Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 4829582..4830144 Replicon chromosome
Accession NZ_CP036498
Organism Rhodopseudomonas sp. SK50-23

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag RPMA_RS23130 Protein ID WP_211910009.1
Coordinates 4829582..4829953 (-) Length 124 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag RPMA_RS23135 Protein ID WP_211910010.1
Coordinates 4829950..4830144 (-) Length 65 a.a.

Genomic Context

RPMA_RS23115RPMA_RS23095RPMA_RS23100RPMA_RS23105RPMA_RS23110RPMA_RS23120RPMA_RS23125RPMA_RS23130RPMA_RS23135RPMA_RS23140RPMA_RS23145RPMA_RS23150RPMA_RS23155
Location: 4827827..4828561 (735 bp)
Type: Others
Protein ID: WP_211910006.1
Location: 4824636..4825520 (885 bp)
Type: Others
Protein ID: WP_211910003.1
Location: 4825517..4826626 (1110 bp)
Type: Others
Protein ID: WP_211910004.1
Location: 4826629..4827237 (609 bp)
Type: Others
Protein ID: WP_211910005.1
Location: 4827240..4827653 (414 bp)
Type: Others
Protein ID: WP_249225361.1
Location: 4828577..4829044 (468 bp)
Type: Others
Protein ID: WP_211910007.1
Location: 4829128..4829529 (402 bp)
Type: Others
Protein ID: WP_249225751.1
Location: 4829582..4829953 (372 bp)
Type: Toxin
Protein ID: WP_211910009.1
Location: 4829950..4830144 (195 bp)
Type: Antitoxin
Protein ID: WP_211910010.1
Location: 4830207..4831253 (1047 bp)
Type: Others
Protein ID: WP_211910011.1
Location: 4831421..4832038 (618 bp)
Type: Others
Protein ID: WP_211910012.1
Location: 4832250..4832774 (525 bp)
Type: Others
Protein ID: WP_211910013.1
Location: 4833597..4834343 (747 bp)
Type: Others
Protein ID: WP_211910014.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
RPMA_RS23095 (RPMA_22830)4824636..4825520-885WP_211910003.1alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase PhnJ-
RPMA_RS23100 (RPMA_22835)4825517..4826626-1110WP_211910004.1carbon-phosphorus lyase complex subunit PhnI-
RPMA_RS23105 (RPMA_22840)4826629..4827237-609WP_211910005.1phosphonate C-P lyase system protein PhnH-
RPMA_RS23110 (RPMA_22845)4827240..4827653-414WP_249225361.1phosphonate C-P lyase system protein PhnG-
RPMA_RS23115 (RPMA_22850)4827827..4828561+735WP_211910006.1phosphonate metabolism transcriptional regulator PhnF-
RPMA_RS23120 (RPMA_22855)4828577..4829044-468WP_211910007.1nuclear transport factor 2 family protein-
RPMA_RS23125 (RPMA_22860)4829128..4829529-402WP_249225751.1tol-pal system-associated acyl-CoA thioesterase-
RPMA_RS23130 (RPMA_22865)4829582..4829953-372WP_211910009.1type II toxin-antitoxin system VapC family toxinToxin
RPMA_RS23135 (RPMA_22870)4829950..4830144-195WP_211910010.1type II toxin-antitoxin system VapB family antitoxinAntitoxin
RPMA_RS23140 (RPMA_22875)4830207..4831253-1047WP_211910011.1Holliday junction branch migration DNA helicase RuvB-
RPMA_RS23145 (RPMA_22880)4831421..4832038-618WP_211910012.1Holliday junction branch migration protein RuvA-
RPMA_RS23150 (RPMA_22885)4832250..4832774-525WP_211910013.1crossover junction endodeoxyribonuclease RuvC-
RPMA_RS23155 (RPMA_22890)4833597..4834343-747WP_211910014.1YebC/PmpR family DNA-binding transcriptional regulator-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-46)


Sequences

Toxin        


Download         Length: 124 a.a.        Molecular weight: 13783.12 Da        Isoelectric Point: 6.8803

>T119893 WP_211910009.1 NZ_CP036498:c4829953-4829582 [Rhodopseudomonas sp. SK50-23]
MILPDTSVWIDHFRGGEKLLAPLLRSEDLLLHPFVIGELAVGPLPRRADTIRRLKLQIQAPIIDPPDVLAFIEQHALFGR
GLSYVDVQLLASVHALVNTRLWTTDKRLDIAADQLGIAYKSKE

Download         Length: 372 bp

>T119893 NZ_CP036498:c4829953-4829582 [Rhodopseudomonas sp. SK50-23]
ATGATCCTCCCCGATACATCGGTCTGGATCGATCATTTTCGCGGCGGCGAAAAGCTGCTGGCGCCGCTTCTTCGCAGCGA
AGATCTGTTGTTGCATCCTTTTGTCATCGGGGAGCTCGCGGTCGGGCCTCTGCCGCGTCGCGCAGACACGATCAGGCGAC
TTAAGCTGCAGATACAGGCTCCGATCATTGATCCACCCGACGTCCTTGCTTTTATCGAGCAACACGCGCTTTTCGGTCGT
GGCCTCAGCTATGTTGATGTTCAGCTGCTAGCCTCGGTTCATGCGCTCGTGAATACCCGGTTATGGACAACGGACAAGCG
GCTTGATATCGCGGCCGATCAGCTCGGGATTGCGTACAAGTCCAAGGAATAG

Antitoxin


Download         Length: 65 a.a.        Molecular weight: 7220.08 Da        Isoelectric Point: 4.7361

>AT119893 WP_211910010.1 NZ_CP036498:c4830144-4829950 [Rhodopseudomonas sp. SK50-23]
MNTTVVVDGKLLDQAREYSDALENSELVQEALRAFIRREAARHLADLGGSMPDAEAPPRRRWEP

Download         Length: 195 bp

>AT119893 NZ_CP036498:c4830144-4829950 [Rhodopseudomonas sp. SK50-23]
ATGAATACAACTGTTGTTGTGGACGGTAAATTACTCGATCAGGCGCGCGAATATAGCGATGCGTTGGAGAACTCCGAGCT
CGTCCAAGAAGCTCTGAGAGCATTCATTCGGCGCGAGGCCGCTAGGCATCTTGCTGACCTTGGCGGCTCGATGCCCGATG
CCGAAGCGCCGCCTCGTCGTAGATGGGAGCCATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References