Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 140370..141028 Replicon plasmid p_unnamed1
Accession NZ_CP036516
Organism Lichenihabitans psoromatis strain PAMC 29148

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag EY713_RS22290 Protein ID WP_131120277.1
Coordinates 140370..140804 (-) Length 145 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag EY713_RS22295 Protein ID WP_131120279.1
Coordinates 140801..141028 (-) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EY713_RS22265 136241..136646 + 406 Protein_135 transposase -
EY713_RS22270 136643..136885 + 243 WP_131120269.1 IS66 family insertion sequence element accessory protein TnpB -
EY713_RS22275 137079..138524 - 1446 WP_131120271.1 IS1182 family transposase -
EY713_RS22280 138570..139016 - 447 WP_131120273.1 GNAT family N-acetyltransferase -
EY713_RS22285 139149..139685 - 537 WP_165491254.1 LysR family transcriptional regulator substrate-binding protein -
EY713_RS22290 140370..140804 - 435 WP_131120277.1 PIN domain-containing protein Toxin
EY713_RS22295 140801..141028 - 228 WP_131120279.1 CopG family transcriptional regulator Antitoxin
EY713_RS22300 141058..142047 - 990 Protein_142 DUF2493 domain-containing protein -
EY713_RS22305 142382..142978 - 597 WP_131120281.1 toprim domain-containing protein -
EY713_RS22310 143217..143468 + 252 WP_131120283.1 hypothetical protein -
EY713_RS22320 143755..144710 - 956 Protein_145 DUF1738 domain-containing protein -
EY713_RS22325 145207..145785 + 579 WP_131120332.1 DUF2384 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..152258 152258


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-131)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 145 a.a.        Molecular weight: 15456.68 Da        Isoelectric Point: 6.8431

>T119929 WP_131120277.1 NZ_CP036516:c140804-140370 [Lichenihabitans psoromatis]
VTFLLDVNVLVALIDPGHVAHDAAHRWFEEEGATDWATCPLTENGVIRIVGHPRYPNTPGSPAAVAAIVIKLRGLPGHSF
WKDDLSLVDSDRINVARIFTSAQVTDTYLLALAGAHGGVLTTLDRRLSTAAVKNGKGALHYMLP

Download         Length: 435 bp

>T119929 NZ_CP036516:c140804-140370 [Lichenihabitans psoromatis]
GTGACCTTTCTGCTGGACGTCAATGTTCTGGTCGCGTTGATCGACCCGGGGCATGTGGCGCACGATGCCGCGCATCGGTG
GTTCGAAGAGGAAGGGGCCACCGACTGGGCCACCTGCCCTCTGACCGAGAACGGCGTCATCCGCATCGTCGGCCACCCGA
GGTACCCGAACACGCCCGGCTCACCGGCGGCCGTCGCGGCAATCGTCATCAAGCTCCGCGGCCTGCCGGGGCACTCCTTT
TGGAAGGACGATCTCAGTCTTGTGGATTCGGACCGGATCAATGTCGCTCGGATTTTCACCTCGGCACAGGTGACGGACAC
CTATCTTCTCGCTTTGGCCGGTGCACACGGCGGCGTGCTGACGACGTTGGATCGGCGTCTGTCGACAGCGGCAGTAAAAA
ACGGGAAGGGCGCACTTCACTACATGCTGCCTTAG

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8243.58 Da        Isoelectric Point: 8.8949

>AT119929 WP_131120279.1 NZ_CP036516:c141028-140801 [Lichenihabitans psoromatis]
MRTTLAIDDDVLVAAKAMARQQNRSLGEIISGLARKSLGWPEPRSERNGIPLLRVKPDAPLVTLEIVNALRDEVP

Download         Length: 228 bp

>AT119929 NZ_CP036516:c141028-140801 [Lichenihabitans psoromatis]
TTGAGAACGACCTTGGCGATTGATGATGACGTTCTCGTGGCGGCCAAGGCGATGGCGCGTCAGCAGAACCGAAGCCTCGG
CGAGATCATATCGGGCTTGGCGCGCAAGTCGCTGGGTTGGCCGGAGCCGCGTTCCGAGCGGAACGGAATTCCCCTGCTCC
GCGTCAAACCTGACGCACCGCTGGTGACGCTCGAGATCGTCAACGCGCTTCGCGACGAGGTACCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References