Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 94237..94889 Replicon plasmid p_unnamed1
Accession NZ_CP036516
Organism Lichenihabitans psoromatis strain PAMC 29148

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag EY713_RS22030 Protein ID WP_131120208.1
Coordinates 94497..94889 (+) Length 131 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag EY713_RS22025 Protein ID WP_131120206.1
Coordinates 94237..94488 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EY713_RS22015 91264..93378 - 2115 WP_131120204.1 ParB/RepB/Spo0J family partition protein -
EY713_RS22020 93719..94013 + 295 Protein_85 hypothetical protein -
EY713_RS22025 94237..94488 + 252 WP_131120206.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
EY713_RS22030 94497..94889 + 393 WP_131120208.1 type II toxin-antitoxin system VapC family toxin Toxin
EY713_RS22035 95296..96248 - 953 Protein_88 DUF1738 domain-containing protein -
EY713_RS22040 96705..97037 + 333 WP_131120319.1 MbcA/ParS/Xre antitoxin family protein -
EY713_RS22045 97034..97567 + 534 WP_131120210.1 RES domain-containing protein -
EY713_RS22050 98368..99564 - 1197 WP_165491250.1 IS701 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..152258 152258


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-120)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 131 a.a.        Molecular weight: 13905.06 Da        Isoelectric Point: 6.7205

>T119928 WP_131120208.1 NZ_CP036516:94497-94889 [Lichenihabitans psoromatis]
MLDTNIVSDMMRNPRGKVADHIARVGEENLCISIITAAELRYGAAKSGSSRILERVEAILARVPVLPLAPPADAHYGGIR
AELEAAGRPIGPNDLLIAAHATALGAIMITANVAEFRRVRGLEVRDWTAD

Download         Length: 393 bp

>T119928 NZ_CP036516:94497-94889 [Lichenihabitans psoromatis]
ATGCTGGACACCAACATCGTGTCCGACATGATGCGCAACCCTCGGGGCAAGGTCGCGGACCACATTGCCAGGGTGGGCGA
AGAGAACCTCTGCATCAGCATCATCACGGCGGCGGAGCTGCGGTATGGGGCGGCGAAAAGCGGATCGAGCCGCATTCTGG
AGAGGGTCGAAGCCATCCTGGCGCGGGTTCCGGTCCTGCCTCTGGCACCGCCGGCGGATGCGCATTACGGCGGCATTCGT
GCCGAGCTCGAAGCCGCGGGCCGTCCGATCGGACCCAACGACCTTTTGATCGCGGCTCATGCCACCGCGCTGGGCGCCAT
CATGATCACGGCGAACGTCGCCGAGTTTCGGCGCGTGCGAGGCCTCGAAGTCCGGGACTGGACGGCCGATTAG

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9306.66 Da        Isoelectric Point: 4.7223

>AT119928 WP_131120206.1 NZ_CP036516:94237-94488 [Lichenihabitans psoromatis]
MPDAAPRPRQVRLFRNNRSQAIRIPVEFELPGTEAVISRDGDRLIIAPVHQSKLLDLLAGWQPLDDEFPDVDAGLPPLRD
VTL

Download         Length: 252 bp

>AT119928 NZ_CP036516:94237-94488 [Lichenihabitans psoromatis]
ATGCCGGATGCAGCGCCTCGACCCCGCCAGGTCCGACTCTTTCGCAACAATCGGAGCCAGGCCATACGCATCCCTGTCGA
GTTCGAGCTGCCGGGCACCGAAGCCGTCATCAGTCGCGATGGCGACCGGCTCATCATCGCGCCCGTGCACCAGAGCAAGC
TCTTGGACCTTCTCGCCGGCTGGCAGCCGCTCGATGACGAATTTCCCGATGTCGATGCAGGCTTACCGCCGCTTCGCGAC
GTGACGCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References