Detailed information of TA system TA119743

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-VapB
• Location: 3403212..3403873
• Replicon: chromosome
• Accession: NZ_CP036402
• Organism: Egibacter rhizosphaerae strain EGI 80759

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: ER308_RS15685
• Protein ID: WP_131155864.1
• Coordinates: 3403212..3403634 (-)
• Length: 141 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: ER308_RS15690
• Protein ID: WP_131155865.1
• Coordinates: 3403631..3403873 (-)
• Length: 81 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ER308_RS15680	3399058..3403215	-	4158	WP_131155863.1	TIGR02680 family protein	-
ER308_RS15685	3403212..3403634	-	423	WP_131155864.1	PIN domain nuclease	Toxin
ER308_RS15690	3403631..3403873	-	243	WP_131155865.1	type II toxin-antitoxin system VapB family antitoxin	Antitoxin
ER308_RS15695	3403883..3405178	-	1296	WP_205745657.1	TIGR02678 family protein	-
ER308_RS15700	3405175..3406839	-	1665	WP_205745658.1	TIGR02677 family protein	-
ER308_RS15705	3407050..3408174	-	1125	WP_131155866.1	glycosyltransferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (2-123)

Antitoxin

• Bacterial antitoxin of type II TA system, VapB (5-41)

Sequences

Toxin

Protein

• Length: 141 a.a.
• Molecular weight: 15258.44 Da
• Isoelectric Point: 6.0770

>T119743 WP_131155864.1 NZ_CP036402:c3403634-3403212 [Egibacter rhizosphaerae]
VILVDTSAWIEHDRATGSPCDLRMQDLLARDDPSIAVTEPVTAEVLAGARTDARERQLPRLLDRCALLPFETPTDFDGAV
RIYRACRQRGTTFRSLHDCLIAAVALRHGAPVLAHDTDFARMASVVPLALDLATQGTKPA

Nucleotide

• Length: 423 bp

>T119743 NZ_CP036402:c3403634-3403212 [Egibacter rhizosphaerae]
GTGATCCTGGTCGACACCTCGGCCTGGATCGAGCACGACCGGGCCACGGGAAGCCCGTGCGACCTCCGCATGCAGGACCT
CCTCGCCCGCGATGATCCCTCGATCGCGGTGACCGAGCCCGTCACCGCAGAGGTCCTCGCTGGTGCACGTACCGACGCTC
GCGAGCGGCAGCTGCCACGACTCCTCGATCGGTGCGCCCTGCTGCCGTTCGAGACGCCTACCGACTTCGACGGCGCGGTG
CGCATCTACCGAGCATGCCGACAACGAGGCACCACCTTCCGCAGCCTCCACGACTGTCTCATCGCGGCCGTGGCCCTCCG
GCACGGAGCCCCGGTCCTCGCCCACGACACCGACTTCGCGCGGATGGCAAGCGTAGTGCCGCTTGCCCTCGACCTCGCCA
CTCAGGGGACTAAACCCGCATGA

Antitoxin

Protein

• Length: 81 a.a.
• Molecular weight: 9091.28 Da
• Isoelectric Point: 4.3596

>AT119743 WP_131155865.1 NZ_CP036402:c3403873-3403631 [Egibacter rhizosphaerae]
MVRTRTNIELEDDDVARVMERYRLRTKTEAVALALRHLAGQPMTRDEALGMRGAHAIDPIPEDDLDLLDPPIEGERVEPE

Nucleotide

• Length: 243 bp

>AT119743 NZ_CP036402:c3403873-3403631 [Egibacter rhizosphaerae]
ATGGTGAGGACGCGAACGAACATCGAGCTCGAGGACGACGACGTGGCGCGCGTCATGGAGCGCTACCGGCTGCGCACCAA
GACCGAGGCCGTCGCCCTGGCGCTGCGCCACCTCGCCGGGCAGCCCATGACGCGCGACGAGGCGCTCGGGATGCGAGGCG
CACACGCCATCGATCCCATCCCCGAGGACGACCTCGACCTCCTCGATCCGCCCATCGAGGGCGAGCGCGTCGAGCCGGAG
TGA