Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 2495..3282 Replicon plasmid pER79ag33
Accession NZ_CP036467
Organism Zymomonas mobilis strain ER79ag

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag EWS78_RS09200 Protein ID WP_062339594.1
Coordinates 2788..3282 (+) Length 165 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag EWS78_RS09195 Protein ID WP_062339592.1
Coordinates 2495..2791 (+) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EWS78_RS09175 410..646 + 237 WP_062339585.1 hypothetical protein -
EWS78_RS09180 643..1224 + 582 WP_062339588.1 zeta toxin family protein -
EWS78_RS09185 1358..1618 - 261 WP_062339589.1 ribbon-helix-helix protein, CopG family -
EWS78_RS09190 1648..2298 - 651 WP_062339590.1 AAA family ATPase -
EWS78_RS09195 2495..2791 + 297 WP_062339592.1 DUF1778 domain-containing protein Antitoxin
EWS78_RS09200 2788..3282 + 495 WP_062339594.1 GNAT family N-acetyltransferase Toxin
EWS78_RS09205 3635..4540 - 906 WP_062339596.1 LysR family transcriptional regulator -
EWS78_RS09210 4763..6196 + 1434 WP_108125217.1 carbohydrate porin -
EWS78_RS09215 6213..7508 + 1296 WP_062339600.1 C4-dicarboxylate transporter DctA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..33007 33007


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(43-144)

Antitoxin

Vibrio phage ICP1, Orf50

(16-90)


Sequences

Toxin        


Download         Length: 165 a.a.        Molecular weight: 17994.99 Da        Isoelectric Point: 9.9205

>T119856 WP_062339594.1 NZ_CP036467:2788-3282 [Zymomonas mobilis]
VTITAPELVSPEHQVDLFQSGVESLDLWLKKRALKNQMTGASRTFVACKNRRVIAYYALASSAITIKSAHGRFRRNMPDP
IPVVVLGRLAIDQSLHNQGVGRAMVRDAALRIIQAADTIGIRGMLVHALSDEAKSFYEHIGFEPSPIDPMMLMVTLADLK
SSLA

Download         Length: 495 bp

>T119856 NZ_CP036467:2788-3282 [Zymomonas mobilis]
GTGACAATAACAGCTCCAGAATTAGTATCCCCAGAACATCAAGTTGACTTATTTCAGTCCGGTGTAGAGAGCCTTGATCT
ATGGTTAAAAAAGCGCGCTTTGAAAAATCAAATGACAGGAGCCTCTCGTACCTTTGTAGCCTGTAAAAATCGACGGGTGA
TAGCCTATTATGCTCTAGCATCTAGCGCTATCACTATAAAATCAGCCCATGGACGATTTAGGCGTAATATGCCAGATCCT
ATTCCTGTTGTCGTTTTAGGGCGGCTTGCTATTGATCAATCTTTACATAACCAAGGCGTTGGACGAGCAATGGTAAGGGA
TGCAGCCTTAAGGATAATACAGGCAGCTGATACTATCGGAATTAGAGGTATGCTCGTTCATGCGCTATCTGATGAAGCCA
AATCTTTCTACGAACATATCGGTTTCGAACCGTCTCCAATCGACCCAATGATGTTGATGGTTACATTAGCCGATTTAAAG
TCGAGCCTTGCTTAG

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 11258.00 Da        Isoelectric Point: 7.7936

>AT119856 WP_062339592.1 NZ_CP036467:2495-2791 [Zymomonas mobilis]
MTAATTIPSPNKREALNIRIKPEERDLIDRAAKIQRKSRTNFVLEAACRAAEEALFDQCLISVDPKAYTDFLMRLDMPPR
PNDRLQKTMQTVAPWDEL

Download         Length: 297 bp

>AT119856 NZ_CP036467:2495-2791 [Zymomonas mobilis]
ATGACAGCTGCAACAACGATACCTTCTCCAAATAAGCGAGAAGCGCTAAATATCAGAATTAAACCGGAAGAACGGGATTT
AATAGATCGAGCAGCAAAGATTCAGAGAAAAAGTCGTACTAATTTTGTATTGGAAGCTGCCTGTAGAGCCGCAGAAGAAG
CGCTTTTCGATCAATGTCTCATCTCTGTTGATCCAAAGGCGTATACTGATTTTTTAATGCGCCTCGATATGCCGCCACGC
CCTAATGATCGGCTGCAAAAAACCATGCAAACGGTAGCGCCGTGGGATGAGCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References