Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 1198529..1199174 Replicon chromosome
Accession NZ_CP036498
Organism Rhodopseudomonas sp. SK50-23

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag RPMA_RS05650 Protein ID WP_249225560.1
Coordinates 1198812..1199174 (+) Length 121 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag RPMA_RS05645 Protein ID WP_211911916.1
Coordinates 1198529..1198759 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RPMA_RS05615 (RPMA_05585) 1193574..1194503 + 930 WP_211911911.1 bile acid:sodium symporter family protein -
RPMA_RS05620 (RPMA_05590) 1194500..1195468 + 969 WP_211911912.1 SDR family oxidoreductase -
RPMA_RS05625 (RPMA_05595) 1195518..1196741 + 1224 WP_249225559.1 NAD(P)-binding domain-containing protein -
RPMA_RS05630 (RPMA_05600) 1196791..1197465 + 675 WP_211911913.1 dienelactone hydrolase family protein -
RPMA_RS05635 (RPMA_05605) 1197478..1197972 + 495 WP_211911914.1 GNAT family N-acetyltransferase -
RPMA_RS05640 (RPMA_05610) 1197969..1198439 + 471 WP_211911915.1 GNAT family N-acetyltransferase -
RPMA_RS05645 (RPMA_05615) 1198529..1198759 + 231 WP_211911916.1 AbrB family transcriptional regulator Antitoxin
RPMA_RS05650 (RPMA_05620) 1198812..1199174 + 363 WP_249225560.1 PIN domain-containing protein Toxin
RPMA_RS05655 (RPMA_05625) 1199375..1201537 + 2163 WP_211911918.1 anthranilate synthase component I -
RPMA_RS05660 (RPMA_05630) 1201641..1202186 + 546 WP_211911919.1 adenine phosphoribosyltransferase -
RPMA_RS05665 (RPMA_05635) 1202192..1202854 - 663 WP_211911920.1 hypothetical protein -
RPMA_RS05670 (RPMA_05640) 1203067..1203822 - 756 WP_211911921.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(14-93)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 121 a.a.        Molecular weight: 13349.11 Da        Isoelectric Point: 4.4153

>T119887 WP_249225560.1 NZ_CP036498:1198812-1199174 [Rhodopseudomonas sp. SK50-23]
VERVQNLVDDGGNVSVQVLNEMANVSRRKFGMSWQQTSQFINRTVRLFDIWPVTVDIHKDGLRLAERYGFAIYDSFIVAA
ALAADCDTLWSEDMQAGMVVDGRLTIANPFQGDPSLIPAS

Download         Length: 363 bp

>T119887 NZ_CP036498:1198812-1199174 [Rhodopseudomonas sp. SK50-23]
GTGGAGAGAGTCCAAAATCTTGTCGATGATGGCGGTAATGTCAGCGTCCAAGTGCTGAACGAAATGGCCAATGTGTCGCG
ACGCAAGTTTGGCATGTCGTGGCAGCAGACGTCGCAGTTCATCAACCGAACAGTGAGGCTTTTCGATATATGGCCGGTCA
CCGTTGACATTCACAAAGACGGCCTCCGCCTCGCCGAACGCTACGGCTTCGCCATCTATGACAGCTTCATCGTCGCTGCG
GCCCTTGCGGCGGATTGCGACACCCTCTGGTCCGAAGACATGCAGGCCGGCATGGTCGTCGATGGCCGGCTGACAATCGC
AAATCCGTTCCAGGGCGATCCATCCTTGATCCCGGCCTCTTGA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8393.64 Da        Isoelectric Point: 4.7571

>AT119887 WP_211911916.1 NZ_CP036498:1198529-1198759 [Rhodopseudomonas sp. SK50-23]
MIVSKLGDGLIVRLPDNVVETLGLKEGDKVTVRPLDVAPAAATTPAARREVLDELRQFQGMMPADFKFNRDEANER

Download         Length: 231 bp

>AT119887 NZ_CP036498:1198529-1198759 [Rhodopseudomonas sp. SK50-23]
ATGATTGTCTCGAAACTGGGTGATGGCCTGATCGTCAGGCTACCCGACAACGTCGTGGAAACGTTGGGTTTGAAAGAGGG
CGACAAGGTCACTGTTAGACCGCTGGATGTCGCGCCTGCGGCTGCCACAACCCCCGCCGCTCGGAGGGAAGTGCTTGATG
AGCTCCGGCAGTTTCAAGGCATGATGCCGGCCGACTTCAAGTTCAACCGCGACGAGGCGAATGAGCGATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References