hydroxylating dioxygenase subunit alpha-
E0E05_RS122652512609..2512842+234WP_131616973.1hypothetical protein-
E0E05_RS122702512849..2513175-327WP_210215706.1helix-turn-helix domain-containing proteinAntitoxin
E0E05_RS122752513183..2513431-249WP_131616975.1type II toxin-antitoxin system RelE/ParE family toxinToxin
E0E05_RS122802513473..2514180-708WP_131618023.1DUF1045 domain-containing protein-
E0E05_RS122852514658..2514918+261WP_039723052.1DUF4212 domain-containing protein-
E0E05_RS122902514948..2516735+1788WP_131616976.1cation acetate symporter-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-79)

Antitoxin

Cro/C1-type helix-turn-helix domain

(56-107)


Sequences

Toxin        


Download         Length: 83 a.a.        Molecular weight: 9172.87 Da        Isoelectric Point: 11.2302

>T119937 WP_131616975.1 NZ_CP036532:c2513431-2513183 [Roseitalea porphyridii]
MKPIVYLPGAEKTLRRLPRNVAMRIIRKVEAYATDPASLANNVKTLKGRDGIRLRVGDWRVIMRDGVVLEVLAVGPRGSV
YD

Download         Length: 249 bp

>T119937 NZ_CP036532:c2513431-2513183 [Roseitalea porphyridii]
ATGAAGCCGATCGTCTATCTTCCCGGTGCCGAGAAGACGTTGCGACGGCTTCCGCGGAACGTTGCCATGCGTATCATCAG
GAAGGTGGAGGCGTACGCCACCGATCCGGCGTCGCTGGCCAACAACGTCAAGACATTGAAGGGCCGGGACGGTATCAGGC
TCAGGGTCGGCGATTGGCGCGTCATCATGAGGGACGGGGTTGTCCTGGAAGTGCTCGCCGTGGGGCCGCGCGGCAGCGTC
TACGATTGA

Antitoxin


Download         Length: 109 a.a.        Molecular weight: 11725.41 Da        Isoelectric Point: 4.3170

>AT119937 WP_210215706.1 NZ_CP036532:c2513175-2512849 [Roseitalea porphyridii]
MKMITIPEAEYEALVAAKEDLEDILAYDKAIEEGGEGIPHPFMVRLIEGDSPVAVYREWRGLTQAALSEASGVNRVQIAE
IEAGRKTGSVKTLRKLADALGVTIDDLV

Download         Length: 327 bp

>AT119937 NZ_CP036532:c2513175-2512849 [Roseitalea porphyridii]
ATGAAGATGATCACCATTCCCGAGGCGGAGTATGAGGCGCTCGTCGCCGCCAAGGAGGATCTCGAGGACATTCTCGCATA
CGACAAGGCGATCGAAGAGGGTGGGGAGGGTATCCCGCACCCATTCATGGTTCGTCTCATCGAGGGTGACAGCCCTGTTG
CGGTCTACCGCGAATGGCGCGGCCTGACGCAGGCGGCGCTGTCGGAGGCTTCCGGCGTCAATCGCGTGCAGATCGCCGAG
ATCGAGGCGGGCCGGAAGACCGGCTCGGTGAAGACGCTCAGGAAGCTCGCCGACGCGCTCGGCGTGACGATCGACGATCT
GGTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References