119766

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) tad-ata/COG5606-COG4679
Location 1011929..1012595 Replicon chromosome
Accession NZ_CP036435
Organism Citrobacter sp. ABFQG

Toxin (Protein)


Gene name tad Uniprot ID A0A0D7LIM5
Locus tag WN16_RS04960 Protein ID WP_044702260.1
Coordinates 1011929..1012288 (+) Length 120 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID A0A0D7LIR0
Locus tag WN16_RS04965 Protein ID WP_003844682.1
Coordinates 1012278..1012595 (+) Length 106 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
WN16_RS04950 1009329..1010960 + 1632 WP_032938230.1 Na/Pi cotransporter family protein -
WN16_RS04955 1011026..1011715 - 690 WP_003841421.1 dipeptidase PepE -
WN16_RS04960 1011929..1012288 + 360 WP_044702260.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
WN16_RS04965 1012278..1012595 + 318 WP_003844682.1 helix-turn-helix domain-containing protein Antitoxin
WN16_RS04970 1012605..1012883 - 279 WP_044702262.1 putative addiction module antidote protein -
WN16_RS04975 1013287..1013448 - 162 WP_003841416.1 phage protein -
WN16_RS04980 1013590..1013946 + 357 WP_032948294.1 hypothetical protein -
WN16_RS04985 1013998..1014810 - 813 WP_044702264.1 shikimate 5-dehydrogenase -
WN16_RS04990 1014812..1016035 - 1224 WP_044702265.1 L-sorbose 1-phosphate reductase -
WN16_RS04995 1016104..1016928 - 825 WP_003031641.1 PTS system mannose/fructose/sorbose family transporter subunit IID -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(14-106)

Antitoxin

(12-90)


Sequences


Toxin        


Download         Length: 120 a.a.        Molecular weight: 13437.49 Da        Isoelectric Point: 10.2555

>T119766 WP_044702260.1 NZ_CP036435:1011929-1012288 [Citrobacter sp. ABFQG]
MTKPLYWVGQARKDLIAMPEHVRDTFGFALWLAQQGKQHSQTKPLKGFGGAGVLEVVEDYHGNAWRAVYTIQLKNAVYVL
HVFQKKSVSGKATPKPEIDLIYQRLKAAQRHAQESGYVT

Download         Length: 360 bp

>T119766 NZ_CP036435:1011929-1012288 [Citrobacter sp. ABFQG]
ATGACGAAACCACTTTACTGGGTTGGGCAGGCCAGAAAAGACCTGATTGCAATGCCAGAACACGTTCGGGATACGTTTGG
GTTTGCTCTTTGGCTTGCGCAACAGGGTAAACAGCATTCACAGACTAAACCATTAAAAGGATTTGGTGGAGCGGGGGTTC
TGGAAGTCGTTGAGGATTATCACGGCAACGCCTGGCGGGCGGTTTACACCATCCAGTTGAAAAATGCGGTTTATGTTCTC
CATGTTTTTCAGAAGAAGTCCGTTTCCGGGAAAGCAACCCCGAAACCTGAAATTGACCTGATTTATCAGCGGCTCAAGGC
TGCACAGCGCCATGCGCAGGAGAGTGGATATGTCACATGA

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11466.35 Da        Isoelectric Point: 9.0005

>AT119766 WP_003844682.1 NZ_CP036435:1012278-1012595 [Citrobacter sp. ABFQG]
MSHDVETSSGNVYADLGAYDAEQMQLKAQLAMVIGEILQRKGLTQQQAAQLLGMTQPKLSNLLRGQFRGISEAKMLECLV
RLGRDVEIVVGKEGNMSGKLKVKFG

Download         Length: 318 bp

>AT119766 NZ_CP036435:1012278-1012595 [Citrobacter sp. ABFQG]
ATGTCACATGATGTCGAAACCAGTAGCGGTAATGTTTACGCCGATTTAGGTGCGTATGACGCAGAACAGATGCAGTTGAA
AGCGCAGCTGGCAATGGTGATTGGTGAGATTTTGCAACGCAAAGGGTTAACGCAGCAGCAGGCCGCGCAGTTACTGGGAA
TGACACAGCCTAAACTTTCCAATCTGCTACGCGGCCAGTTTCGCGGTATCAGTGAAGCAAAGATGCTCGAATGCCTGGTG
AGGCTGGGCCGTGATGTAGAGATTGTTGTCGGGAAAGAGGGCAATATGTCAGGAAAGCTGAAAGTGAAATTTGGCTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A0D7LIM5


Antitoxin

Source ID Structure
AlphaFold DB A0A0D7LIR0

References