Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parE_1-relB/RelE(toxin)
Location 2037993..2038468 Replicon chromosome
Accession NZ_CP036495
Organism Pseudomonas viridiflava strain Psy35

Toxin (Protein)


Gene name parE_1 Uniprot ID -
Locus tag EZZ81_RS09595 Protein ID WP_080665244.1
Coordinates 2038187..2038468 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A5E7EZR3
Locus tag EZZ81_RS09590 Protein ID WP_029242986.1
Coordinates 2037993..2038187 (+) Length 65 a.a.

Genomic Context

EZZ81_RS09570EZZ81_RS09580EZZ81_RS09585EZZ81_RS09590EZZ81_RS09595EZZ81_RS09605EZZ81_RS09610EZZ81_RS09575EZZ81_RS09600EZZ81_RS09615EZZ81_RS09620
Location: 2033015..2033494 (480 bp)
Type: Others
Protein ID: WP_029242983.1
Location: 2036007..2037248 (1242 bp)
Type: Others
Protein ID: WP_029242985.1
Location: 2037346..2037756 (411 bp)
Type: Others
Protein ID: WP_025995307.1
Location: 2037993..2038187 (195 bp)
Type: Antitoxin
Protein ID: WP_029242986.1
Location: 2038187..2038468 (282 bp)
Type: Toxin
Protein ID: WP_080665244.1
Location: 2038877..2039887 (1011 bp)
Type: Others
Protein ID: WP_029242987.1
Location: 2040033..2040464 (432 bp)
Type: Others
Protein ID: WP_029242988.1
Location: 2033569..2035740 (2172 bp)
Type: Others
Protein ID: WP_029242984.1
Location: 2038643..2038771 (129 bp)
Type: Others
Protein ID: Protein_1886
Location: 2040473..2040937 (465 bp)
Type: Others
Protein ID: WP_004881182.1
Location: 2040934..2043261 (2328 bp)
Type: Others
Protein ID: WP_029242989.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
EZZ81_RS09570 (EZZ81_09720)2033015..2033494+480WP_029242983.1ATP-binding protein-
EZZ81_RS09575 (EZZ81_09725)2033569..2035740-2172WP_029242984.1TonB-dependent siderophore receptor-
EZZ81_RS09580 (EZZ81_09730)2036007..2037248+1242WP_029242985.1M20/M25/M40 family metallo-hydrolase-
EZZ81_RS09585 (EZZ81_09735)2037346..2037756+411WP_025995307.1S24 family peptidase-
EZZ81_RS09590 (EZZ81_09740)2037993..2038187+195WP_029242986.1hypothetical proteinAntitoxin
EZZ81_RS09595 (EZZ81_09745)2038187..2038468+282WP_080665244.1type II toxin-antitoxin system RelE/ParE family toxinToxin
EZZ81_RS096002038643..2038771-129Protein_1886site-specific integrase-
EZZ81_RS09605 (EZZ81_09750)2038877..2039887+1011WP_029242987.1tRNA dihydrouridine(20/20a) synthase DusA-
EZZ81_RS09610 (EZZ81_09755)2040033..2040464+432WP_029242988.1universal stress protein-
EZZ81_RS09615 (EZZ81_09760)2040473..2040937-465WP_004881182.1response regulator-
EZZ81_RS09620 (EZZ81_09765)2040934..2043261-2328WP_029242989.1ATP-binding protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10517.27 Da        Isoelectric Point: 9.8796

>T119883 WP_080665244.1 NZ_CP036495:2038187-2038468 [Pseudomonas viridiflava]
MLPIVWLQAAVNDLSSIILYISNENPSAARRLKSRLQAAPLPLVEHPYLFPLGRVSGTRELVAHPNYIIVYRIASDRVEI
VNVLHSRQTYPLT

Download         Length: 282 bp

>T119883 NZ_CP036495:2038187-2038468 [Pseudomonas viridiflava]
ATGTTGCCCATTGTCTGGCTGCAAGCTGCTGTAAATGACCTTTCTTCAATCATCCTCTACATCTCCAATGAAAACCCCTC
TGCCGCTCGTCGCCTAAAATCACGTCTTCAGGCTGCGCCTTTACCATTAGTTGAACATCCTTATCTTTTTCCTCTGGGGC
GGGTTTCCGGTACGCGCGAACTCGTCGCGCATCCCAATTACATCATCGTTTACCGCATTGCCTCAGATCGAGTGGAGATC
GTGAACGTCTTGCATTCAAGGCAGACCTATCCGTTGACATGA

Antitoxin


Download         Length: 65 a.a.        Molecular weight: 7095.90 Da        Isoelectric Point: 4.1947

>AT119883 WP_029242986.1 NZ_CP036495:2037993-2038187 [Pseudomonas viridiflava]
MSTTLSPIVSEFDTQEQADSYDLWFRAKVEASLAEPGRAVPHDEVMARMDAIIEAAEARQRLGS

Download         Length: 195 bp

>AT119883 NZ_CP036495:2037993-2038187 [Pseudomonas viridiflava]
ATGAGCACTACACTTTCCCCCATCGTTTCCGAATTTGATACGCAAGAGCAAGCTGATAGCTACGATCTCTGGTTTCGCGC
CAAGGTGGAAGCTTCGTTGGCCGAACCTGGACGTGCAGTGCCTCACGATGAAGTCATGGCGCGCATGGACGCGATCATTG
AGGCTGCTGAGGCCAGGCAGAGATTGGGTAGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A5E7EZR3

References