Detailed information of TA system TA119891

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): tad-ata/COG5606-COG4679
• Location: 2607057..2607766
• Replicon: chromosome
• Accession: NZ_CP036498
• Organism: Rhodopseudomonas sp. SK50-23

Toxin (Protein)

• Gene name: tad
• Uniprot ID: -
• Locus tag: RPMA_RS12175
• Protein ID: WP_211913037.1
• Coordinates: 2607395..2607766 (-)
• Length: 124 a.a.

Antitoxin (Protein)

• Gene name: ata
• Uniprot ID: -
• Locus tag: RPMA_RS12170
• Protein ID: WP_211913036.1
• Coordinates: 2607057..2607398 (-)
• Length: 114 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
RPMA_RS12145 (RPMA_12085)	2602490..2603260	-	771	WP_249225646.1	polysaccharide deacetylase family protein	-
RPMA_RS12150 (RPMA_12090)	2603427..2604857	+	1431	WP_211913033.1	magnesium transporter	-
RPMA_RS12155 (RPMA_12095)	2604918..2605232	+	315	WP_211913034.1	helix-turn-helix domain-containing protein	-
RPMA_RS12160 (RPMA_12100)	2605276..2606094	+	819	WP_211913626.1	aldo/keto reductase	-
RPMA_RS12165 (RPMA_12105)	2606256..2607056	+	801	WP_211913035.1	YdcF family protein	-
RPMA_RS12170 (RPMA_12110)	2607057..2607398	-	342	WP_211913036.1	helix-turn-helix transcriptional regulator	Antitoxin
RPMA_RS12175 (RPMA_12115)	2607395..2607766	-	372	WP_211913037.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
RPMA_RS12180 (RPMA_12120)	2607829..2608167	-	339	WP_211913038.1	DUF3253 domain-containing protein	-
RPMA_RS12185 (RPMA_12125)	2608282..2609217	+	936	WP_211913039.1	hypothetical protein	-
RPMA_RS12190 (RPMA_12130)	2609252..2609980	-	729	WP_211913040.1	DUF599 family protein	-
RPMA_RS12195 (RPMA_12135)	2610124..2610780	+	657	WP_211913041.1	glutathione S-transferase family protein	-
RPMA_RS12200 (RPMA_12140)	2610894..2611862	+	969	WP_211913042.1	hypothetical protein	-
RPMA_RS12205 (RPMA_12145)	2611867..2612304	+	438	WP_211913043.1	DUF1489 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin HigB-like (19-109)

Antitoxin

• HigA2-like, helix-turn-helix domain (17-96)

Sequences

Toxin

Protein

• Length: 124 a.a.
• Molecular weight: 14025.14 Da
• Isoelectric Point: 10.6505

>T119891 WP_211913037.1 NZ_CP036498:c2607766-2607395 [Rhodopseudomonas sp. SK50-23]
VSDPLRRVKPLVFVGSSQKDLRAFPAAVRRDVGVALFDAQLGIHPHNAKPLKGMNGVLEIRDNYDGYTYRAVYTIRFEGI
LYVLHAFQKKSTSGIATPQRHIDMIRQRLRIAEDIHKDNRDRG

Nucleotide

• Length: 372 bp

>T119891 NZ_CP036498:c2607766-2607395 [Rhodopseudomonas sp. SK50-23]
GTGAGCGATCCGCTGCGTCGGGTCAAACCTCTCGTCTTCGTGGGCTCGAGCCAGAAGGATCTGCGGGCCTTCCCCGCGGC
TGTCCGCAGAGACGTCGGCGTCGCGCTGTTCGACGCGCAGCTCGGCATTCACCCTCACAATGCCAAACCACTCAAAGGCA
TGAATGGGGTTTTGGAAATTCGTGACAACTACGATGGCTACACCTATCGCGCGGTCTACACGATACGTTTCGAAGGCATC
TTGTACGTCCTGCACGCGTTTCAGAAAAAATCGACAAGCGGCATCGCCACGCCGCAACGACATATCGACATGATCAGGCA
ACGCCTGCGCATCGCCGAGGATATTCACAAGGACAACAGGGATCGCGGATGA

Antitoxin

Protein

• Length: 114 a.a.
• Molecular weight: 12410.60 Da
• Isoelectric Point: 11.0815

>AT119891 WP_211913036.1 NZ_CP036498:c2607398-2607057 [Rhodopseudomonas sp. SK50-23]
MTNKKASPAFTRGSGNVFADLGLPDAEELHLKAALVVELKRLIAARDMTQTAAAKLIAMSQPDLSKLLRGQLQLASVERL
MRMLTTFEQDIEITIRPRRKRGEAGRITLVPAA

Nucleotide

• Length: 342 bp

>AT119891 NZ_CP036498:c2607398-2607057 [Rhodopseudomonas sp. SK50-23]
ATGACGAACAAGAAAGCTTCACCCGCTTTTACAAGAGGCTCCGGCAACGTGTTCGCCGACCTGGGCCTGCCCGATGCCGA
AGAACTGCATCTAAAGGCAGCACTCGTTGTCGAATTGAAACGGCTGATCGCCGCGCGTGACATGACGCAGACGGCGGCCG
CGAAACTGATTGCCATGTCGCAGCCCGACCTCTCGAAGCTGCTACGCGGTCAATTGCAACTGGCGTCCGTCGAGCGGCTG
ATGCGCATGCTGACGACGTTCGAGCAAGACATCGAGATCACGATCCGCCCTCGCCGCAAACGTGGCGAAGCTGGACGGAT
CACACTCGTTCCGGCGGCGTGA