Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | vapBC/LOTUS_5_Limkain_b1-PHD |
Location | 3642317..3642951 | Replicon | chromosome |
Accession | NZ_CP036402 | ||
Organism | Egibacter rhizosphaerae strain EGI 80759 |
Toxin (Protein)
Gene name | vapC | Uniprot ID | - |
Locus tag | ER308_RS16715 | Protein ID | WP_205745683.1 |
Coordinates | 3642562..3642951 (+) | Length | 130 a.a. |
Antitoxin (Protein)
Gene name | vapB | Uniprot ID | - |
Locus tag | ER308_RS16710 | Protein ID | WP_131156045.1 |
Coordinates | 3642317..3642565 (+) | Length | 83 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
ER308_RS16675 | 3637475..3637711 | + | 237 | WP_131156038.1 | hypothetical protein | - |
ER308_RS21785 | 3638220..3638543 | + | 324 | WP_165492187.1 | HNH endonuclease | - |
ER308_RS16685 | 3638816..3639166 | + | 351 | WP_131156040.1 | hypothetical protein | - |
ER308_RS16690 | 3639410..3639733 | + | 324 | WP_131156041.1 | helix-turn-helix domain-containing protein | - |
ER308_RS16695 | 3639789..3640196 | + | 408 | WP_131156042.1 | VOC family protein | - |
ER308_RS16700 | 3640271..3641194 | - | 924 | WP_205745682.1 | cyclase family protein | - |
ER308_RS16705 | 3641360..3642169 | + | 810 | WP_131156044.1 | MOSC domain-containing protein | - |
ER308_RS16710 | 3642317..3642565 | + | 249 | WP_131156045.1 | type II toxin-antitoxin system prevent-host-death family antitoxin | Antitoxin |
ER308_RS16715 | 3642562..3642951 | + | 390 | WP_205745683.1 | PIN domain-containing protein | Toxin |
ER308_RS16720 | 3643090..3643761 | - | 672 | WP_131156047.1 | alpha/beta hydrolase | - |
ER308_RS16725 | 3643896..3646640 | - | 2745 | WP_131156048.1 | EAL domain-containing protein | - |
ER308_RS16730 | 3646775..3647338 | - | 564 | WP_131156049.1 | hypothetical protein | - |
ER308_RS16735 | 3647335..3647595 | - | 261 | WP_131156050.1 | helix-turn-helix domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 130 a.a. Molecular weight: 14173.14 Da Isoelectric Point: 5.2132
>T119744 WP_205745683.1 NZ_CP036402:3642562-3642951 [Egibacter rhizosphaerae]
VTRGLAHTSLFVAREHGRSLEVERLPEELAVSVITIGELRAGVLAAHDVATRDRRLATLAQASRLDPLTVDRAVADVWAR
LRVELRDAGQRMPVNDAWIAATALAWEVPVVTRDDDFDVTVTGLDTIRV
VTRGLAHTSLFVAREHGRSLEVERLPEELAVSVITIGELRAGVLAAHDVATRDRRLATLAQASRLDPLTVDRAVADVWAR
LRVELRDAGQRMPVNDAWIAATALAWEVPVVTRDDDFDVTVTGLDTIRV
Download Length: 390 bp
>T119744 NZ_CP036402:3642562-3642951 [Egibacter rhizosphaerae]
GTGACCCGCGGGCTCGCACACACCAGCCTGTTCGTCGCCCGCGAGCATGGCCGGTCGCTGGAGGTCGAGCGGCTTCCCGA
GGAGTTGGCCGTATCGGTGATCACGATCGGTGAGTTGCGTGCTGGGGTACTGGCGGCGCACGACGTGGCAACCCGCGACC
GGCGGCTGGCCACGCTGGCACAGGCATCACGGCTCGACCCGCTGACTGTTGATCGGGCGGTGGCCGACGTGTGGGCGAGG
CTGCGGGTGGAGCTGCGCGACGCGGGCCAGCGGATGCCGGTCAATGACGCGTGGATCGCCGCGACGGCCCTCGCCTGGGA
GGTTCCGGTGGTCACCCGGGACGACGACTTCGACGTGACGGTTACCGGGCTCGACACGATCCGCGTGTGA
GTGACCCGCGGGCTCGCACACACCAGCCTGTTCGTCGCCCGCGAGCATGGCCGGTCGCTGGAGGTCGAGCGGCTTCCCGA
GGAGTTGGCCGTATCGGTGATCACGATCGGTGAGTTGCGTGCTGGGGTACTGGCGGCGCACGACGTGGCAACCCGCGACC
GGCGGCTGGCCACGCTGGCACAGGCATCACGGCTCGACCCGCTGACTGTTGATCGGGCGGTGGCCGACGTGTGGGCGAGG
CTGCGGGTGGAGCTGCGCGACGCGGGCCAGCGGATGCCGGTCAATGACGCGTGGATCGCCGCGACGGCCCTCGCCTGGGA
GGTTCCGGTGGTCACCCGGGACGACGACTTCGACGTGACGGTTACCGGGCTCGACACGATCCGCGTGTGA
Antitoxin
Download Length: 83 a.a. Molecular weight: 9269.38 Da Isoelectric Point: 4.3030
>AT119744 WP_131156045.1 NZ_CP036402:3642317-3642565 [Egibacter rhizosphaerae]
MVDVASRELRNQTRELLARVEAGEEVRITVAGRPVAELRPLGDRPRWVSRSEFVAWLGRQADPALAEDLTDLAPDTTDEL
EW
MVDVASRELRNQTRELLARVEAGEEVRITVAGRPVAELRPLGDRPRWVSRSEFVAWLGRQADPALAEDLTDLAPDTTDEL
EW
Download Length: 249 bp
>AT119744 NZ_CP036402:3642317-3642565 [Egibacter rhizosphaerae]
ATGGTGGATGTTGCCTCGCGCGAGCTGCGCAATCAGACGCGTGAGCTCCTCGCCCGAGTCGAGGCGGGCGAGGAGGTGCG
GATCACCGTGGCCGGCCGGCCGGTCGCCGAGCTGCGACCTCTCGGCGACCGGCCGCGGTGGGTGTCCCGCTCGGAGTTCG
TAGCGTGGCTCGGGCGTCAGGCTGACCCTGCGCTGGCCGAGGATCTGACCGACCTGGCGCCGGACACGACCGACGAGTTG
GAGTGGTGA
ATGGTGGATGTTGCCTCGCGCGAGCTGCGCAATCAGACGCGTGAGCTCCTCGCCCGAGTCGAGGCGGGCGAGGAGGTGCG
GATCACCGTGGCCGGCCGGCCGGTCGCCGAGCTGCGACCTCTCGGCGACCGGCCGCGGTGGGTGTCCCGCTCGGAGTTCG
TAGCGTGGCTCGGGCGTCAGGCTGACCCTGCGCTGGCCGAGGATCTGACCGACCTGGCGCCGGACACGACCGACGAGTTG
GAGTGGTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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