Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1(toxin)
Location 3233994..3234568 Replicon chromosome
Accession NZ_CP036498
Organism Rhodopseudomonas sp. SK50-23

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag RPMA_RS15335 Protein ID WP_211908315.1
Coordinates 3233994..3234359 (-) Length 122 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag RPMA_RS15340 Protein ID WP_211908317.1
Coordinates 3234353..3234568 (-) Length 72 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RPMA_RS15325 (RPMA_15180) 3232136..3233320 - 1185 WP_211908311.1 CmpA/NrtA family ABC transporter substrate-binding protein -
RPMA_RS15330 (RPMA_15185) 3233317..3233904 - 588 WP_211908313.1 ANTAR domain-containing protein -
RPMA_RS15335 (RPMA_15190) 3233994..3234359 - 366 WP_211908315.1 type II toxin-antitoxin system VapC family toxin Toxin
RPMA_RS15340 (RPMA_15195) 3234353..3234568 - 216 WP_211908317.1 ribbon-helix-helix protein, CopG family Antitoxin
RPMA_RS15345 (RPMA_15200) 3234840..3236168 + 1329 WP_211908319.1 30S ribosomal protein S12 methylthiotransferase RimO -
RPMA_RS15350 (RPMA_15205) 3236350..3237324 - 975 WP_211908322.1 quinone oxidoreductase -
RPMA_RS15355 (RPMA_15210) 3237390..3238112 - 723 WP_211908324.1 TerC family protein -
RPMA_RS15360 (RPMA_15215) 3238109..3238843 - 735 WP_211908326.1 phosphatidylcholine synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-106)

Antitoxin

Ribbon-helix-helix protein, CopG

(7-39)


Sequences

Toxin        


Download         Length: 122 a.a.        Molecular weight: 13594.72 Da        Isoelectric Point: 7.2052

>T119892 WP_211908315.1 NZ_CP036498:c3234359-3233994 [Rhodopseudomonas sp. SK50-23]
MVGALFDTNILIDHLNAVPQAREEIARFENRAISIITWMEVMVGAKRDLVEQTRRFLGGFEVIALDNAIADRAVTLRQTH
RIKLPDAVIWATAQTAARLLVTRNTKDFPPDDPGIRTPYAL

Download         Length: 366 bp

>T119892 NZ_CP036498:c3234359-3233994 [Rhodopseudomonas sp. SK50-23]
ATGGTAGGCGCGCTATTCGACACCAACATCCTCATCGACCATCTGAACGCCGTGCCCCAGGCCCGCGAAGAGATCGCGCG
TTTCGAAAATCGCGCCATCAGCATCATTACCTGGATGGAGGTGATGGTGGGCGCGAAACGCGATCTGGTCGAGCAGACCC
GCCGCTTTCTCGGCGGCTTCGAAGTCATCGCCCTGGACAACGCGATTGCCGATCGTGCAGTGACGTTGCGGCAGACGCAT
CGCATCAAGCTGCCCGATGCGGTGATCTGGGCAACGGCGCAGACCGCCGCACGTCTGCTGGTGACCCGCAATACGAAGGA
CTTTCCGCCCGACGATCCCGGAATTCGCACGCCCTATGCTTTATAG

Antitoxin


Download         Length: 72 a.a.        Molecular weight: 8124.22 Da        Isoelectric Point: 9.7761

>AT119892 WP_211908317.1 NZ_CP036498:c3234568-3234353 [Rhodopseudomonas sp. SK50-23]
MRALIDMSDAQVKALDALAKRGRQSRAALIRAAIDDYLQRHHRAQVEDGFGLWGKREVDGLAYQDKVRSEW

Download         Length: 216 bp

>AT119892 NZ_CP036498:c3234568-3234353 [Rhodopseudomonas sp. SK50-23]
ATGCGTGCTTTGATCGATATGAGCGACGCCCAGGTGAAAGCCTTGGACGCGCTGGCGAAACGAGGGAGGCAGTCTCGTGC
TGCGCTGATCCGGGCGGCGATCGACGACTATCTCCAACGCCATCATCGCGCCCAGGTGGAGGACGGTTTCGGCCTGTGGG
GCAAACGTGAGGTCGATGGTCTGGCCTATCAGGACAAGGTGCGCAGCGAATGGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References