Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/VapC-StbC |
| Location | 333319..333974 | Replicon | chromosome |
| Accession | NZ_CP036532 | ||
| Organism | Roseitalea porphyridii strain MA7-20 | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | - |
| Locus tag | E0E05_RS01630 | Protein ID | WP_131615109.1 |
| Coordinates | 333319..333729 (-) | Length | 137 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | - |
| Locus tag | E0E05_RS01635 | Protein ID | WP_131615110.1 |
| Coordinates | 333726..333974 (-) | Length | 83 a.a. |
Genomic Context
Location: 330080..330739 (660 bp)
Type: Others
Protein ID: WP_131615106.1
Type: Others
Protein ID: WP_131615106.1
Location: 336546..337520 (975 bp)
Type: Others
Protein ID: WP_131615113.1
Type: Others
Protein ID: WP_131615113.1
Location: 337604..338233 (630 bp)
Type: Others
Protein ID: WP_039722501.1
Type: Others
Protein ID: WP_039722501.1
Location: 338348..338875 (528 bp)
Type: Others
Protein ID: WP_131615114.1
Type: Others
Protein ID: WP_131615114.1
Location: 328597..329766 (1170 bp)
Type: Others
Protein ID: WP_210215742.1
Type: Others
Protein ID: WP_210215742.1
Location: 331060..331977 (918 bp)
Type: Others
Protein ID: WP_131615107.1
Type: Others
Protein ID: WP_131615107.1
Location: 332068..333309 (1242 bp)
Type: Others
Protein ID: WP_131615108.1
Type: Others
Protein ID: WP_131615108.1
Location: 333319..333729 (411 bp)
Type: Toxin
Protein ID: WP_131615109.1
Type: Toxin
Protein ID: WP_131615109.1
Location: 333726..333974 (249 bp)
Type: Antitoxin
Protein ID: WP_131615110.1
Type: Antitoxin
Protein ID: WP_131615110.1
Location: 334041..335618 (1578 bp)
Type: Others
Protein ID: WP_131615111.1
Type: Others
Protein ID: WP_131615111.1
Location: 335623..336399 (777 bp)
Type: Others
Protein ID: WP_131615112.1
Type: Others
Protein ID: WP_131615112.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| E0E05_RS01610 | 328597..329766 | - | 1170 | WP_210215742.1 | twin-arginine translocation pathway signal protein | - |
| E0E05_RS01615 | 330080..330739 | + | 660 | WP_131615106.1 | peroxiredoxin | - |
| E0E05_RS01620 | 331060..331977 | - | 918 | WP_131615107.1 | pirin family protein | - |
| E0E05_RS01625 | 332068..333309 | - | 1242 | WP_131615108.1 | bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC | - |
| E0E05_RS01630 | 333319..333729 | - | 411 | WP_131615109.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
| E0E05_RS01635 | 333726..333974 | - | 249 | WP_131615110.1 | hypothetical protein | Antitoxin |
| E0E05_RS01640 | 334041..335618 | - | 1578 | WP_131615111.1 | 2-polyprenylphenol 6-hydroxylase | - |
| E0E05_RS01645 | 335623..336399 | - | 777 | WP_131615112.1 | bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE | - |
| E0E05_RS01650 | 336546..337520 | + | 975 | WP_131615113.1 | adenosine deaminase | - |
| E0E05_RS01655 | 337604..338233 | + | 630 | WP_039722501.1 | uracil phosphoribosyltransferase | - |
| E0E05_RS01660 | 338348..338875 | + | 528 | WP_131615114.1 | TIGR02281 family clan AA aspartic protease | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 137 a.a. Molecular weight: 14564.52 Da Isoelectric Point: 4.7013
>T119936 WP_131615109.1 NZ_CP036532:c333729-333319 [Roseitalea porphyridii]
VRGFVVDTSALICILFDEPGALAFAQAIADEDRCAISTASVLEGHSVMIRRRIPDGAERLAGLVADLRLEVAAFDARQLE
TAIAAYRQYGRGTGHDADLNLGDCFSYALARTRNLPLLFKGDDFVHTDIASALPAG
VRGFVVDTSALICILFDEPGALAFAQAIADEDRCAISTASVLEGHSVMIRRRIPDGAERLAGLVADLRLEVAAFDARQLE
TAIAAYRQYGRGTGHDADLNLGDCFSYALARTRNLPLLFKGDDFVHTDIASALPAG
Download Length: 411 bp
>T119936 NZ_CP036532:c333729-333319 [Roseitalea porphyridii]
GTGAGGGGGTTTGTCGTCGATACATCGGCCCTCATCTGCATCCTGTTCGACGAGCCCGGCGCGCTCGCGTTCGCCCAAGC
AATCGCCGACGAGGACCGTTGCGCCATCTCGACCGCATCGGTGCTGGAGGGCCACAGCGTGATGATCAGGCGCCGCATAC
CAGACGGGGCCGAACGATTGGCGGGTCTTGTTGCCGATCTTCGTCTCGAGGTGGCGGCGTTCGACGCCCGGCAACTGGAG
ACGGCGATCGCGGCCTATCGCCAGTATGGGCGCGGGACCGGCCATGATGCTGATCTCAACCTCGGCGACTGCTTTTCCTA
CGCGCTCGCCAGGACGCGAAACCTGCCGCTCCTGTTCAAGGGCGACGATTTCGTCCATACCGACATCGCATCGGCCCTTC
CGGCCGGCTGA
GTGAGGGGGTTTGTCGTCGATACATCGGCCCTCATCTGCATCCTGTTCGACGAGCCCGGCGCGCTCGCGTTCGCCCAAGC
AATCGCCGACGAGGACCGTTGCGCCATCTCGACCGCATCGGTGCTGGAGGGCCACAGCGTGATGATCAGGCGCCGCATAC
CAGACGGGGCCGAACGATTGGCGGGTCTTGTTGCCGATCTTCGTCTCGAGGTGGCGGCGTTCGACGCCCGGCAACTGGAG
ACGGCGATCGCGGCCTATCGCCAGTATGGGCGCGGGACCGGCCATGATGCTGATCTCAACCTCGGCGACTGCTTTTCCTA
CGCGCTCGCCAGGACGCGAAACCTGCCGCTCCTGTTCAAGGGCGACGATTTCGTCCATACCGACATCGCATCGGCCCTTC
CGGCCGGCTGA
Antitoxin
Download Length: 83 a.a. Molecular weight: 9491.73 Da Isoelectric Point: 7.0194
>AT119936 WP_131615110.1 NZ_CP036532:c333974-333726 [Roseitalea porphyridii]
MATLTIRNLDEEVKRDIRRAAAERGVSMEQEARDRLARPARHENAEPGKVSAEEILRRYARRPDGPFDLKGMTDRMWDEG
LL
MATLTIRNLDEEVKRDIRRAAAERGVSMEQEARDRLARPARHENAEPGKVSAEEILRRYARRPDGPFDLKGMTDRMWDEG
LL
Download Length: 249 bp
>AT119936 NZ_CP036532:c333974-333726 [Roseitalea porphyridii]
ATGGCCACGCTGACGATCAGGAATCTCGATGAAGAGGTCAAGCGCGACATCCGCCGCGCGGCCGCCGAACGCGGGGTCTC
CATGGAGCAGGAGGCGCGGGACCGTCTGGCGAGGCCAGCCCGCCACGAGAACGCCGAGCCCGGCAAGGTCAGTGCCGAGG
AAATCCTGCGCCGTTACGCGCGCAGACCCGACGGGCCTTTCGATCTCAAAGGGATGACCGACCGAATGTGGGACGAAGGT
CTGCTGTGA
ATGGCCACGCTGACGATCAGGAATCTCGATGAAGAGGTCAAGCGCGACATCCGCCGCGCGGCCGCCGAACGCGGGGTCTC
CATGGAGCAGGAGGCGCGGGACCGTCTGGCGAGGCCAGCCCGCCACGAGAACGCCGAGCCCGGCAAGGTCAGTGCCGAGG
AAATCCTGCGCCGTTACGCGCGCAGACCCGACGGGCCTTTCGATCTCAAAGGGATGACCGACCGAATGTGGGACGAAGGT
CTGCTGTGA