Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | /RES-TIGR02293 |
| Location | 3415586..3416469 | Replicon | chromosome |
| Accession | NZ_CP036494 | ||
| Organism | Pseudomonas putida strain PP1 | ||
Toxin (Protein)
| Gene name | - | Uniprot ID | Q88K57 |
| Locus tag | EZZ80_RS15780 | Protein ID | WP_003250527.1 |
| Coordinates | 3415586..3416023 (-) | Length | 146 a.a. |
Antitoxin (Protein)
| Gene name | - | Uniprot ID | I7C3Q7 |
| Locus tag | EZZ80_RS15785 | Protein ID | WP_003250525.1 |
| Coordinates | 3416020..3416469 (-) | Length | 150 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EZZ80_RS15755 (EZZ80_16050) | 3411130..3411519 | - | 390 | WP_049587628.1 | hypothetical protein | - |
| EZZ80_RS15760 (EZZ80_16055) | 3411522..3411770 | - | 249 | Protein_3126 | PAAR domain-containing protein | - |
| EZZ80_RS15765 (EZZ80_16060) | 3411934..3413163 | - | 1230 | WP_049587623.1 | acyl-CoA dehydrogenase | - |
| EZZ80_RS15770 (EZZ80_16065) | 3413304..3414230 | + | 927 | WP_010953387.1 | LysR family transcriptional regulator | - |
| EZZ80_RS15775 (EZZ80_16070) | 3414424..3415578 | + | 1155 | WP_049587669.1 | aminotransferase class V-fold PLP-dependent enzyme | - |
| EZZ80_RS15780 (EZZ80_16075) | 3415586..3416023 | - | 438 | WP_003250527.1 | RES family NAD+ phosphorylase | Toxin |
| EZZ80_RS15785 (EZZ80_16080) | 3416020..3416469 | - | 450 | WP_003250525.1 | DUF2384 domain-containing protein | Antitoxin |
| EZZ80_RS15790 (EZZ80_16085) | 3416612..3417265 | - | 654 | WP_010953384.1 | oxygen-insensitive NAD(P)H-dependent nitroreductase NfsB | - |
| EZZ80_RS15795 (EZZ80_16090) | 3417369..3418292 | + | 924 | WP_010953383.1 | LysR family transcriptional regulator | - |
| EZZ80_RS15800 (EZZ80_16095) | 3418341..3419171 | + | 831 | WP_003250518.1 | AraC family transcriptional regulator | - |
| EZZ80_RS15805 (EZZ80_16100) | 3419222..3419806 | + | 585 | WP_010953382.1 | LysE family transporter | - |
| EZZ80_RS15810 (EZZ80_16105) | 3419846..3421045 | - | 1200 | WP_049587621.1 | sugar transporter | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 146 a.a. Molecular weight: 15990.29 Da Isoelectric Point: 5.6007
>T119876 WP_003250527.1 NZ_CP036494:c3416023-3415586 [Pseudomonas putida]
VILWRISAYADLSGTGGLRVSGRWHQAGRPVVYAATSPPGAMLEVLVHLEIDPEDFPTTMRLLRIELPDTVSQAQLPALQ
PGWSAQPELTRTLGNRFLDDCSALLLPVPSAIMPSTTNYLFNPRHPQAQSAKIQVEDFTPDSRLF
VILWRISAYADLSGTGGLRVSGRWHQAGRPVVYAATSPPGAMLEVLVHLEIDPEDFPTTMRLLRIELPDTVSQAQLPALQ
PGWSAQPELTRTLGNRFLDDCSALLLPVPSAIMPSTTNYLFNPRHPQAQSAKIQVEDFTPDSRLF
