Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 2505055..2505652 Replicon chromosome
Accession NZ_CP036498
Organism Rhodopseudomonas sp. SK50-23

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag RPMA_RS11680 Protein ID WP_211912957.1
Coordinates 2505055..2505351 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag RPMA_RS11685 Protein ID WP_211912958.1
Coordinates 2505356..2505652 (+) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RPMA_RS11660 (RPMA_11605) 2500790..2501944 - 1155 WP_211912953.1 efflux RND transporter periplasmic adaptor subunit -
RPMA_RS11665 (RPMA_11610) 2502693..2503628 + 936 WP_211912954.1 tonB-system energizer ExbB -
RPMA_RS11670 (RPMA_11615) 2503631..2504104 + 474 WP_211912955.1 TonB system transport protein ExbD -
RPMA_RS11675 (RPMA_11620) 2504119..2504904 + 786 WP_211912956.1 TonB family protein -
RPMA_RS11680 (RPMA_11625) 2505055..2505351 + 297 WP_211912957.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
RPMA_RS11685 (RPMA_11630) 2505356..2505652 + 297 WP_211912958.1 putative addiction module antidote protein Antitoxin
RPMA_RS11690 (RPMA_11635) 2505704..2506450 - 747 WP_211912959.1 SDR family NAD(P)-dependent oxidoreductase -
RPMA_RS11695 (RPMA_11640) 2506614..2507348 - 735 WP_211912960.1 SDR family oxidoreductase -
RPMA_RS11700 (RPMA_11645) 2507492..2509321 - 1830 WP_211912961.1 IlvD/Edd family dehydratase -
RPMA_RS11705 (RPMA_11650) 2509553..2510619 + 1067 Protein_2308 sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-95)

Antitoxin

Uncharacterized protein HI1420

(5-92)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 10882.54 Da        Isoelectric Point: 10.3379

>T119889 WP_211912957.1 NZ_CP036498:2505055-2505351 [Rhodopseudomonas sp. SK50-23]
VIEVRETPEFTRWLAALKDQRAVLHVVRRIARVAAGNFGDVKSVGGVVSELRIDYGPGYRVYFTRRGAVIVVLLCGGDKR
TQSRDIKRAAEIAGQLED

Download         Length: 297 bp

>T119889 NZ_CP036498:2505055-2505351 [Rhodopseudomonas sp. SK50-23]
GTGATCGAGGTTCGCGAAACACCTGAGTTCACCCGGTGGCTGGCCGCTTTGAAAGATCAGCGCGCCGTCCTTCATGTCGT
TCGCCGGATCGCTCGTGTCGCTGCAGGCAATTTCGGAGACGTGAAGTCAGTGGGTGGTGTCGTGTCCGAGCTGCGGATCG
ACTACGGCCCCGGATATCGCGTCTACTTTACGCGACGCGGCGCGGTGATCGTCGTTCTGCTTTGTGGCGGCGACAAGCGC
ACGCAGAGTCGGGATATCAAACGCGCAGCCGAGATCGCCGGTCAGTTGGAGGATTGA

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 10347.88 Da        Isoelectric Point: 7.2030

>AT119889 WP_211912958.1 NZ_CP036498:2505356-2505652 [Rhodopseudomonas sp. SK50-23]
MKTGKLKKFDAAEHLTTPEARAEYLSIVLADGDPAEVRDALNIVARAQGMSEVARAAGVTREGLYKTLGETGNPEFATIL
KVIGALGIRLSAHAVDAK

Download         Length: 297 bp

>AT119889 NZ_CP036498:2505356-2505652 [Rhodopseudomonas sp. SK50-23]
ATGAAAACCGGCAAGCTGAAAAAGTTCGACGCCGCCGAGCATTTGACGACGCCGGAGGCGCGCGCCGAATATCTGAGCAT
CGTTCTGGCCGATGGCGATCCTGCCGAAGTCCGCGATGCTCTCAACATCGTTGCCCGTGCACAGGGCATGAGTGAGGTCG
CGCGTGCCGCTGGTGTGACCCGAGAAGGGCTTTACAAGACGCTCGGGGAGACTGGCAATCCGGAGTTCGCGACGATCCTG
AAAGTCATCGGCGCGTTAGGAATCCGCCTTTCAGCGCACGCGGTCGACGCAAAGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References