Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 83592..84250 Replicon plasmid p_unnamed1
Accession NZ_CP036516
Organism Lichenihabitans psoromatis strain PAMC 29148

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag EY713_RS21990 Protein ID WP_131120196.1
Coordinates 83592..84026 (-) Length 145 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag EY713_RS21995 Protein ID WP_131120198.1
Coordinates 84023..84250 (-) Length 76 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EY713_RS21970 78641..79870 - 1230 WP_131120190.1 replication initiation protein RepC -
EY713_RS21975 80091..81110 - 1020 WP_131120192.1 plasmid partitioning protein RepB -
EY713_RS21980 81113..82318 - 1206 WP_131120194.1 plasmid partitioning protein RepA -
EY713_RS21985 82754..83074 - 321 WP_131120188.1 DUF736 family protein -
EY713_RS21990 83592..84026 - 435 WP_131120196.1 PIN domain-containing protein Toxin
EY713_RS21995 84023..84250 - 228 WP_131120198.1 ribbon-helix-helix domain-containing protein Antitoxin
EY713_RS22000 84336..85265 - 930 WP_170314124.1 DUF2493 domain-containing protein -
EY713_RS22005 85618..86682 - 1065 WP_131120317.1 toprim domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..152258 152258


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(4-128)

Antitoxin


No domain identified.



Sequences


Toxin        


Download         Length: 145 a.a.        Molecular weight: 15511.84 Da        Isoelectric Point: 7.5202

>T119927 WP_131120196.1 NZ_CP036516:c84026-83592 [Lichenihabitans psoromatis]
MTFLLDVNVLIALIDASHVAHEMAHHWFERTGSMDWATCPLTENGVIRIVGHPNYPNTPGSPAAVAPIVAKLRLLPGHSF
WPDDLSLVGSDRVEASRILTSAQVTDTYLLALARAHSGQLATLDRRLSFAAVKGGKAALRQIGP

Download         Length: 435 bp

>T119927 NZ_CP036516:c84026-83592 [Lichenihabitans psoromatis]
TTGACGTTCCTGCTCGACGTGAATGTGCTCATCGCGCTCATCGATGCTTCCCACGTCGCTCATGAAATGGCCCATCATTG
GTTCGAGCGGACAGGCTCCATGGATTGGGCCACCTGCCCCCTGACCGAGAACGGGGTCATTCGGATCGTCGGGCATCCCA
ACTACCCGAACACGCCGGGATCGCCGGCTGCCGTTGCGCCGATCGTCGCCAAACTGCGCCTGCTGCCCGGGCATAGCTTC
TGGCCGGACGATCTCAGTCTGGTCGGGTCGGACCGCGTCGAGGCGTCTCGCATTTTGACCTCGGCTCAGGTGACGGACAC
TTACCTGCTCGCCTTGGCGAGGGCGCACAGCGGTCAGTTAGCGACTCTGGATCGCCGGTTGTCGTTCGCGGCCGTGAAGG
GCGGCAAGGCTGCCCTGCGCCAGATCGGGCCGTAG

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8127.27 Da        Isoelectric Point: 5.7809

>AT119927 WP_131120198.1 NZ_CP036516:c84250-84023 [Lichenihabitans psoromatis]
VRTTLSIDDDVLVAAKAMAEQENRSLGAIISDLARKALRRPAPHSERNGIQLLSTRPDAAPVTLEIVNALRDDLP

Download         Length: 228 bp

>AT119927 NZ_CP036516:c84250-84023 [Lichenihabitans psoromatis]
GTGAGAACGACTCTCTCGATCGACGATGACGTTCTTGTGGCCGCCAAGGCGATGGCTGAGCAAGAGAATAGAAGCCTGGG
AGCAATCATTTCCGATCTGGCGCGTAAGGCACTTCGGCGGCCTGCGCCGCATTCGGAGCGGAACGGCATCCAACTCTTGA
GTACCCGACCCGACGCCGCACCCGTGACGCTCGAGATCGTCAACGCTCTTCGTGATGATCTCCCTTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References