Download Length: 438 bp
>T119876 NZ_CP036494:c3416023-3415586 [Pseudomonas putida]
GTGATTTTGTGGCGAATCAGCGCCTATGCAGACTTGAGCGGTACGGGGGGCTTGCGTGTAAGTGGCCGCTGGCACCAGGC
GGGTCGGCCGGTGGTGTATGCCGCCACCAGCCCTCCTGGGGCGATGCTGGAAGTGTTGGTGCACCTGGAGATCGACCCCG
AGGATTTCCCTACCACCATGCGCTTGCTTCGCATCGAACTGCCCGACACGGTTTCCCAGGCGCAGTTGCCCGCTTTGCAG
CCCGGCTGGTCTGCTCAGCCTGAGTTGACCCGAACGCTGGGCAATCGCTTTCTGGATGACTGTTCGGCATTGCTGCTGCC
GGTGCCAAGCGCGATCATGCCCAGCACCACCAATTACCTGTTCAACCCACGGCACCCGCAGGCGCAGAGCGCGAAAATCC
AGGTTGAGGATTTCACGCCGGACAGCCGCCTGTTCTAG
GTGATTTTGTGGCGAATCAGCGCCTATGCAGACTTGAGCGGTACGGGGGGCTTGCGTGTAAGTGGCCGCTGGCACCAGGC
GGGTCGGCCGGTGGTGTATGCCGCCACCAGCCCTCCTGGGGCGATGCTGGAAGTGTTGGTGCACCTGGAGATCGACCCCG
AGGATTTCCCTACCACCATGCGCTTGCTTCGCATCGAACTGCCCGACACGGTTTCCCAGGCGCAGTTGCCCGCTTTGCAG
CCCGGCTGGTCTGCTCAGCCTGAGTTGACCCGAACGCTGGGCAATCGCTTTCTGGATGACTGTTCGGCATTGCTGCTGCC
GGTGCCAAGCGCGATCATGCCCAGCACCACCAATTACCTGTTCAACCCACGGCACCCGCAGGCGCAGAGCGCGAAAATCC
AGGTTGAGGATTTCACGCCGGACAGCCGCCTGTTCTAG
Antitoxin
Download Length: 150 a.a. Molecular weight: 16956.46 Da Isoelectric Point: 5.7258
>AT119876 WP_003250525.1 NZ_CP036494:c3416469-3416020 [Pseudomonas putida]
MLAEVLRDNGYHEYRARLQALLDIPELASDFEIHTRITDGFAATWLVKLTERGVLTPVERDQIIPLRTLKSRIERDQPLT
VDESDRLFRSAHITAMAEAVFGEAGKAKRWLSKPKERFSGLTPMQMLTTQQGTTQVEEMLLQIAEGYGL
MLAEVLRDNGYHEYRARLQALLDIPELASDFEIHTRITDGFAATWLVKLTERGVLTPVERDQIIPLRTLKSRIERDQPLT
VDESDRLFRSAHITAMAEAVFGEAGKAKRWLSKPKERFSGLTPMQMLTTQQGTTQVEEMLLQIAEGYGL
Download Length: 450 bp
>AT119876 NZ_CP036494:c3416469-3416020 [Pseudomonas putida]
ATGCTTGCCGAAGTGCTTCGCGACAACGGTTACCACGAGTACCGGGCGCGCCTGCAGGCGCTGCTGGACATTCCCGAGCT
TGCCAGCGATTTCGAAATCCACACCCGCATCACCGATGGTTTTGCCGCCACCTGGTTGGTAAAGCTGACCGAACGCGGTG
TGCTCACGCCGGTGGAGCGCGACCAGATCATCCCGCTGCGCACCCTCAAATCCCGTATCGAGCGTGACCAACCGCTGACC
GTGGATGAGAGCGATCGGCTGTTCCGCTCGGCCCACATCACCGCCATGGCCGAGGCCGTGTTCGGTGAAGCGGGCAAGGC
CAAACGCTGGCTTTCCAAGCCCAAGGAACGCTTCTCGGGGCTGACGCCGATGCAGATGCTCACCACCCAGCAAGGCACCA
CGCAGGTCGAAGAAATGCTGCTGCAGATTGCCGAGGGCTATGGCCTGTGA
ATGCTTGCCGAAGTGCTTCGCGACAACGGTTACCACGAGTACCGGGCGCGCCTGCAGGCGCTGCTGGACATTCCCGAGCT
TGCCAGCGATTTCGAAATCCACACCCGCATCACCGATGGTTTTGCCGCCACCTGGTTGGTAAAGCTGACCGAACGCGGTG
TGCTCACGCCGGTGGAGCGCGACCAGATCATCCCGCTGCGCACCCTCAAATCCCGTATCGAGCGTGACCAACCGCTGACC
GTGGATGAGAGCGATCGGCTGTTCCGCTCGGCCCACATCACCGCCATGGCCGAGGCCGTGTTCGGTGAAGCGGGCAAGGC
CAAACGCTGGCTTTCCAAGCCCAAGGAACGCTTCTCGGGGCTGACGCCGATGCAGATGCTCACCACCCAGCAAGGCACCA
CGCAGGTCGAAGAAATGCTGCTGCAGATTGCCGAGGGCTATGGCCTGTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|