Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-PHD
Location 3642317..3642951 Replicon chromosome
Accession NZ_CP036402
Organism Egibacter rhizosphaerae strain EGI 80759

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag ER308_RS16715 Protein ID WP_205745683.1
Coordinates 3642562..3642951 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag ER308_RS16710 Protein ID WP_131156045.1
Coordinates 3642317..3642565 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ER308_RS16675 3637475..3637711 + 237 WP_131156038.1 hypothetical protein -
ER308_RS21785 3638220..3638543 + 324 WP_165492187.1 HNH endonuclease -
ER308_RS16685 3638816..3639166 + 351 WP_131156040.1 hypothetical protein -
ER308_RS16690 3639410..3639733 + 324 WP_131156041.1 helix-turn-helix domain-containing protein -
ER308_RS16695 3639789..3640196 + 408 WP_131156042.1 VOC family protein -
ER308_RS16700 3640271..3641194 - 924 WP_205745682.1 cyclase family protein -
ER308_RS16705 3641360..3642169 + 810 WP_131156044.1 MOSC domain-containing protein -
ER308_RS16710 3642317..3642565 + 249 WP_131156045.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
ER308_RS16715 3642562..3642951 + 390 WP_205745683.1 PIN domain-containing protein Toxin
ER308_RS16720 3643090..3643761 - 672 WP_131156047.1 alpha/beta hydrolase -
ER308_RS16725 3643896..3646640 - 2745 WP_131156048.1 EAL domain-containing protein -
ER308_RS16730 3646775..3647338 - 564 WP_131156049.1 hypothetical protein -
ER308_RS16735 3647335..3647595 - 261 WP_131156050.1 helix-turn-helix domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(21-118)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(4-50)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 14173.14 Da        Isoelectric Point: 5.2132

>T119744 WP_205745683.1 NZ_CP036402:3642562-3642951 [Egibacter rhizosphaerae]
VTRGLAHTSLFVAREHGRSLEVERLPEELAVSVITIGELRAGVLAAHDVATRDRRLATLAQASRLDPLTVDRAVADVWAR
LRVELRDAGQRMPVNDAWIAATALAWEVPVVTRDDDFDVTVTGLDTIRV

Download         Length: 390 bp

>T119744 NZ_CP036402:3642562-3642951 [Egibacter rhizosphaerae]
GTGACCCGCGGGCTCGCACACACCAGCCTGTTCGTCGCCCGCGAGCATGGCCGGTCGCTGGAGGTCGAGCGGCTTCCCGA
GGAGTTGGCCGTATCGGTGATCACGATCGGTGAGTTGCGTGCTGGGGTACTGGCGGCGCACGACGTGGCAACCCGCGACC
GGCGGCTGGCCACGCTGGCACAGGCATCACGGCTCGACCCGCTGACTGTTGATCGGGCGGTGGCCGACGTGTGGGCGAGG
CTGCGGGTGGAGCTGCGCGACGCGGGCCAGCGGATGCCGGTCAATGACGCGTGGATCGCCGCGACGGCCCTCGCCTGGGA
GGTTCCGGTGGTCACCCGGGACGACGACTTCGACGTGACGGTTACCGGGCTCGACACGATCCGCGTGTGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9269.38 Da        Isoelectric Point: 4.3030

>AT119744 WP_131156045.1 NZ_CP036402:3642317-3642565 [Egibacter rhizosphaerae]
MVDVASRELRNQTRELLARVEAGEEVRITVAGRPVAELRPLGDRPRWVSRSEFVAWLGRQADPALAEDLTDLAPDTTDEL
EW

Download         Length: 249 bp

>AT119744 NZ_CP036402:3642317-3642565 [Egibacter rhizosphaerae]
ATGGTGGATGTTGCCTCGCGCGAGCTGCGCAATCAGACGCGTGAGCTCCTCGCCCGAGTCGAGGCGGGCGAGGAGGTGCG
GATCACCGTGGCCGGCCGGCCGGTCGCCGAGCTGCGACCTCTCGGCGACCGGCCGCGGTGGGTGTCCCGCTCGGAGTTCG
TAGCGTGGCTCGGGCGTCAGGCTGACCCTGCGCTGGCCGAGGATCTGACCGACCTGGCGCCGGACACGACCGACGAGTTG
GAGTGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References