Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 333319..333974 Replicon chromosome
Accession NZ_CP036532
Organism Roseitalea porphyridii strain MA7-20

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag E0E05_RS01630 Protein ID WP_131615109.1
Coordinates 333319..333729 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag E0E05_RS01635 Protein ID WP_131615110.1
Coordinates 333726..333974 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E0E05_RS01610 328597..329766 - 1170 WP_210215742.1 twin-arginine translocation pathway signal protein -
E0E05_RS01615 330080..330739 + 660 WP_131615106.1 peroxiredoxin -
E0E05_RS01620 331060..331977 - 918 WP_131615107.1 pirin family protein -
E0E05_RS01625 332068..333309 - 1242 WP_131615108.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
E0E05_RS01630 333319..333729 - 411 WP_131615109.1 type II toxin-antitoxin system VapC family toxin Toxin
E0E05_RS01635 333726..333974 - 249 WP_131615110.1 hypothetical protein Antitoxin
E0E05_RS01640 334041..335618 - 1578 WP_131615111.1 2-polyprenylphenol 6-hydroxylase -
E0E05_RS01645 335623..336399 - 777 WP_131615112.1 bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE -
E0E05_RS01650 336546..337520 + 975 WP_131615113.1 adenosine deaminase -
E0E05_RS01655 337604..338233 + 630 WP_039722501.1 uracil phosphoribosyltransferase -
E0E05_RS01660 338348..338875 + 528 WP_131615114.1 TIGR02281 family clan AA aspartic protease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-128)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 14564.52 Da        Isoelectric Point: 4.7013

>T119936 WP_131615109.1 NZ_CP036532:c333729-333319 [Roseitalea porphyridii]
VRGFVVDTSALICILFDEPGALAFAQAIADEDRCAISTASVLEGHSVMIRRRIPDGAERLAGLVADLRLEVAAFDARQLE
TAIAAYRQYGRGTGHDADLNLGDCFSYALARTRNLPLLFKGDDFVHTDIASALPAG

Download         Length: 411 bp

>T119936 NZ_CP036532:c333729-333319 [Roseitalea porphyridii]
GTGAGGGGGTTTGTCGTCGATACATCGGCCCTCATCTGCATCCTGTTCGACGAGCCCGGCGCGCTCGCGTTCGCCCAAGC
AATCGCCGACGAGGACCGTTGCGCCATCTCGACCGCATCGGTGCTGGAGGGCCACAGCGTGATGATCAGGCGCCGCATAC
CAGACGGGGCCGAACGATTGGCGGGTCTTGTTGCCGATCTTCGTCTCGAGGTGGCGGCGTTCGACGCCCGGCAACTGGAG
ACGGCGATCGCGGCCTATCGCCAGTATGGGCGCGGGACCGGCCATGATGCTGATCTCAACCTCGGCGACTGCTTTTCCTA
CGCGCTCGCCAGGACGCGAAACCTGCCGCTCCTGTTCAAGGGCGACGATTTCGTCCATACCGACATCGCATCGGCCCTTC
CGGCCGGCTGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9491.73 Da        Isoelectric Point: 7.0194

>AT119936 WP_131615110.1 NZ_CP036532:c333974-333726 [Roseitalea porphyridii]
MATLTIRNLDEEVKRDIRRAAAERGVSMEQEARDRLARPARHENAEPGKVSAEEILRRYARRPDGPFDLKGMTDRMWDEG
LL

Download         Length: 249 bp

>AT119936 NZ_CP036532:c333974-333726 [Roseitalea porphyridii]
ATGGCCACGCTGACGATCAGGAATCTCGATGAAGAGGTCAAGCGCGACATCCGCCGCGCGGCCGCCGAACGCGGGGTCTC
CATGGAGCAGGAGGCGCGGGACCGTCTGGCGAGGCCAGCCCGCCACGAGAACGCCGAGCCCGGCAAGGTCAGTGCCGAGG
AAATCCTGCGCCGTTACGCGCGCAGACCCGACGGGCCTTTCGATCTCAAAGGGATGACCGACCGAATGTGGGACGAAGGT
CTGCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References